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This JSON contains vocabulary flashcards based on the provided lecture notes on Microbiology.
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Microbiology
The study of organisms too small to be seen with the human eye.
Ga
Abbreviation for giga annum, or billion years ago, used in geochronology.
Anoxic
Without oxygen.
Prokaryotes
Microbial cells that first appeared between 3.7 and 4.2 billion years ago.
Biosignatures
Geochemical indicators of life.
Chemolithoautotroph
An organism that obtains energy by oxidizing inorganic compounds.
Stromatolites
Oldest known fossils, formed by accumulation of sedimentary layers of cyanobacterial mats.
Oxygenic Photosynthesis
Process: CO2 + H2O (plus sunlight) --> CH2O + O2.
Thermophilic
Heat-loving.
Geomicrobiology
The interdisciplinary study of the interactions of microorganisms and earth materials.
Longitudinal Cohort Study
A research study that follows large groups of people over a long time to compare a particular outcome between groups differing by a certain characteristic.
Nonillion
10^30 (1,000,000,000,000,000,000,000,000,000,000)
Phylogeny
Shows evolutionary history and relationships among individuals or groups of organisms.
Species
A group of organisms capable of interbreeding and producing fertile offspring (traditional definition); a group of closely related isolates or strains (microorganisms).
Strain/Isolate
A subgroup within a species; operational taxonomic unit (OTU).
Serotype
Distinct variations within a species of bacteria based on major surface antigens.
OTU
Operational taxonomic unit; an operational definition used to classify groups of closely related individuals.
Commensal Organisms
Beneficial microbes also termed normal microbiota or normal flora.
Pathogens
Microbes that damage body tissues and cause disease symptoms.
LUCA
Last universal common ancestor of all cells.
LECA
Last eukaryotic common ancestor.
Metagenomic Data
Analysis of whole-community genomic data.
Animalcules
Term used by Anthony van Leeuwenhoek describe microorganisms.
Endospore
A heat-resistant life-form inside of bacteria.
Miasma
Bad air - a widely accepted theory for what causes diseases such as cholera.
Viroids
Consist only of RNA; no protein coat. Obligate intracellular agents that use the machinery and nutrients of host cells to replicate.
Prions
Consist only of protein; no DNA or RNA. Misfolded versions of normal cellular proteins that cause the normal versions to misfold.
Domain Bacteria
Single-celled prokaryotes with peptidoglycan in their cell walls, multiply via binary fission, and many move using flagella.
Domain Archaea
Prokaryotic, similar to bacteria in shape and size, but lack peptidoglycan in cell walls and have different ribosomal RNA sequences; many are extremophiles.
Domain Eukarya
Eukaryotes with membrane-bound nucleus and other organelles; includes fungi, algae, protozoa, and helminths.
Algae
Diverse group of single-celled or multicellular photosynthetic organisms.
Protozoa
Diverse group of single-celled complex eukaryotes.
Helminths
Parasitic multicellular worms.
Phytoplankton
Greek: phytos – plant, planktos – wanderer, drifter; autotroph: uses CO2 as main carbon source.
Fungi
Diverse group of eukaryotes, including unicellular yeasts and multicellular molds.
Mycology
The study of fungi.
Heterotroph
Obtains carbon and energy from organic sources.
Arthropods
Invertebrate animals with segmented bodies, hard exoskeletons, and jointed appendages (e.g., insects, ticks).
Nematodes
Roundworms, a phylum of worms with cylindrical bodies.
Virus
Acellular infectious agent consisting of nucleic acid surrounded by a protein coat.
Bacteriophage
A virus that infects bacteria; also called a phage.
Obligate Intracellular Parasites
Cannot multiply unless they invade a host cell; viruses are obligate intracellular parasites.
Prion
Infectious protein particle.
Bioremediation
Using microorganisms to degrade or detoxify pollutants.
Infectious Disease
A disease caused by a microbe that can be transmitted from one host to another.
Pathogenicity
The ability of a microorganism to cause disease.
Virulence
The degree of pathogenicity of a microorganism.
Normal Microbiota (Normal Flora)
The population of microorganisms that normally grow on the body surfaces of healthy individuals.
Prevalence
The total number of cases of a disease in a given population at a specific time or period.
Emerging Infectious Diseases (EIDs)
The emergence of new diseases, increasing in incidence, or showing a potential to increase in the near future.
Septicemia
Disease-causing microorganisms present in the blood.
Localized Infection
An infection confined to a specific area of the body.
Systemic Infection
An infection that has spread throughout the body.
Virulence Factors
Mechanisms (e.g., capsules, enzymes) used by pathogens to cause disease.
Load
The relative number of microorganisms; relates to the amount of contamination.
Healthcare-Associated Infection (HAI)
An infection acquired during a stay in a healthcare facility.
Adherence
The ability of a microbe to adhere to host cells or tissues.
Commensalism
A relationship in which one organism benefits and the other is unaffected.
Mutualism
A relationship in which both organisms benefit.
Parasitism
A relationship in which one organism benefits at the expense of the other.
Infection
The replication of a pathogen in a host.
Disease
An infection that causes signs or symptoms.
Sign
Objective indication of disease that can be measured/observed (e.g., fever, rash).
Symptoms
Subjective indication of disease that is felt by patient (e.g., pain, nausea).
Case Fatality Rate (CFR)
Proportion of deaths among individuals infected with a specific disease.
Incubation Period
Time between infection and the appearance of signs and symptoms.
Latent Infection
Infection in which the infectious agent is present but not active.
Carrier
A person showing no signs or symptoms of a disease but who sheds infectious agents.
Reservoir
Natural habitat of a pathogen.
Zoonosis
A disease primarily found in animals but transmissible to humans.
Vertical Transmission
Transfer of a pathogen from a pregnant woman to the fetus, or from a mother to her infant during childbirth or breastfeeding.
Horizontal Transmission
Transfer of a pathogen from one person to another through contact, ingestion of food or water, or via a living organism (vector).
Fomite
Inanimate object that can transmit infectious agents.
Vector
Living organism that transmits infectious agents.
Biofilms
Structured communities of microorganisms attached to a surface and encased in a self-produced matrix.
Quorum Sensing
Cell-to-cell communication process in bacteria that enables them to coordinate their behavior.
Antimicrobial Resistance (AMR)
The ability of microorganisms to withstand the effects of an antimicrobial drug.
Antibiotic
A medicine that inhibits the growth of or destroys bacteria.
Sterilization
The process of making something free from bacteria or other living microorganisms.
Disinfection
The process of cleaning something to destroy harmful microorganisms.
Antiseptic
A substance that prevents the growth of disease-causing microorganisms.
Aseptic Technique
A procedure performed under sterile conditions.
Gram Stain
A staining technique for the preliminary identification of bacteria.
Acid-Fast Stain
A differential stain used to identify acid-fast organisms such as Mycobacterium.
Capsule Stain
A staining method used to visualize the capsules surrounding certain bacteria.
Bioremediation
Using microorganisms to degrade or detoxify pollutants.
Infectious Disease
A disease caused by a microbe that can be transmitted from one host to another.
Pathogenicity
The ability of a microorganism to cause disease.
Virulence
The degree of pathogenicity of a microorganism.
Normal Microbiota (Normal Flora)
The population of microorganisms that normally grow on the body surfaces of healthy individuals.