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What are the 3 main parts of the brainstem?
Midbrain, pons, medulla
What does the brainstem do with information?
Carries all information between the brain and the remainder of the body
What is the brainstem the corridor to?
All the major sensory, motor, cerebellar, and cranial nerve pathway
The brainstem has nuclei that do what?
That control cranial nerves, consciousness, muscle tone, posture, and vital functions
What can small lesions in the brainstem cause?
Small lesions can result in substantial deficits
What nerves do not emerge from the brainstem?
CN I Olfactory and CN II Optic nerves connect directly to the forebrain
Where do the olfactory nerves (CN1) enter?
They enter the olfactory bulbs and olfactory tracts that run along the ventral frontal lobe
How do the nerves exit the brainstem?
The foramina
Where do the optic nerves meet?
They meet at the optic chiasm forming the optic tracts
What are nuclei?
Clusters of nerve cells
How are the brainstem nuclei organized?
2 columns motor and sensory with 3 nuclei in each
Where are the motor columns located?
Closer to the center
What are the 3 nuclei in the motor column?
Somatic motor, branchial motor, and parasympathetic
What is the function of the Somatic motor nuclei?
Extraocular muscles and intrinsic tongue muscles
What is the function of the branchial motor nuclei?
Muscles in the face, jaw, and neck (including larynx)
What is the function of the parasympathetic nuclei?
Glands, smooth muscles, and cardiac muscles
Where are the sensory columns located?
Toward the outsides
What are the 3 nuclei in the sensory column?
Visceral sensory, general somatosensory, special somatic sensory
What is the function of the visceral sensory nuclei?
taste, cardiorespiratory, and digestive functions
What is the function of the general somatosensory nuclei?
Basic touch, pain, temperature, vibration sense for face, sinuses, and meninges
What is the function of the special somatic sensory nuclei
Olfaction, vision, hearing, balance (vestibular sense), and taste
What are the benefits of the brainstem nuclei having a columnar layout?
Allows the brainstem to efficiently process multiple types of information simultaneously and keeps related functions grouped together
What cranial nerves are purely motor?
CN III, IV, VI, XI, XII
What cranial nerves are both motor and sensory?
CN V, VII, IX, X
What cranial nerves are purely sensory?
CN I, II, VIII
What is the function of the olfactory nerve?
Olfaction, nose to brain
What is the olfactory nerve CN I process?
Stimuli are detected by chemoreceptors on sensory neurons → axons travel the olfactory nerves to synapse in the olfactory bulbs → from the bulbs info. travels via the olfactory tracts to neural processing areas
What can happen when things go wrong in the olfactory nerve CN I?
anosmia - olfactory loss
How can you acquire anosmia?
Congenital (from birth) or acquired through head trauma, viral infection (like COVID), and brain damage
What is the function of the optic nerve CN II?
Vision
What is the optic nerve CN II process?
The retinal ganglion cells (start of the optic nerve) carry info. to the optic chiasm which carries info. to the optic tract which carries info to the neural processing areas (LGN, occipital lobe, etc.)
What is the function of the oculomotor nerve CN III?
Pupil constriction and move eye upward
What is the function of the trochlear nerve CN IV?
Move eye inward and down
What is the function of the abducens nerve CN VI?
Move eye out - away from nose
What sort of path/highway are the nerves that have to do with eye movement?
One way highway - brain to muscles
What is oculomotor nerve palsy?
Oculomotor nerve CN III damage, abnormal eye movement towards nose, may lie in a “down and out” position at rest
What is abducens nerve palsy?
Abducens nerve CN VI damage, abnormal movement away from nose - can cause “lazy eye”
What is the sensory function of the Trigeminal nerve CN V?
Provides sensory innervation to the face (facial sensation not expression), touch, pain, temp, joint position, vibration of part of tongue + nasal sinuses + meninges
What is the motor function of the Trigeminal nerve CN V?
Controls jaw (mastication) muscles
What are the 3 branches of the Trigeminal nerve CN V?
Ophthalmic decision (V1), maxillary division (V2), and mandibular division (V3)
What is the sensory component of the Ophthalmic division (V1) of the Trigeminal nerve CN V?
sensation for forehead, upper eyelid, scalp, and nose tip → like feeling a headband across your forehead
What is the sensory component of the Maxillary division (V2) of the Trigeminal nerve CN V?
Sensation cheek, upper lip, upper teeth/gums, nose sides → feeling the wind on your cheek or pain from an upper tooth cavity
What is the sensory component of the Mandibular division (V3) of the Trigeminal nerve CN V?
Sensation lower jaw, lower lip, lower teeth/gums, chin, part of ear → feeling your chin rest in your hand
Upper motor neuron control reaching the trigeminal motor nucleus is predominantly ___ ?
bilateral
In relation to the Trigeminal nerve CN V, unilateral lesions cause what?
Nothing - usually no deficits
What is the main function of the facial nerve CN VII?
To control the muscles of facial expression
What does the branchial motor component of facial nerve CN VII do
Controls facial expression and middle ear muscles
What are the 3 sensory components of the facial nerve CN VII?
Parasympathetic, visceral sensory, and general somatosensory
What is the role of the parasympathetic sensory component of the facial nerve CN VII?
Tears and salivation
What is the role of the visceral sensory component of the facial nerve CN VII?
Taste (from chemoreceptors to the brain)
What is the role of the general somatosensory component of the facial nerve CN VII?
External ear (touch, pain, and temperature)
What is Bell's palsy?
The divisions of facial nerve CN VII are impaired within a few hours or days, and then gradually recover → cause is unknown
What are the 2 pathways in the vestibulocochlear nerve CN VIII?
Vestibulo (balance and rotation) and the cochlear (hearing)
What is the function of the vestibulo component of the nerve CN VIII?
Rotation and acceleration transduced in inner ear
What is the function of the cochlear component of the nerve CN VIII?
Sound vibration transduced from physical to electrical energy in inner ear
What are the 3 sensory components of the glossopharyngeal nerve CN IX?
General somatic, visceral somatic, general visceral
What is the role of the general somatic component of the glossopharyngeal nerve CN IX?
Sensation from middle ear, back ⅓ of tongue, and back of throat
What is the role of the visceral sensory component of the glossopharyngeal nerve CN IX?
Taste from back ⅓ of tongue (especially bitter)
What is the role of the general visceral sensory component of the glossopharyngeal nerve CN IX?
Conveys inputs from baroreceptors and chemoreceptors in the carotid body (including blood and oxygen levels)
What are the 2 motor components of the glossopharyngeal nerve CN IX?
Branchial motor and parasympathetic
What is the role of the branchial motor component of the glossopharyngeal nerve CN IX?
Swallowing assistance
What is the role of the parasympathetic component of the glossopharyngeal nerve CN IX?
Saliva production
What is glossopharyngeal neuralgia?
A rare disorder that causes severe intense pain in the throat, tongue, tonsils, and ear
What is the role of the general somatic sensory component of the vagus nerve CN X?
Sensation for the small area of outer ear
What is the role of the general visceral sensory component of the vagus nerve CN X?
Sensation for abdominal pain and thoracic organs (blood chemistry, pressure, pain)
What is the role of the special visceral sensory component of the vagus nerve CN X?
Taste from epiglottis and pharynx
What is the role of the branchial motor component of the vagus nerve CN X?
Pharyngeal muscles (swallowing) and laryngeal muscles (voices)
What is the role of the parasympathetic component of the vagus nerve CN X?
“Rest and digest” - cardiovascular function, respirations, and digestion
What is the function of the spinal accessory nerve CN XI?
Turning head to opposite side (tilting head) and upper trapezius (movement and stabilization of scapula and upper limb movement- elevating the shoulder)
What is the function of the hypoglossal nerve CN XII?
Tongue intrinsic (in the tongue) and extrinsic (attached to the tongue) muscles → speech swallowing process, food manipulation in the mouth