MODULE 5 MANOR DRILLS (APRIL 2024)

1. Identify the tablet that dissolves slowly in the cheeks for systemic absorption

A. Chewable tablet

B. Buccal tablet

C. Sublingual tablet

D. Orally disintegrating tablet

B

(chewable - chewed first before swallowing

sublingual - under the tongue, dissolves rapidly

orally disintegrating tablet - liquefies on the tongue [swallowed by the patient])

Determine the heat required to increase the internal energy and to perform work

A. Specific heat

B. Heat potential

C. Entropy

D. Enthalpy

D (specific heat - amt of heat per unit mass required to raise the temp by 1 C

entropy - disorder)

Select the technique for solving flavoring problems that involves the addition of a flavor whose intensity is longer and stronger than the obvious taste

A. Overshadow

B. Chemical

C. Blending

D. Physiological

A

(Overshadow - methyl salicylate, glycyrrhiza, oleoresins

Chemical - complexation/adsorption on a substrate

Blending - use of flavorants or chemicals/mixing of tastes

Physiological - taste buds are anesthetized [menthol & mint])

Which of the following is a colligative property?

A. Osmotic pressure

B. Boiling point

C. Freezing point

D. Vapor pressure

A (Boiling point - elevation, Freezing point - depression, Vapor pressure - lowering)

Compute for the required volume of water to make 0.3 g of atropine sulfate (E = 0.13) isotonic

Identify the legal terminology defined as an agreement between two or more persons engaged in the production, manufacture, processing, storage, supply, distribution, marketing, sale or disposition of products designed to artificially and unreasonably increase or manipulate its price

A. Cartel

B. Hoarding

C. Panic buying

D. Panic hoarding

A

(Hoarding - undue accumulation of products beyond normal inventor levels

Panic buying - phenomenon where consumers buy products grossly in excess

Profiteering - sale of a product that is at a price grossly in excess of its value)

Newborn Screening Act of 2004

C (RA 8049 - Anti-Hazing Act of 1995

RA 8976 - Food Fortification Act of 2000 [rice w/ iron, flour w/ Vit A and iron, cooking oil w/ Vit A]

RA 10606 - National Health Insurance Act of 2013)

BCS Class III

B

Identify the pharmaceutical dispersed system that is a low-viscosity liquid preparation intended fro application to the skin

A. Lotion

B. Suspension

C. Emulsion

D. Gel

A

(suspension - solid in liquid

emulsion - liquid in liquid

gel - clear, transparent/ jelly-like)

Classify sorbitan monopalmitate as a surfactant

A. Amphoteric

B. Anionic

C. Cationic

D. Non-ionic

D (Amphoteric: betaine

Anionic: soaps, SLS, SLES, LABS

Cationic: benzalkonium Cl

Nonionic: Spans and Tweens)

Choose the method of sealing where a liquid wetting agent is added to lower the melting point of the cap and body then fuses them together at 40-45 degrees Celsius

A. Thermal coupling

B. Heat welding

C. Gelatin banding

D. Fusion method

A (Heat welding - double wall thickness

gelatin banding - band of gelatin)

Identify the S-license issued to the retailers of dangerous drugs and dangerous drug preparations

A. S-1

B. S-3

C. S-5

D. S4

B

Find the correct statement about the HLB values of various surface active agents

A. Deteregents have HLB of 13 to 16

B. Antifoaming agents have HLB values of 1 to 6

C. Water-in-oil emulsifiers have higher HLB values than oil-in-water emulsifiers

D. A surfactant having an HLB value of 10 can be used as emulsifier for w/o emulsions

A

(B: 1-3

C: lower HLB

D: O/W)

Identify the potential observed at the shear plane/tightly bound layer

A. Nernst potential or surface potential

B. Nerns potential or electrokinetic potential

C. Zeta potential or surface potentail

D. Zeta potential or electrokinetic potential

D (Nernst potential or surface potential - electrothermodynamic potential)

Select the components of an erroneous prescription

A. When the brand name and generic name are NOT legible

B. When the generic name is enclosed within parenthesis, and brand name is NOT

C. When the generic name is NOT legible and brand name is legible

D. When only the brand name is written in the prescription

B

(A: impossible prescription

C: violative prescription

D: violative prescription)

Classify PEG ointment as an ointment base

A. Water-removable base

B. Hydrocarbon base

C. Absorption base

D. Water-soluble base

B

(water-removable base - hydrophilic ointment

hydrocarbon base/oleagionus base: yellow/white petrolatum, yellow/white wax, & yellow/white ointment

absorption base: hydrophilic petrolatum, Lanolin USP)

Identify the type of modified release dosage form that has delayed and immediate action

C (Targeted release - isolated in a body organ/tissue

Delayed release - drug release is other than the time of prompt admin

Repeat action/Bimodal Release -> immediate/delayed

Extended release - prompt release followed by gradual release

Select the range of calcium ion concentration in a TPN preparation

A. 5-10 mEq

B. 8-16 mEq

C. 40-60 mEq

D. 100-120 mEq

A (B: Mg

C: PO4

D: Na/Cl)

Find type of powder paper that is transparent, water-proof, and suitable for deliquesent and hygroscopic drugs

A. Bond paper

B. Glassine

C. Vegetable parchment

D. Waxed paper

D

(Bond paper - opaque paper w/ no moisture resistance

Glassine - glazed transparent, moisture-resistant

Vegetable parchment - thin, semi-opaque, moisture-resistant)

Determine the role of corn/potato starch, gums, and alginates in a tablet formation.

A. Flavors

B. Sweetening Agents

C. Disintegrants

D. Lubricants

C

(Disintegrants: starch gum, cellulose - MCC [Avicel], Clays, Ion-exchange resins [poccultin potassium], Cross-linked polymers)

Identify the density that is determined by the displacement of mercury, which does not penetrate at ordinar pressures into pores smaller than 10 micrometers

A. True density

B. Granule density

C. Bulk density

D. Relative density

B (A: material itself -> He

B: material + pores -> Hg

C: material + pores + voids -> grad. cylinder

D: D=Ps/Pa)

Determine the type of cup-and-bob viscometer where the bob is rotated

A. Searle type (bob is rotating