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what are the 3 major functions of the digestive system
acquisition, digestion and absorption of nutrients
why are absorbed nutrients important
they provide energy (ATP) and building material for the body
which nutrients provide the most energy per gram
fat (9kcal/g)
how many kcal per gram do carbohydrates provide
4 kcal /g
how many kcal per gram do proteins provide
4 kcal/g
what is digestion
breakdown of food into smaller molecules
what is mechanical digestion
physical breakdown of food
gives examples of mechanical digestion
chewing and stomach mixing
why is mechanical digestion important
increases surface area for enzymes
what is chemical digestion
enzyme breakdown of molecules
what is absorption
movement of nutrients into blood or lymph
list the 4 GI layers
mucosa, submucosa, muscularis externa, serosa
what are the 3 layers of the mucosa
mucous membrane, lamina propria, muscularis mucosae
what cells are found in the mucous membrane
enterocytes, goblet cells, endocrine cells
what do goblet cells secrete
mucus
what does the lamina propria contain
blood vessels, lymphatics, nerves, peyers patches
what is the function of muscularis mucosae
mixes food and increase contact for absorption
what plexus is located in the submucosa
meissner’s plexus
what plexus is in the muscularis externa
myenteric (auerbachs) plexus
what digestion occurs in the mouth
mechanical digestion and carbohydrate digestion
which enzyme begins carbohydrate digestion
salivary amylase
what are the functions of saliva
lubrication, taste, carbohydrate digestion
how does food move through the esophagus
peristalsis
what are the three stomach regions
fundus, body, antrum
which cells produce HCI
parietal cells
what are the functions of HCI
kills microbes, activates pepsin, dissolves food
which cells produce intrinsic factor
parietal cells
why is intrinsic factor important
vitamin b12 absorption
what converts pepsinogen into pepsin
hydrochloric acid (HCI)
what does pepsin digest
proteins
which cells produce mucus
mucous cells
why is mucus important
protects stomach lining from acid
which hormone is released in the stomach
gastrin
what does gastrin do
increases acid secretion and stomach contractions
where dies the most digestion occur
small intestine
where does most absorption occur
small intestine
what does the pancreas release
amylase, proteases, lipase, nucleases, bicarbonate
why is bicarbonate released
neutralizes stomach acid
what do villi do
increases surface area
peptides become what
amino acids
disaccharides become what
monosaccharides
where do carbohydrates enter
blood
where do amino acids enter
blood
where do fats enter
lymph
main function of large intestine
water reabsorption
what else is absorbed in the large intestine
salts
what do intestinal bacteria do
produce vitamins and digest some carbohydrates
function of rectum
stores feces
function of anus
eliminate feces
which organs are accessory digestive organs
salivary glands, liver, gallbladder, pancreas
function of liver
produces bile, bicarbonate, plasma proteins, cholesterol metabolism
function of gallbladder
store and concentrates bile
function of pancreas
produces digestive enzymes and bicarbonate
what is peristalsis
wave like contractions that move food
which muscles produces peristalsis
circular and longitudinal smooth muscle
why is mechanical digestion important if enzymes do chemical digestion
it increases food surface area, allowing enzymes to work more efficiently
why is bicarbonate released into the small intestine
to neutralize acidic chyme from the stomach so pancreatic enzymes can function
why are villi essential
they greatly increase surface area for nutrient absorption
why do fats enter the lymphatic system instead of the blood initially
they are packaged into large particles (chylomicrons) that enter lymph before reaching the blood stream
why is intrinsic factor clinically important
without it, vitamin B12 cannot be absorbed, leading to deficiency