Domains Important in Transcription Factors like GAL4

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4 Terms

1
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What structural domains are found in transcription activators such as GAL4?

They contain a DNA-binding domain and one or more activation or repression domains.

2
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What is the function of the DNA-binding domain in GAL4?

It recognizes and binds specific sequences in the promoter or enhancer regions of target genes.

3
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What is the function of the activation domain in GAL4?

It interacts with co-activators or the transcriptional machinery to promote RNA polymerase II binding and initiation.

4
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Why are transcription factors considered modular?

Their domains can function independently and can often be swapped between different transcription factors to create chimeric regulators.