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Gate Control Theory
The theory that explains how the perception of pain is controlled by a gating mechanism in the spinal cord.
A Delta fibers
Nerve fibers that transmit sharp, localized pain rapidly to the central nervous system.
C Fibers
Nerve fibers that carry dull, aching pain and are slower in transmitting signals than A delta fibers.
Limbic System
Part of the brain involved in emotions and behavioral responses to pain.
Substance P
A neuropeptide that is associated with the transmission of pain signals.
Glutamate
An amino acid neurotransmitter that plays a role in pain transmission and perception.
Acute pain
A type of pain that is typically sharp and short-term, resulting from injury or illness.
Chronic pain
Pain that persists for a long duration, often lasting longer than the usual recovery time.
Neuropathic pain
Pain caused by damage to the nervous system, often described as burning, tingling, or shooting sensations.
Nocioplastic pain
Pain resulting from altered pain modulation without clear injury or inflammation.
Windup
A phenomenon where repeated stimulation of pain pathways leads to increased pain sensitivity.
Peripheral Sensitization
Increased responsiveness and reduced threshold of nociceptive neurons in peripheral tissues.
Central Sensitization
Increased sensitivity to pain due to changes in the central nervous system's processing of pain signals.
