Chapter 19

Genomic DNA is replicated during which of the following cell-cycle phases?

S

In an adult human stem cell that has a total of 48 chromosomes, how many chromatids are present at prophase of mitosis?

96

Dividing adult eukaryotic cells spend most of their time in which of the following?

interphase

The cell-cycle phase that varies most in duration in various eukaryotic adult cell types is

G1

Chromosome condensation indicates a cell has entered

Prometaphase

Each of the following is true about anaphase except

All of the above are true

Each of the following is an activity of a microtubule motor protein during mitosis except

All of the above are activities of microtubule motors

Each of the following is involved in plants cell cytokinesis except

abscission of the cell into two cells

In the cell cycle, a mitotic Cdk is present during

All of the above phases.

When early G1 phase cells are fused with S-phase cells using polyethylene glycol (PEG), which of the following events would you expect to be induced?

DNA replication in the G1 cells

Cyclins modulate the progression of cells through the cell cycle by directly

activating protein kinases that are critical regulators of cell division.

A eukaryotic cell G2-M checkpoint assesses the status of

DNA replication.

Which of the following is eliminated in rapidly dividing embryonic cells that get smaller with each cell division?

G1 phase

Each of the following is involved in regulating mitotic Cdk activity except

Cdk synthesis and degradation.

Each of the following is involved in DNA replication licensing during S phase except

CENP-A.

The epidermal growth factor-Ras signaling pathway stimulates increased expression of each of the following except

MAPK.

A protein on the surface of cytotoxic lymphocytes can elicit self-destruct mechanisms in target cells by interacting with

Death receptors.

All of the following participate in apoptosis except

APC ubiquitin ligase activity.

Each of the following involves apoptosis except

generating a cancerous tumor.

The mechanism by which DNA is licensed to replicate only once during each S phase involves

MCM proteins binding only to nonreplicated DNA.