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Introduction to the diagnostic process
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Primary Preventative Medicine
remove or reduce disease risk factors
Secondary Preventative Medicine
early detection of disease (screenings)
Tertiary Preventative Medicine
Limit impact of established disease (procedures to maintain health or help)
Leading causes of death in the USA
Heart disease and cancer
Top causes from all deaths
(note that all causes attribute to common preventable risk factors)
tobacco smoking, hypertension, overweight obesity, and physical inactivity
Functions of the history and physical exam
information collection
determination of patient values
assessment and communication of prognosis
establishment of a therapeutic relationship
discussion of diagnostic testing and therapeutic options
counseling, education and motivation for behavioral changes
Compliance
the extent to which the patient’s behavior coincides with clinical advice (negative connotation the physician as a dictator)
Adherence
the extent to which a patient’s behavior corresponds with agreed recommendations from a health care provider (patient and physician work together)
Ways to improve adherence
clinical patient goals agreement, education, provide more convenient care, simplify treatment regimens, reminders, monitoring, and support system
What are screening tests used for?
used to identify a disease/condition in a seemingly well person
Criteria used to determine if screening test is worthwhile
burden of disease sufficiency
test used must be high quality
evidence shows screening decreases morbidity and morality
risk of harm
Levels of certainty
net benefit - harm (high, moderate, low)
Grade A recommendations
USPSTF recommends service with high certainty
Grade B recommendations
USPSTF recommends service with moderate certainty (is it worth it for this specific patient)
Grade C recommendations
USPSTF selectively recommends small benefit
Grade D recommendations
USPSTF recommends against service
Grade I recommendations
insufficient evidence
Prevention of infectious diseases
Immunization (pediatric vs adult schedule vs travel recommendations)
strategies to improve vaccination rates
What app is used for vaccination recommendations for traveling
CDC travel planning app
Prevention of obesity: physical activity recommendations and benefits (adults)
Minimum of 150min of moderate intensity aerobic activity+ muscle strengthening activity at least 2 days a week
Benefits: weight management and decreased risk for chronic health conditions and improve quality of life
Components of physical fitness
Cardiorespiratory fitness
musculoskeletal fitness
flexibility
balance
speed
cardiorespiratory fitness
aerobic exercise
how well your heart, lungs, and blood vessels supply oxygen to your muscles during sustained physical activity
Musculoskeletal fitness
ability for muscles, bones, and joints to work together
Prevention of obesity: weight management (diet)
Diet the single most significant risk factor for disability and premature death!!
Diet is shot term like fad diets
Nutrition is a lifestyle with small goals and is sustainable
Dietary patterns:
Dietary approaches to stop hypertension (DASH)
Mediterranean diet
2015 dietary guidelines for Americans (My Plate)
Vegetarian/vegan (have to ensure they are getting proper nutrients)
Prevention of cardiovascular disease
one of the most significant in the United States
coronary heart disease and cerebrovascular accidents are two of the most significant causes of morbidity and mortality in developed countries
There are risk factors that are both modifiable (can be improved) and non modifiable (can not be improved)
Cigarette smoking
SIGNIFICANT cause of preventable morbidity and mortality
increases the risk for almost EVERYTHING
quitting at any Ange can increase life expectancy
Active smoking
the direct act of smoking
Passive smoking
non smoker breaths in smoke from smokers around them
Prevention of cancer
Primary prevention: smoking cessation, uv light restriction/ sunscreen, diet and physical activity, and vaccines
screening and early detection
Prevention of injuries and violence
Injuries remain the most important cause of loss of potential years of life before the age of 65
injury prevention- PATIENT EDUCATION
patient demographics dictate specific topics (examples: seat belts, smoke detectors, CO monitors, poison control knowledge, sunscreen usage, helmet use, texting and driving, gun safety)
Intimate partner violence
Prevalent WORLDWIDE health problem that is largely UNDER RECOGNIZED and UNDERDRESSED
can include physical, emotional, sexual, and financial abuse by current or former partner
IPV tends to be repetitive with an escalation in frequency and severity over time
occurs in heterosexual and same sex relationships
Types of IPV behaviors
physical violence
sexual violence
stalking
phsycclogcial aggression
Possible health outcomes of IPV
The severity of abuse correlates with the impact on physical and mental health (cumulative over time and effects persist long after the abuse has stopped)
Physical effects: related directly to the abuse, develop of chronic medical conditions
Psychological effects: anxiety, depression, substance abuse, eating disorders, PTSD, sleep disorders, low self esteem, and fear of intimacy
Screening of IPV
Patients who present with suspicious symptoms or PE signs
Pregnant women
Initial primary care and OB/GYN visits
All ED visits
All hospital admissions
General principles for IPV screenings
Avoid using the words domestic violence, victim, abused, battered instead use hurt, frightened, treated badly or mirror the patient’s word choice
Never blame the victim
must assess for risk of immediate significant harm
Tools for screening intimate partner violence (IPV)
HITS, STAT, WAST
HARK (Humiliation afraid rape kick), SAFE
OVAT (ongoing violence assessment tool)
Substance Use Disorder
A medical illness caused by repeated misuse of a substance or substances. Characterized by clinically significant impairments in health, social/occupational function, and relationships. May range from mild-severe. Each substance is classified individually
Substance use
the use, even once of any psychoactive compound
Substance misuse
the use of any substance in a manner, situation, amount or frequency that can cause harm to users or to those around them
Addiction
old term used for a sever SUV (no longer used)
Recovery
a process of change through which individuals improve their health and wellness, live a self directed life and strive to reach their full potential
Classification system for substance use disorders
DSM-5
10 specific substances detailed in DSM-5
alcohol
caffeine
cannabis
hallucinogens
inhalants
opioids
sedatives, hypnotics or anxiolytics
stimulants
tobacco
other/unknown substances
intoxication syndromes
intoxication occurs when a person develops a reversible set of symptoms due to the recent use of or exposure to a substance
withdrawal syndromes
the behavioral, physical, and cognitive symptoms that occur due to the abrupt reduction or cessation of substance use
Moderate drinking
up to 1 standard drink a day for woman and 2 drinks a day for men
Low risk drinking
Women: no more than 3 drinks on a single day and no more than 7 drinks a week
Men: no more than 4 drinks on any single day and no more than 14 drinks/week
Binge drinking
consuming an excessive amount of alcohol on a single occasion (or in about 2 hours) Men = +5 drinks, Women= 4+ drinks
Heavy Drinking
binge drinking on 5+ days or more in the past month
Screening for substance use disorder: alcohol use
Need to known amount, frequency, context, age at first use, last use
Past, current use
social use
Screening tools for alcohol use
CAGE/TACE questions
AUDIT alcohol screening tool
Screening for substance use: Illicit (recreational)
Includes street drugs and RX medications taken in ways other than prescribed or not prescribed to patient at all
Need to know specific drugs used, route taken, amount, frequency, context, age at first and last use
Screening tools for illicit substance use
Modified CAGE questions
DAST 10
Contextual environmental factors that a can give rise to health inequity
Poverty
Educational quality
Food insecurity
Access to transportation
Affordable housing
unemployment
maintenance of basic utilities
violence
public safety
Health maintenance and screening: infants and young children
Goals: screening for medical problems and psychosocial concerns
and anticipatory guidance/health promotion
Newborn screening tests
Monitoring of growth and development
Screening considerations for infants and young children
speech and langage
autism (30 month visit to denitrify and step in early to talk to parents)
developmental delay
lead levels
maternal depression
psychosocial concerns
Health maintenance and screening: School age children
Goals of health maintenance visit: health promotion, disease detection, and patient education
special considerations: developmental surveillance, psychosocial review, and school performance/chronic absenteeism
unintentional injury is the leading cause of death for school age children in the USA
Outpatient injury prevention counseling has been shown to decrease injury rates in children (educate children on safety precaution and encourage parents to act as role models)
Health maintenance and screening: adolescents and young adults
Traditionally defined as ages 10-24 years
adolescents are more likely to access health care, have a more favorable attitude about their clinicians, and share sensitive information when confidentiality is assured. However approximately 60% do not get time alone with their clinician for confidential discussions despite patient and parental preferences
Risky health behaviors in adolescents
Most common cause of death: MVA (22%), other unintentional injuries (20%), suicide (17%), and homicide (15%)
approximately 50% of new STIs occur in people ages 15-24
rates of chlamydia, gonorrhea, syphilis all INCREASED between 2015-2016
Must address topics in adolescents/ young adults
Mental health - depression/anxiety
Substance use
Sexual health
teen dating violence
diet/exercise eating disorders
safety
Depression screening adolescents
PHQ2 and PHQ9
self injury: indicative of poor coping mechanisms/diffiluty managing emotions
Preferred screening tool for adolescents substance use
CRAFT+N also looks at adjacent substance use
Adolescents:Sexual health
Opportunity to address sexual orientation and gender identity, safe sexual practices
Teen dating violence screening
TDV is different from adult IPV in many ways
No one screening modality utilize red flags approach and tailor to individual situation
Screening tool for teen dating violence
REDFLAGS approach
Adolescents: diet and physical activity
Recommendations for a healthy diet: expected growth spurt appetite surge, content similar to adult recommendations, considerations for athletes
screen for risk eating patterns for obesity and eating disorders (anorexia nervosa, avoidant restrictive food intake disorder bulimia nervosa, binge eating disorder, PICA), physical activity as per recommendations for school age children
Screening for eating disorders
SCOFF
S: do you make yourself sick because you feel uncomfortably full
C: do you worry you have lost control over how much you eat
O:have you recently lost more than one stone in a 3 month period
F: do you believe yourself to be fat when others say you are too thin
F: would you say that food dominates your life
Adolescents: safety
Violence, sports related concussion, and social media/technology
Diagnostic errors arise from
faulty knowledge, faulty data gathering, and faulty information processing
The diagnostic process
step 1: identify the problem - you must be certain that you understand what the patient is telling you
step 2: frame the differential DX (DDx)- use a problem specific framework organize the possible diseases/conditions subcategories
step 3: organize the Ddx- utilize pivotal points
step 4: limit the Ddx- Taylor Ddx using pivotal points to create a patient specific DDx
step 5: explore possible diagnoses using H and P findings- look for clinical clues that point toward the most likely Dx and fingerprint findings
step 6: rank the DDx- possibilistic approach, probabilistic approach, prognostic approach, and pragmatic approach
step 7: test your hypotheses
step 8: re rank the DDx based on new data
step 9: test the new hypothesis
Possibilistic approach
emphasizes human agency, choice, and potential outcomes over strict environmental or statistical determinism
Probabilistic approach
treats diagnosis, prognosis, and treatment as matters of likelihood rather than absolute certainties
prognostic approach
predicts the future course, progression, and outcome of a disease or health condition using individual patient data
pragmatic approach
focuses on practical, real-world solutions that work in routine clinical care rather than relying solely on ideal conditions