what are the 3 important chains in the chain of infection?
source, transmission, and susceptible host
examples of infection sources?
patients (most common), visitor, staff, environment, equipment, etc.
examples of infection transmission?
contact (skin to skin), indirect contact (handling a bedpan), droplet, airborne, blood and body fluids, vectors
how far can respiratory droplets travel?
depends on size; very large about 1m, smaller droplets closer to 2m/6 feet (currently what we accept)
what are true airborne organisms?
droplet nuclei
what is a vector?
living organisms that transmits disease (ex. mosquitoes)
what factors may be make a host susceptible?
extremes in age, immunosuppression, no immunity, chronic conditions, emergency procedures
what is meant by "tip of iceberg" in regards to pathogens?
tip of iceberg: diseases we can see (ex. rash) bottom of iceberg: blood borne pathogens and stuff
what are routine practises?
recommended practises for the routine care of all patients in various setting and incorporates previous precautions against blood-borne pathogens
similar to standard precautions published by the CDC
who has current published guidelines for routine practises? year?
the provincial infectious disease advisory committee; 2012
what are routine practises determined by?
the interaction with the patient, not by the patients diagnosis -- anticipate the risk of exposure to blood and other body fluids
(don't wear gloves just because you're judging a patient)
which body fluids are considered potentially infective?
ALL body substances, of ALL substances
what are routine practices used in conjunction with?
additional precautions
what are additional precautions used for (3)?
droplet and airborne
antimicrobial resistant bacteria
organisms/ infections of significance
what is the health heirarchy of controls (5)?
elimination
substitution
engineering control (ex. negative pressure rooms)
administrative controls
PPE
what is a major way to stop transmission of infection?
hand hygiene
terminates outbreaks in health care facilities, reduce transmission of antimicrobial resistant organisms and reduce overall infection rates
what does an increase in hand hygiene by 20% result in?
a 40% reduction in the rate of HAI
bad news; most healthcare providers already believe their practicing good hand hygiene
what are the 2 main strategies for hand hygiene?
hand washing with soap and water
hand rubs with alcohol-based products (preferable in health care settings)
what are the 2 major moments where most health care providers miss hand hygiene?
2: before aseptic procedures 4: after patient/ patient environment contact
when should gloves be used?
as an additional measure (when is contact with body fluids or moist substances from exudate/wounds)
NOT a substitute for hand hygiene (use of either does not negate need for the other)
benefits of gloves?
reduce hand contamination by 70-80%, and prevent cross contamination and protect patients and health care personnel from infections
hand hygiene surrounding glove use?
before donning and after doffing
what is the point of mask, eye protection and face shield?
to protect mucus membranes during procedures and patient care activities likely to genera splashes or sprays of blood, body fluids, secretions or excretions
OR within 2 m of a coughing patient
when should gowns be worn?
when clothing is likely to be soiled; procedures likely to generate splashes/sprays of body fluid
accommodation associated with routine practises?
single room not required unless patient visibly soils environment
guidelines for equipment and routine precautions?
clean between all patients
safe sharps disposal
guidelines for environmental control surrounding routine practises?
establish routine care, cleaning of surfaces and furniture, using hospital approved disinfectant
be mindful of high tough surfaces and items
risk factors for infection after exposure to blood (4)?
pathogen involved
type of exposure
amount of blood involved
amount of virus in the blood
are hepatitis and HIV transmitted by feces, nasal secretions, sputum, tears, urine or vomit?
NO! unless they are visibly contaminated with blood
risk of contracting hepatitis B from blood exposure?
6-10%
visually no risk if vaccinated and developed immunity
risk of contracting hepatitis C (HCV) from blood exposure?
1.8 % after cut or needle stick
risk unknown following a blood splash
risk of contracting HIV after blood exposure (3)?
0.3% after needle stick or cut
0.1% after splashes to nose, mouth, eye
risk <0.1% after exposure to skin
BBP risk prevention?
hepatitis B vaccine, maintain intact skin, maintain good health
BBP risk elimination?
disinfection, safe containment of blood
BBP risk reduction?
PPE
what microbe factors should be considered when assessing risk of transmission (5)?
ability to survive in environment
low infective dose
virulence and pathogenicity
can it exist in the carrier state?
means of transmission
what patient factors should be assessed in regards to risk of transmission?
symptoms of diarrhea
requires hand on care
poor hygiene
copious respirate secretions
what patient care environment factors should be considered in regards to risk of transmission (4)?
if housekeeping is poor
equipment is shared between patients
multiple bed rooms
nurse/patient ratio (cut corners when short staffed)
what factors should be assessed in the new susceptible host regarding risk of transmission (5)?
portals of entry (catheters, skin integrity)
immune status
underlying medical conditions
antibiotic therapy
high acuity/ hands on care
what are additional precautions based on?
transmission
required when routine practices are insufficient
when might someone be put on airborne precautions (2)?
when they have pulmonary/ laryngeal TB
measles/ measles like rash
requirements for airborne precautions (4)?
single room with door kept closed
negative pressure (OR is positive)
6-9 air changes/ hour
direct exhaust -- air from room goes right outside
PPE for airborne precautions?
respirators that filter out sub micron particles and fit around contours of face to avoid air leaks
patient transport with airborne precautions?
only to leave room for essential procedures; patient to wear surgical mask
when are patients typically put on droplet?
for diseases that spread via respiratory droplets:
colds, bronchitis, bacterial meningitis, COVID, pertussis, flu, etc
accommodations for droplet precautions ?
single room is preferred (if not able, spatial separation of > 4 meters) -- in nurseries, 1-2 m between bassinets
may cohort patients with same diagnosis, and doors may be kept open
PPE for droplet precautions (4)?
surgical mask
eye wear
gown (routine practise when droplets/ splatters anticipated)
gloves (when handling respiratory secretions)
patient transport on droplet precautions?
only leave for essential services
wear surgical/ procedure mask when leaving
what are the precautions for COVID?
enhanced droplet (N95)
when is a patient placed on contact precautions?
for enteric organisms (ex. c. diff), and antibiotic resistant organisms (ex. MRSA)
PPE for contact precautions?
gown and gloves
accommodation for contact precautions?
single room preferred; assess patient, organism, and roommate when considering shared accommodation
patient transport for routine precautions?
patient should be transported in clean gown and sheet, and preform hand hygiene upon leaving the room
sequence to remove PPE (6)?
remove gloves
remove gown
hand hygiene
remove eye wear
remove N95 respirator
preform hand hygiene
general rules for a healthy workplace (2)?
do not come to the hospital if you have an acute illness that is probably of infection etiology
AND stay up to date on vaccines!!
parameters for patient and family teaching surrounding infection and prevention control?
patients: should have infections and precautionary measures explained to them
family: should understand means of transmission, risk and prevention strategies
all educational material should be clear and in layman's terms
what are some important factors in acute care to consider surrounding precautions (4)?
more acuity
skin broken
incisions
catheters, IVs, tubes
hand washing, gown and gloves all common
what are some factors to be considered in long term care settings surrounding precautions (4)?
underlying conditions
decubitus ulcers
peg tubes
partial to total care
hand washing, occasional gowns + gloves
what are some factors that should be considered in lodging homes/ senior residences surrounding precautions (3)?
higher self care level
intact skin
able to follow directions
hand washing, rare need for gown or gloves
HAI are the most common ......
serious complication of hospitalization
5-10% of patients acquire HAI
HAIs are the ____ leading cause of death in Canada.
how has this changed?
4th
11th 20 years ago
what are process indicators?
monitoring compliance with best practise (surrounding prevention of HAIs)
what is syndromic surveillance?
monitoring for new onset of symptoms such as fever, cough, SOB and or GI illness
most common HAI?
UTI
what are the different classifications of surgical wounds, and associated risk of infection (4)?
clean (ex. eye, or heart): 1-5%
clean contaminated (exposure to normal flora, such as mouth): 3-11%
contaminated (areas of inflammation): 10-17%
dirty (ex. soiled wound): >20%
what factors may increase susceptibility to an SSI (surgical site infection) (7)?
age
diabetes
immunosuppression
obesity
malnutrition
emergency surgery
duration of surgery
what are the different sources for reservoirs for microorganisms (3)?
personnel (skin, hair, anus, vagina and throat)
patient (normal flora, skin and mucus)
environment (air handling, instruments, bandages)
what are pre-op prevention strategies for SSI (5)?
showers
hair removal
skin prep
drapes
prophylactic antibiotics
what are intra-operative prevention strategies for SSI?
low OR traffic (keep doors closed)
duration of the procedure
sterile insertion of drains, catheters and IVs
appropriate attire for a safe/ sterile operation (4)?
masks, gowns, gloves, and cap
how is the environment controlled in the OR?
clean air rooms
laminar airflow rooms
what are the OR cleaning procedures (case/daily/weekly/monthly)?
between cases: horizontal surfaces, 1 m radius around OR table
daily: full floor, lights, walls
weekly: shelves, external vents
monthly: hallways and additional storage
what is IV infection risk based on (5)?
site
prep (skin and solution)
technique
daily observation (be concerned if anything strange!)
duration of IV insitu
what is the primary risk for HAI UTI?
instrumentation and catheter care
stratagies for UTI prevention?
minimize catheters (sterile technique when needed), keep bag below patients hips (prevent back flow), and select appropriate catheter.
daily peri care
what is considered nosocomial pneumonia?
not present or incubating at time of admission; no incubation within the first 48-72 hours
how is bacterial nosocomial pneumonia primarily spread (3)?
aspiration
inhalation of aerosols
hematogenous spread
what does viral pneumonia reflect?
the prevalence of virus in community; does not predominantly hit the high risk group
who does fungal and unusual bacteria primarily effect?
the immunosuppressed, and transplant cases
what role does the hospital environment play in fungal and unusual bacterial infections?
concerns such as construction, renovations and water features increase risk
what patient factors increase pneumonia risk (7)?
thoracic operations
old age (60+)
patients who aspirate
reduced ability to cough
patients having invasive procedures
colonization of some organisms
impaired immunity
examples of control measures for pneumonia?
immunization, sterile technique, oral care, precautions, etc
im not gonna list them all cuz you already know
what is the different between antiseptics/ disinfectants and sterilization?
antiseptics: used on living tissue disinfectant: used on material to remove/ climate some organisms sterilization: kills ALL microorganisms
____________________ must proceed all sterilization and disinfection
cleaning
goop is not sterile, even if sterilized
what are critical items?
items that will enter sterile body cavities, or come in contact with sterile tissue (ex: surgical clamp)
require sterilization
what are semi-critical medical devices?
items that only contact with mucous membranes or non-intact skin (ex: endoscope)
requires high level disinfection minimum!
what are non critical medical devices?
devices that come into contact with intact skin (ex. urinal)
require sanitization
what is the decontamination process?
removes blood, body fluid and tissue in order to ensure sterilization
makes items safe to handle
what are the disinfection methods? what can't it eliminate?
thermal and chemical
spores stay
what is low level disinfection?
disinfection with things like house hold cleaning products such as bleach can kill most bacteria, some viruses and some fungi (ex. TB, vegetative bacteria)
used for cleaning general patient care areas (ex. IV poles, bedside)
what is high level disinfection?
process destroying everything but bacterial spores
requires special ventilation, PPE , and specific tech
used in outpatient settings
what are the types of sterilization?
steam under pressure
dry heat
ethylene oxide gas
chemical sterilants (take 10-12 hours)
what is pasteurization?
reducing micro-organisms by thermal disinfection (ex: hot water for 30 minutes)
typically used with respiratory equipment
disposable/ single use, vs. single patient use?
disposable/ single use: one and done (discard)
single patient use: can be used repeatedly but only by the same patient