The study of how the body's normal processes change when we get sick or injured.
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Pain
An unpleasant, uncomfortable sensation usually indicating tissue damage.
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Somatosensory component
Part of the nervous system that provides awareness of body sensations such as touch, temperature, limb position, and pain.
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Specificity theory
The theory that predicts the level of pain of a specific acute injury but does not encompass the subjective experience of pain.
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Pattern theory
A group of theories proposing that pain receptors share pathways with other sensory modalities, suggesting that different patterns of activity signal painful versus non-painful stimuli.
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Gate control theory
A theory suggesting that larger diameter, faster propagating fibers can inhibit the perception of pain by activating interneurons.
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Neuromatrix theory
A theory addressing the brain's role and the various determinants of pain, aiding in understanding chronic and phantom limb pain.
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Neospinothalamic tract
A pathway that provides rapid transmission of sharp, fast pain information to the thalamus.
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Palesospinothalamic tract
A slower conducting pathway that transmits sensory information associated with dull and chronic pain.
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Pain threshold
The point at which a stimulus is perceived as painful.
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Pain tolerance
The maximum intensity or duration of pain that a person is willing to endure.
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Acute pain
Self-limiting pain that lasts less than 6 months.
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Chronic pain
Persistent pain that lasts longer than 6 months, often debilitating and lacking acute pain's autonomic responses.
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Nociceptive pain
Pain arising from the activation of pain receptors in response to actual or potential tissue injury.
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Referred pain
Pain perceived at a location other than the site of the painful stimulus, often due to shared nervous system pathways.
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Endogenous analgesia
The body's intrinsic system for relieving pain through the central nervous system.
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Neuropathic pain
Pain that originates from pathology affecting the nervous system.
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Trigeminal neuralgia
A type of neuropathic pain characterized by facial tics or spasms.
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Phantom limb pain
Neurological pain following the amputation of a limb, often experienced as sensations of tingling or burning.
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Cognitive behavioral interventions
Non-pharmacologic pain management strategies such as relaxation, distraction, and biofeedback.
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Opioid analgesics
Medications used primarily for relieving moderate to severe pain.
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Morphine sulfate
A prototype opioid used for pain management, metabolized in the liver.