fluid therapy pharm lecture 3

total body water is

60% of weight

intracellular fluid is

2/3 of TBW

extracellular fluid is

1/3 TBW

interstitial fluid is

¾ ECF

Plasma is

¼ ECF

The glycocalyx controls

movement between plasma and interstitial space

The starling equation tells us

about fluid filtration from the capillary to the outside and back

What are crystalloids (replacement)?

replacement fluids, very close to electrolyte content of the ECF, mainteinance fluids, short vascular volume expansion

Crystalloid content (replacement)

high in Na and low in K

Crystalloid (maintainance) contents

higher K, lower Na (not for rapid administration)

Hypertonic saline causes

salt causes water to follow pulling water from ICF

What is the best option to deliver a large volume of fluids quickly?

hypotonic saline

If we give fluid too fast what will we see?

Potentially edema