Mitochondria

cardiolipin

4 tailed lipid on inner membrane

dynamin related protein

recruited to transmembrane receptors on outer membrane

N-terminal presequence

targets proteins for mitochondrial import, 15-55 basic and hydroxylated amino acids

Tom 20/22

import receptor that binds to presequence

Tom 40

general import pore on outer membrane where bound protein passes through

Tim 23/17

pore on inner membrane where bound protein passes through

matrix Hsp70

binds protein and draws into matrix

mitochondrial processing peptidase

removes presequence

Oxa1

inserts protein into inner membrane

Tom 22/70

receptor for inner membrane bound protein

Tim9/10

intermembrane space chaperones

Tim22/18/54

Tim translocon

Mia 40

disulfide transfer protein

Erv1

disulfide bond generating protein

SAM

inserts beta barrels in the outer membrane

Mim1

inserts alpha helices in the outer membrane