Amino Acids

0.0(0)
Studied by 0 people
call kaiCall Kai
Locked
learnLearn
examPractice Test
spaced repetitionSpaced Repetition
heart puzzleMatch
flashcardsFlashcards
GameKnowt Play
Card Sorting

1/18

encourage image

There's no tags or description

Looks like no tags are added yet.

Last updated 3:01 PM on 7/21/26
Name
Mastery
Learn
Test
Matching
Spaced
Call with Kai
Chat

No analytics yet

Send a link to your students to track their progress

19 Terms

1
New cards

Traits

Structure Impacts Function

Amino Acid Patterns Determine Structure

Core - Hydrophobic (Nonpolar)

Surface - Hydrophilic (Polar)

2
New cards

Amino Acid Structure

COOH, H, H2N, R

3
New cards

Electronegativity Difference and Polarity

O, N, - Polar

O-H - Non Polar

C - H - Non Polar

4
New cards

Six Polar Neutral Amino Acids

Santa’s Team Crafts New Quilts Yearly

Ser, Thr, Cys, Asn (Y), Gln (Q), Tyr (Y)

<p>Santa’s Team Crafts New Quilts Yearly</p><p>Ser, Thr, Cys, Asn (Y), Gln (Q), Tyr (Y)</p>
5
New cards

Phosphorylation

Targets the -OH

Kinase = Phosphorylation with ATP

Phosphorylation changes structure by adding negative to the surface. In return changing function

Phosphomnetic Effect

SYT

Ser, Tyr, Thr

<p>Targets the -OH</p><p>Kinase = Phosphorylation with ATP</p><p></p><p>Phosphorylation changes structure by adding negative to the surface. In return changing function</p><p></p><p>Phosphomnetic Effect</p><p></p><p>SYT</p><p>Ser, Tyr, Thr</p>
6
New cards

Disulfide Bonds (THIOLS)

SDS-PAGE

Only form from 2 Cys residues

Reduction breaks the bridge (Intra/Inter)

7
New cards
<p>Asp (N) and Glu (Q): AMIDES</p>

Asp (N) and Glu (Q): AMIDES

Glu has extra carbon

8
New cards

Non Polar (C-H) (C-C)

Aliphatic Amino Acid

Non Aromatic, Hydrocarbon Tails

Glaciers In Alaska Valiantly Locate Isolated Prowlers.

<p>Non Aromatic, Hydrocarbon Tails</p><p>Glaciers In Alaska Valiantly Locate Isolated Prowlers.</p>
9
New cards

Branched Amino Acids

Leucinezc Isolleucine, Valine

10
New cards

Aromatic Aminos

Phenylalaninine, Tyr, W

My wife’s aroma.

11
New cards
term image
12
New cards

Acidic Amino Acids

Neg Charge, due to (COO-)

Aspartate (D) and Glutamate (E)

Asp, Glu

At pH 7.4, pka is 4.

DE

<p>Neg Charge, due to (COO-)</p><p>Aspartate (D) and Glutamate (E)</p><p>Asp, Glu</p><p>At pH 7.4, pka is 4.</p><p>DE</p><p></p>
13
New cards

Basic Side Chains

Carry positive charge

Lysine (H) , Arginine (R), Histidine (H)

KRH (Knights Riding Horses)

10, 12.5, 6 = pka

H is only partly pronated in the bottom/interior

<p>Carry positive charge</p><p>Lysine (H) , Arginine (R), Histidine (H)</p><p>KRH (Knights Riding Horses)</p><p>10, 12.5, 6 = pka</p><p>H is only partly pronated in the bottom/interior</p>
14
New cards

Heterocycles

Imidazole (2N) sits on histidine

Indole (1N) on tryptophan

NOT:

Benzene (Phe)

Phenol (Tyr)

15
New cards

Henderson - Hasselbalch

pH = pKa + log ([A-]/[HA])

PH = A / The Environment

PKA = HA / The Molecule

16
New cards
<p>Typical pKa values</p>

Typical pKa values

Cysteine - 8

Tyrosine - 10

Carboxylic acids get charge when deprotonated .

17
New cards

Acidity of the whole molecule

Isoelectric point = where the charge is zero (zwitter ion)

PI represents all molecules

pi>ph (molecule wins)

ph>pi (env wins)

18
New cards

How to calculate the pI

Average of pKa = pI

  • For an amino acid: avg the two lower pKa’s for an acidic amino acid, and the two higher pkas for a basic amino acid.

carboxylic acid ph = 2

amino acid ph = 9

side chain ph depends on R

increasing pI = more basic

<p>Average of pKa = pI</p><ul><li><p>For an amino acid: avg the two lower pKa’s for an acidic amino acid, and the two higher pkas for a basic amino acid.</p></li></ul><p></p><p>carboxylic acid ph = 2</p><p>amino acid ph = 9</p><p class="p1">side chain ph depends on R</p><p class="p1"></p><p class="p1">increasing pI = more basic</p><p></p>
19
New cards

Isoelectric focusing: separate by pI

anode +

cathode -