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NATURAL
also known as regular insulin
Lispro
rapid acting insulin that has a brand name of Humalog that affects 15-20 mins and peaks at 1 hr
clear
rapid acting is formulated as clear or cloudy?
Lispro (HUMALOG)
Aspart (Novolog)
Glulisine (Apidra)
rapid acting insulin meds
Glulisine (clear)
rapid acting insulin (Apidra) is a synthetic analog of natural insulin with rapid onset of 15-20 mins
Regular Insulin
also known as slower acting, which is also made pf clear formulation
30-1 hr
start of effect of regular or slow acting insulin is?
2-4 hrs
hrs of peak of regular insulin, where the pt with diabetes near hypoglycemic and need to eat food.
novolin R, and Humulin R
drugs under the regular acting insulin drugs
clear
what is the formulated solution of regular insulin clear or cloudy?
regular insulin
it is also known as semilente
Netral Protamine Hagedron (NPH) insulin
Intermediate Acting insulin
short acting
intermediate acting or NPH insulin is only suitable to be mixed with what classification of clear insulin
cloudy
the formulation of NPH insulon is clear or cloudy?
Humulin N
Novolin N
Intermediate Acting/ NPH (cloudy insulins) brand names
2-4 hrs- 4-8 hrs
start of effect and peak time of the NPH
isophane insulin
Novolin N is also known as
regular insulin is fast acting and nph is long acting (like Tetanus Toxoid) regular controls post meal rise in blood sugar while waiting for the NPH (2-4 hrs) to take effect to prevent postprandial hyperglycemia
why NPH is usually administered with regular insulin
to control postprandial hyperglycemia
why NPH alone cannot be administered at mealtime
NPH and regular insulin
Insulin that are available without prescriptions are
Glargine (Lantus)
very long duration insulin that is modified human insulin with a prolonged duration of action upto 24 hrs, unlike other insulin that has peak time that fall thru hypoglycemia, this achieves blood levels that are relatively steady,
clear
very long acting insulin Glargine has a formulation of clear or cloudy?
subq
very long acting insulin should be given on what route and never on IV
Detemir (Levemir)
Insulin that is very long acting that persists or take affect about 12 hrs and persist up to 20-24 hrs and available by prescription only and must not be given IV
Degludec (Tresiba)
other form of very long acting insuin with brand namesre
regular, lispro, aspart, and glulisine
insulins available as clear solutions and only that can be administered IV
air:cloudy- clear- drawl; clear-cloudy
how to prepare the insulin
1 hr
onset time of very long acting insulins
4-8 hrs 8-16
onset time for long acting insulin and the peak
frothing
what will happen if you over mixed in vigorous agitation the insulin
lypodystrophy
Insulin drugs must be stored in “room temp” to prevent change in fat tissue that can lead to poor insulin absorption
get first the long acting before short
how to prepare insulin if both are clear
if closed- refrigerate
if open- store in room temp
how will you store the insulin
last for 28 days
how long the open insulin lasts before discarding