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Cytology
Study of cells
Gradient
Difference between one area and another area movement of compounds from high to low
Phospholipids
Water loving and has a charge Co2, O2, steroid hormones, lipid soluble drugs
Proteins (Plasma)
Form Ion channels: passive (open), gated (Closed), function as enzymes, link cells together
Cholesterol
Stabilizes Plasma Membrane
Glycocalyx
Glycol proteins & glycolipids (Proteins Lipids with sugar group attached to)
Microvilli
Tiny projections of thew plasma membrane folds and increase surface area
Cell Junctions
3 types of junction
Desmosome
Adjacent cells don’t touch but linked by proteins (skin cells)
Tight Junction
Membrane proteins fuse = impermeable (intestinal cells)
Gap Junction
Channels Between adjacent cells = allows for passage of ions and molecules
Passive Transport
No ATP is used to move compounds across the membrane, compounds move down a gradient movement from high to low
Active Transport
Requires energy = ATP
Simple Diffusion
Molecule pass through phospholipid molecules small and nonpolar solutes do this, depends on gradient
Facilitated Diffusion
Small charged/nonpolar solutes move this wave, requires Ion channels
Omosis
Passive movement of water through semipermeable membrane, occurs when concentration difference between water solutions
Tonicity
Ability of solution to change volume/pressure of cell by osmosis like Isotonic, Hypertonic, Hypotonic
Istonic Solution
Both cytosol and solution have same relative concentration of solutes
Hypotonic Solution
Solution with lower concentration, higher concentration of water than cell, water moves down concentration gradient from outside to inside
Hypertonic Solution
Solution with higher concentration, of solutes than cytosol, water moves down concentration gradient from inside to outside of cell
Solute Pumping
(Active Transport Mechanism) Compounds move against a gradient and carrier molecule (Na+/ K+ pump)
Exocytosis
Compounds exit the cell wrapped in a vesicle that fuses to the Plasma membrane releasing its contents
Endocytosis
Compounds enter the cell in a vesicle, 3 types of
Phagocytosis
Cell eating (Meurophages)
Pinocytosis
Cell drinking (Most cells)
Receptor Mediated Endocytosis (RME)
Cell gets what it needs
Cytoplasm
Located within the plasma membrane around the nucleus
Cytosol
Jello-like substance containing dissolved compounds
Cytoskeleton
Systems of proteins that support organelles, facilitates cel movement maintains cell shape
Microfilaments
(Cytoskeleton Proteins) Cell movement includes muscle contraction (Myosin, Actin)
Intermediate Filaments
(Cytoskeleton Proteins) Helps with strength
Microtubules
Part of of mitotic spindke support movement and cell shape of organelles
Mitochondria
ATP production, aerobic respiration, Kreb’s cycle and electron Transport chain occur here
Ribosomes
Protein Synthesis, made of protein and ribosomal RNA, either attached to rough endoplasmic reticulum or cytoplasm
Rough Endoplasmic Reticulum
Modifies and folds and packages proteins attached to ribosomes, proteins are exported/become part of plasma membrane
Golgi Apparatus
Receives proteins from RER then sorts, modifies, repackages, and exports them, produces digestive enzymes used in Lysosomes
Smooth Endoplasmic Reticulum
Lipid protection and breakdown (Cholesterol and other steroids are produced here)
Lysosomes
Destroy Pathogens & damaged organelles, sac of digestive enzymes, very low O2/Vitamin A weakens Lysosome membrane
Peroxisomes
Use O2 to neutralize toxins & free radical, sacs of oxidase enzymes
Centrioles
Organize mitotic spindle, form cilia and flagella
Proteasomes
Breakdown of protein that damaged, incorrectly folded, or no longer needed, Protein complex
DNA
Deoxyribonucleic acid, polymer composed of nucleotide double helixes
RNA
Ribonucleic acid, single strained, polymer composed of nucleotides, 3 types
mRNA
(Messenger) copy of gene,
tRNA
(Transfer) Transports a specific amino acid to ribosome
rRNA
(Ribosomal) Part of ribosome structure
Transcription
Copying a gene, mRNA is produced themselves the nucleus and travels to ribosomes
Translation
Ribosomes “read” the mRNA and “translate” its sequence of nucleotides into a sequence of amino acids (Protein)