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These vocabulary flashcards cover the major terms and concepts related to the structure, function, repair, aging effects, and common disorders of the integumentary system as presented in the provided notes.
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Skin
The largest organ of the body; protects internal tissues and organs; composed of the epidermis, dermis, and subcutaneous layer with accessory structures (glands, hair, nails).
Epidermis
The outer, avascular, keratinized stratified squamous epithelium of the skin.
Stratum basale
Deepest epidermal layer where mitosis occurs to form new keratinocytes.
Stratum corneum
Outermost epidermal layer of dead, keratin-filled cells that provides a protective barrier.
Keratin
Fibrous protein that makes skin and hair tough and waterproof.
Melanin
Pigment produced by melanocytes that determines skin color and provides UV protection.
Dermis
Thick, strong connective tissue layer beneath the epidermis; contains blood vessels, nerves, glands, and hair follicles.
Dermal papillae
Projections of the dermis that extend toward the epidermis, increasing surface area and forming fingerprints.
Areolar connective tissue
Loose connective tissue in the dermal papillary layer that supports the epidermis.
Adipose tissue
Fat tissue in the subcutaneous layer that insulates, cushions, and stores energy.
Subcutaneous layer (hypodermis)
Layer beneath the skin composed of areolar and adipose tissue; anchors skin to underlying structures.
Vernix caseosa
Waxy, whitish coating seen on newborns protecting the fetus's skin.
Sebaceous glands
Oil glands that secrete sebum to lubricate skin and hair.
Secrete sebum
Oily secretion from sebaceous glands (holocrine) that moisturizes skin and hair.
Meibomian glands
Sebaceous glands near the eyelashes that contribute to the tear film.
Ceruminous glands
Glands in the ear canal that produce earwax (cerumen).
Ciliary glands
Glands in the eyelids that provide lubrication around the eye.
Sweat glands (sudoriferous)
Glands that produce sweat; helps regulate temperature and excrete small amounts of wastes.
Eccrine glands
Sweat glands distributed widely; secrete directly onto the skin surface; main role in thermoregulation.
Apocrine glands
Modified sweat glands located mainly in the armpits and groin; release sweat into hair follicles and respond to emotional stress.
Mammary glands
Glands in the breast that produce milk.
Hair
Keratinized filament that grows from a hair follicle; consists of a shaft (above skin) and root (within follicle).
Hair follicle
Sac in the dermis from which hair grows; houses the hair root.
Shaft
Portion of hair that extends above the skin surface.
Root
Portion of hair located within the follicle.
Arrector pili muscle
Smooth muscle that raises hairs (goosebumps) in response to cold or fear.
Nails
Keratinized plates at the tips of fingers and toes that protect and aid in manipulation.
Nail root
Germinal portion of the nail under the skin that produces new nail cells.
Nail plate
Visible, hard, keratinized nail body.
Lunula
Whitish crescent area at the base of the nail indicating new nail growth.
Cuticle
Fold of skin (eponychium) at the base of the nail that protects the nail matrix.
Mammary glands (revisited)
Specialized sweat glands in the breast that produce milk after pregnancy.
Absorption
Uptake of substances through the skin (limited in the epidermis).
Excretion
Elimination of waste products through sweat and related secretions.
Vitamin D synthesis
Skin converts sunlight into vitamin D, essential for calcium absorption and bone health.
Protection against dehydration
Water-retaining barrier of the skin that minimizes water loss.
Barrier to invasion of pathogens
Physical and chemical barrier preventing entry of microbes.
Exfoliation
Shedding of outer skin cells to remove pathogens and debris.
Vasodilation
Widening of blood vessels to increase blood flow and promote heat loss.
Vasoconstriction
Narrowing of blood vessels to reduce blood flow and conserve heat.
Radiation of heat from surface
Loss of body heat from the skin to the surrounding environment.
Evaporation of sweat
Cooling mechanism from sweat evaporating off the skin.
Nerve endings for pain, temperature
Sensory nerves in the skin that detect pain and temperature changes.
Sensory receptors for touch and pressure
Receptors (e.g., Merkel, Meissner, Pacinian) that detect touch and pressure.
Hemoglobin
Oxygen-carrying protein in red blood cells; contributes to skin color (red/pink tint when well-oxygenated).
Carotene
Yellow-orange pigment from diet and skin storage, contributing to skin tone.
Bile pigments
Pigments (e.g., bilirubin) from liver; can tint skin yellow in jaundice.
Inflammation
Immediate wound-healing response with redness, heat, swelling, and pain.
Blood vessel formation (angiogenesis)
Growth of new blood vessels to supply healing tissue.
Fibroblasts produce collagen
Fibroblasts synthesize collagen to form scar tissue during healing.
Stem cells activated
Stem cells participate in tissue regeneration during repair.
Scar formation
Replacement of damaged tissue with fibrous tissue, restoring integrity but not original structure.
Keloids
Excessive scar tissue that extends beyond the wound margins.
Wound care
Care practices to promote healing: cleansing, infection control, and moisture balance.
Cleansing
Cleaning the wound to remove contaminants and debris.
Moisture balance
Maintaining appropriate moisture levels to support healing.
Nutrition
Adequate nutrients support tissue repair and immune function.
Blood supply (in healing)
Adequate blood flow delivers oxygen and nutrients necessary for repair.
Infection
Presence of pathogenic microbes that can delay healing.
Age
A factor that can slow healing due to reduced cell activity and circulation.
Loss of elastic fibers, fat, and collagen
Common aging changes leading to weaker skin structure and sagging.
Irregular pigmentation
Uneven skin color due to pigment changes with aging or disease.
Thinning of hair
Reduction in hair density with age or health conditions.
Loss of sweat glands
Decreased sweating with age, affecting thermoregulation.
Alopecia
Loss of hair; baldness.
Acne (overactivity of sebaceous glands)
Condition caused by excessive sebum production often with blocked follicles.
Basal cell carcinoma
Most common skin cancer; develops from basal cells; usually slow-growing.
Squamous cell carcinoma
Skin cancer arising from squamous cells; can be more invasive than basal cell.
Melanoma
Aggressive skin cancer arising from melanocytes; high risk of metastasis.
Impetigo
Bacterial skin infection causing crusted lesions; common in children.
Herpes simplex
Viral infection causing cold sores or genital lesions; recurrent.
Herpes zoster (shingles)
Reactivation of varicella-zoster virus causing painful vesicular rash.
Warts
Viral skin growths caused by HPV.
Pemphigus
Autoimmune blistering disorder causing fragile skin blisters.
Lupus erythematosus
Autoimmune disease with skin rash and systemic involvement.
Systemic sclerosis
Autoimmune disease causing skin thickening and internal organ involvement.
Psoriasis
Chronic autoimmune skin disease with scaly, inflamed plaques.
Alopecia
Loss of hair from the scalp or body.