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Nuclear Membrane - 3 Layers
Outer
Inner
Nuclear lamina
ER - 2 Specific Functions
Control disulphide bonding + glycosylation
Ca storage
Rough ER
Entry secretory pathway
Golgi
Vesicle from ER
Enter cis
Cisternae - modify + sort + mature
Exit trans
Vesicles - secretory + lysosome
Lysosomes - pH
4.5-5
Lysosomes - Process
Activate zymogens
Acid hydrolases
Hydrolysis
Mitochondria - Membrane
Outer - highly permeable
Inner - cristae
Mitochondria - Function
Generate proton motive force
Own genome
Endosymbiotic Theory
Anaerobic primitive archaeon
Enguld aerobic bacterium
Symbiosis - energy vs protection/nutrients
Mitochondria - circular independent DNA (bacteria like)
Peroxisomes - b-oxidation
Break down fatty acids
Produce H2O2
Catalase detoxify
Lipid Droplet - 3 Components
Neutral lipid core - TAG + SE
Phospholipid monolayer
Perilipin proteins