Fundamentals of Anatomy & Physiology - Chapter 4: The Tissue Level of Organization

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A comprehensive set of vocabulary flashcards covering the four major tissue types, epithelial specializations, connective tissue components, muscle types, and nervous tissue structure based on Chapter 4 lecture notes.

Last updated 5:54 AM on 6/2/26
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47 Terms

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Tissues

Collections of specialized cells and cell products that perform specific functions.

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Histology

The study of tissues.

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Epithelial tissue

Tissue that covers exposed surfaces, lines internal passageways, and forms glands.

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Connective tissue

Tissue that fills internal spaces, supports other tissues, transports materials, and stores energy.

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Muscle tissue

Tissue specialized for contraction, including skeletal muscle, heart muscle, and muscular walls of hollow organs.

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Nervous tissue

Tissue that carries electrical signals from one part of the body to another.

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Microvilli

Specializations on the apical surface of epithelial cells that increase absorption or secretion.

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Cilia

Hair-like extensions on a ciliated epithelium that move fluids over the surface.

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Cell adhesion molecules (CAMs)

Transmembrane proteins used for intercellular connections to support and communicate.

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Gap junctions

Intercellular connections held together by interlocking transmembrane proteins called connexons that allow rapid communication and passage of small molecules.

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Connexons

Interlocking transmembrane proteins that hold cells together at gap junctions.

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Tight junctions

Connections between two plasma membranes that prevent the passage of water and solutes, keeping enzymes and acids in the lumen of the digestive tract.

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Desmosomes

Intercellular connections where CAMs and proteoglycans link opposing plasma membranes; spot desmosomes tie cells together, while hemidesmosomes attach cells to the basement membrane.

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Basal lamina

The layer of the basement membrane closest to the epithelium.

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Reticular lamina

The deeper portion of the basement membrane that provides strength.

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Mesothelium

The simple squamous epithelium that lines body cavities.

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Endothelium

The simple squamous epithelium that forms the inner lining of the heart and blood vessels.

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Keratin

A protein found in stratified squamous epithelia that adds strength and water resistance.

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Transitional epithelia

Epithelia found in the urinary bladder that can tolerate repeated cycles of stretching without damage.

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Goblet cells

Unicellular exocrine glands in the intestines that secrete mucin, which mixes with water to form mucus.

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Merocrine secretion

A method of secretion where the product is released by secretory vesicles through exocytosis, such as in salivary glands.

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Apocrine secretion

A method of secretion involving the loss of apical cytoplasm and other cytoplasmic components, such as in mammary glands.

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Holocrine secretion

A method of secretion where the cell bursts to release cytoplasmic contents, killing the gland cell, such as in sebaceous glands.

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Matrix

The extracellular components of connective tissue, consisting of extracellular protein fibers and ground substance, which determines specialized function.

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Fibroblasts

The most abundant cell type in connective tissue proper that secretes proteins and hyaluronan (cellular cement).

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Mesenchymal cells

Stem cells in connective tissue that respond to injury or infection by differentiating into fibroblasts, macrophages, or other cells.

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Mast cells

Cells that stimulate inflammation after injury or infection by releasing histamine and heparin.

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Collagen fibers

Long, straight, and unbranched fibers that are the most common in connective tissue proper; they are strong and resist force in one direction.

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Reticular fibers

Interwoven fibers that form a network (stroma) to stabilize functional cells (parenchyma) and resist forces in many directions.

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Elastic fibers

Fibers containing elastin that are branched and wavy, returning to their original length after stretching.

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Mesenchyme

The first embryonic connective tissue to appear in an embryo.

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Wharton's jelly

Another name for mucous connective tissue, a sample of which is taken from the umbilical cord of a fetus.

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Tendons

Dense regular connective tissue structures that attach muscles to bones.

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Ligaments

Dense regular connective tissue structures that connect one bone to another and stabilize organs.

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Aponeuroses

Tendinous sheets that attach a broad, flat muscle to another structure.

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Fasciae

Connective tissue layers and wrappings that support and surround organs.

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Chondroitin sulfates

Polysaccharide derivatives found in the firm gel matrix of cartilage.

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Chondrocytes

Cartilage cells located in chambers called lacunae.

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Antiangiogenesis factor

A substance produced by chondrocytes that discourages the formation of blood vessels, making cartilage avascular.

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Perichondrium

A membrane covering cartilage that contains an outer fibrous layer for support and an inner cellular layer for growth.

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Osteocytes

Bone cells located in lacunae that are arranged around central canals within the matrix.

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Canaliculi

Small channels through the bone matrix that allow for the exchange of materials between osteocytes and the blood.

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Lamina propria

The layer of areolar tissue found in mucous membranes.

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Intercalated discs

Specialized connections that interconnect cardiac muscle cells.

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Neuroglia

Supporting cells of nervous tissue that maintain structure, repair framework, perform phagocytosis, and provide nutrients to neurons.

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Dendrites

Short branches extending from the neuron cell body that receive incoming signals.

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Axon

A long, thin extension of the neuron cell body that carries outgoing electrical signals to their destination.