indications et contraindications drugs

Indi benzodiazepines (6)

• insomnia

• anxiety

• alcohol withdrawal

• muscle relaxation

• epilepsy

• general anesthesic

CI benzodiazepines (2)

• BDZ addiction

• sleep apnea

indi barbiturates (2)

• epilepsy → phenobarbital

• general anesthesia → thiopental

indi inhaled anesthetics (2)

• general anesthesia

• severe refractory status asthmaticus

CI inhaled anesthetics (2)

• malignant hyperthermia

• family/personal history malignant hyperthermia

indi IV anesthetics (3)

• induction/maintenance of general anesthesia

• sedation for procedures

• intubation

CI IV anesthetics (2)

• lack of resuscitation knowledge, skill or équipement

• lack of standard monitoring for vital signs

indi conscious sedation (3)

• uncooperative patienta

• anxious patients

• emotionally compromised patients

CI conscious sedation (4)

• COPD

• pregnancy

• prolonged surgery

• psychosis

indications general anesthesia (5)

• mentally challenged patients

• children

• acute dento-alveolar abscess/severe pulpitis

• patients allergic to local anesthetics

• extensive dental procedures

indi ND neuromuscular blockers (4)

• facilitation of endotracheal intubation

• maintenance of muscle relaxation during surgery

• control mechanical ventilation

• reduction of intracranial pressure

CI ND neuromuscular blockers (2)

• conscious patient

• lack of skill or equipment to provide respiratory resuscitation

indi D neuromuscular blockers (2)

• intubation

• need for temporal muscle relaxation

indi adrenegic alpha 1 (3)

• nasal congestion

• hypotension

• eye examination

indi adrenergic alpha 2 (1)

• hypertension

indications bêta 1 (3)

• cardiac arrest

• heart failure

• shock

indications bêta 2 (2)

• asthma

• premature contractions labour

indi alpha 1 blockers (3)

• hypertension

• benign prostatic hyperplasia

• congestive heart failure

indi beta blockers (4)

• hypertension

• acute myocardial infarction

• arrhythmias

• glaucoma

indi direct cholinergic (3)

• urinary retention

• glaucoma

• dry mouth

indi indirect cholinergic (3)

• myasthenia gravis

• azheimer’s

• glaucoma

indi anticholinergic drugs (4)

• bradycardia

• eye examination

• diarrhea/vomiting

• asthma

indi barbiturates (3)

• seizures disorders

• general anestheta

CI barbiturates

• porphyria

indi gaba analogues (2)

• seizures disorders

• neuropathic pain

CI gaba analogues

• hypersensitivity

• fatigue, ataxia

indi phenytoin (3)

• seizure prophylaxis

• partial seizures

• generalized tonic-clonic seizures

CI phenytoin (1)

cardiac conduction disorders

indi carbamazepine (4)

• partial seizures

• trigeminal neuralgia

• generalized tonic clonic seizures

• bipolar disorders

CI carbamazepine (3)

• liver disorders

• myelosupression

• AV heart block

indi valproic acid (5)

• partial seizures

• generalized tonic clonic seizure s

• crisis of absences

• bipolar disorders

• migraine prophylaxis

CI valproic acid (2)

• pregnancy

• severe liver dysfunction

indi TCAs (3)

• major depression

• neuropathic pain

• anxiety disorders

CI TCAs (8)

• confusion

• anxiety

• muscle hypertonicity

• concern

• tremors

• ataxia

• sweating

• hyperthermia

indi SSRIs (4)

• depression

• obsessive compulsive disorders

• generalized anxiety disorder

• bulimia nervosa

CI SSRIs (1)

• concomitant use of SSRIs with MAOIs

indi serotonin and noradrenaline re uptake inhibitors (3)

• generalized anxiety

• social anxiety

• panic disorders

CI serontonin noradrelanine re-uptake inhibitors (1)

ISRN + MAOIs

indi norepinephrine and dopamine reuptake inhibitors (2)

• depression

• smoking cessation

CI norepinephrine and dopamine reuptake inhibitors (4)

• seizures

• dry mouth

• insomnia

• nausea

indi MAOIs (2)

• depression

• MAO-B : Parkinson’s disease

CI MAOIs (2)

• patients on sympathomimétic treatment

• foods rich in tyramine

indi alpha 2 adrenergic antagonist (1)

depression

CI alpha 2 antagonists (1)

concomitant use with MAOIs

indi salicylate (3)

• mild-moderate pain

• fever

• inflammatory disorders

indi aminosalicylates (2)

• ulcerative colitis

• crohn’s disease

CI salycilates (6)

• hypersensitivity

• previous peptic ulcer

• bleeding tendency

• pregnancy

• asthma

• children (reye’s syndrome)

CI aminosalicylates (2)

• hypersensitivity

• children (reye’s syndrome)

indi NSAIDs (3)

• pain

• fever

• inflammation

CI 1st generation NSAIDs (4)

• peptic ulcer

• HT

• renal failure

• blood dyscrasia

CI 2nd generation NSAIDs (2)

• history of CV disorders

• Active Gastric ulcer

indi paracetamol (2)

• moderate to mild pain

• fever

CI paracetamol (2)

• hepatic disorders

• hepatic failure

indi metamizole (2)

• fever

• post operative pain

CI metamizole (4)

• previous agranulocytosis

• disorders of bone marrow/hematopoetic

• acute porphyria

• 3rd trimester pregnancy

indi opioids analgesics (6)

• sedation

• intense pain

• anesthesia

• CNS depression

• anti diarrhea

• antitussive

CI opioids (9)

• brain lesions

• pregnant women

• previous history of drug abuse

• decreased level of consciousness

• Co administration of sedatives

• bronchial asthma

• dense pulmonary secretions

• convulsive disorders

• biliary obstruction

indi typical antipsychotics (6)

• psychosis

• acute agitation

• delirium

• acute mania

• tourette’s syndrome

• intractable hiccups

CI typical antipsychotic (1)

• severe CNS depression

CI antifungal for superficial mycoses (7)

• oral anticoagulants

• oral hypoglycemic a

• phenytoin

• HIV protease inhibitors

• opioids

• immunosuppressants

• ca2+ chanel blockers

CI drugs against herpes virus (1)

• hypersensitivity to the activity substance

indi sulfonamides

• gram +

• gram -

indi sulfamethoxazol (3)

• urinary infections

• respiratory infections

• intestinal infections

indi silver sulfadiazine

• topical use

• burns

indi penicillin G

• gram +

• some gram -

india 2nd generation penicillins/aminopenicillins (5)

• nasopharyngeal infections

• respiratory infections

• urinary infections

• ear infections

• odontogenic infections