lab 4 diels alder reaction

rules of diels-alder reaction

diene must be in S-cis conformation and stereochemistry of dienophile is retained

endo rule

products form both exo and endo but endo is preferred

reaction

anthracene + maleic anhydride → xylene → diels adduct product

Anthracene

is an irritant, avoid inhalation, ingestion and skin contact

Xylene

is a flammable and an irritant, avoid inhalation, ingestion and skin contact

Maleic anhydride

is toxic and corrosive, avoid inhalation, ingestion and skin contact

solvent is

xylene and boiling stones are added to avoid bumping

most reactive dienes

conjugated dienes locked in a s-cis conformation

dienophiles should have

electron withdrawing groups

dienes should have

electron donating groups

least reactive dienophile

no electron withdrawing groups