Contains polar (hydrophilic) and non polar (hydrophobic) regions. ex: phospholipids
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Phospholipid bilayer
Consists of two layers of phospholipids with the hydrophobic tails on the inside. Allow non-polar particles to enter, but often bounces out polar particles.
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Structure of Membrane
Contains phospholipids, channel/transport proteins, steroids (carbs), and proteins
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Factors affecting membrane fluidity
Unsaturated lipids prevent packing and keep it fluid. Saturated lipids allow it to pack together, making it viscous. Cholesterol buffers fluidity and prevents it from being too fluid/viscous
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Peripheral proteins
Proteins bound to membrane surface
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Integral proteins
Hydrophobic core of the membrane
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Transmembrane proteins
Span the whole membrane
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Functions of membrane proteins
Transport, enzymatic activity, signal transduction, cell-cell recognition, intracellular joining, attatching to ECM and cytoskeleton
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Glycolipid
Carb bounded to lipid
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Glycoprotein
Carb bounded to protein
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Selective permeability
Some substances can cross more easily than others. exhibited by membrane. depends on both the lipid bilayer and the specific transport proteins it contains
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Transport proteins
Allow different substances to cross the membrane (embedded in membrane) involved in facilitated diffusion and active transport.
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Channel proteins
Embedded in membrane and has a hydrophilic channel that certain molecules/ions can use to move through
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Aquaporins
Special types of channel protein that helps water move through
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Ion channel
Special types of channel protein that helps ions move through
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Diffusion
Diffusion is the movement of particles of any substance so that they spread out evenly into the available space (dynamic equalibrium). move from high to low conc. (down a conc. grad) through a membrane
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concentration gradient
the region along which the density of a chemical substance increases or decreases
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osmosis
specific type of diffusion involving free water (water not clustered around another molecule)
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Passive transport
transport of a substance across a cell membrane by diffusion (facilitated or not); expenditure of energy is not required
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tonicity
is the ability of a surrounding solution to cause a cell to gain or lose water (depends on conc. of water and other solutes that can move through membrane)
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Isotonic
solution conc. is same for both, water diffuses at same rate back and forth, no net movement. normal for animal cells. makes plant cells flaccid
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hypotonic
less solute and more water. water moves/diffuses away from this area,. causes animal cells to lyse. makes plant cells turgid (ideal condition, means firm)
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hypertonic
more solute and less water. water moves/diffuses towards this area. causes animal cells to shrivel and plant cells to plasmolyse (membrane shrivels away from walls)
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osmoregulation
control of solute concentration and water balance ex: freshwater protists using contractile vacuole to pump out excess water
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facilitated diffusion
transport proteins assist in moving molecules down a conc. gradient (high to low)
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gated channels
special type of ion channel that opens/closes in response to a stimulus
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active transport
transport of a substance across a cell membrane against the concentration gradient by hydrolyzing ATP into ADP for energy. all proteins involved are carrier proteins
enables cells to maintain solute concentrations that differ from the environment
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sodium pottasium pump
uses a phosphate from ATP to energize the transport of K+ into the cell and Na+ out of the cell. allows our neurons to refire
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membrane potential
Voltage across a membrane, created by differences in the distribution of positive and negative ions
inside is neg and attracts cations inside, outside is pos and wants anions outside
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electrochemical gradient
a chemical force (the ion’s concentration gradient) and an electrical force (the effect of the membrane potential on the ion’s movement) combined to drive ion diffusion across a membrane
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electrogenic pump
a transport protein that generates voltage across a membrane, storing energy that can be used for cellular work (USES ATP IN THIS PROCESS)
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proton pump
transports H+ ions out of the cell. assists in cotransport of sucrose back into the cell
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cotransport
passive transport helps provide energy to drive the active transport of another solute
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exocytosis
transport vesicles migrate to the membrane, fuse with it, and release their contents outside the cell
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endocytosis
In endocytosis, macromolecules are taken into the cell in vesicles & the membrane surrounds the material for transport into a vesicle. 3 types: phago, pino, and receptor mediated
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phagocytosis
a cell engulfs a particle by extending pseudopodia around it and packing it in a membranous sac called a food vacuole, and then fuses with a lysosome to digest the particle
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pinocytosis
molecules are taken up when extracellular fluid is “gulped” into tiny vesicles. takes in any and all substances, nonspecific
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receptor mediated endocytosis
Receptor proteins bound to specific solutes from the extracellular fluid are clustered in coated pits that form coated vesicles Emptied receptors are recycled to the plasma membrane by the same vesicle