people and their contributions only
Father of Microbiology, Microscope
Antonie van Leeuwenhoek
Vaccination to establish immunity to small pox
Edward Jenner
identified organs by their types of tissue
Marie Francois Xavier Bichat
produced disease in worms by injection of organic material
Agostino Bassi
produced immunity to rabies
Louis Pasteur
demonstrated that surgical infections are caused by airborne organisms
Joseph Lister
Presented the first pictures of bacilli (anthrax) and later tubercle bacilli
Robert Koch
Described phagocytes in blood and their role in fighting infection (called phagocytosis)
Elie Metchnikoff
Distinguished blood groups through the development of the ABO blood group system
Karl Landsteiner
Discovered microorganisms whose range lies between bacteria and viruses called “rickettsiae”
Howard Ricketts
Hepatitis B Vaccine
Baruch Samuel Blumberg
Polymerase Chain Reaction
Kary Mulis
Used microscope to document the existence of cells
Robert Hooke
introduced a method of obtaining specimens for microscopic study
John Hill
studied the great cholera outbreak in London
John Snow
Developed methods of drying and fixing blood smears using heat
Discovered mast cells and classified white blood cells according to its granulation
Paul Ehrlich
Penicillin (paramount in initiating the antibiotic era)
Alexander Fleming
Developed an achromatic microscope and introduced dark-field microscopy
Joseph Jackson Lister
Prepared the first synthetic dye
William Perkin
Developed the first visual colorimeter based on Beer’s Law
Jules Duboscq
Invented the nephelometer (an instrument for measuring the size and concentration of particles suspended in a liquid or gas, especially by means of the light they scatter)
Theodore Richards
Discovered the reciprocal relationship between pH and oxygen content of hemoglobin (Bohr effect)
Christian Bohr
Invented the fluorescence microscope
Oskar Heimstadlt
Developed the colorimeter-nephelometer
Philip Adolf Kober
developed the mass spectrograph
Francis William Aston
published the first edition of diagnosis by laboratory methods
Arthur Sanford & James Todd
developed moving boundary electrophoresis of proteins
Arne Tiselius
determined the molecular weight of hemoglobin by ultracentrigufation
Theodore Svedberg
introduced the use of light colorimetry
Otto Folin
introduces Westgard control rules into clinical laboratory quality control
James Westgard
Pap smear
George Nicholas Papanicolaou