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Describe sympatric speciation (6)
mutation occurs randomly which causes variation
members of the same population become reproductively isolated from eachother, without a geographical barrier
preventing gene flow between the two populations
different selection pressures act on the two populations
different allele varieties are favoured in the population, resulting in change in allele frequencies
eventually two populations cannot breed to produce fertile offspring
Describe allopatric speciation (6)
mutation occurs randomly which causes variation
members of the same population become reproductively isolated from eachother by geographical barrier
preventing gene flow between the two populations
different selection pressures act on the two populations
different allele varieties are favoured in the population, resulting in change in allele frequencies
eventually two populations cannot breed to produce fertile offspring
A precaution when marking to make sure estimate is valid, using capture recapture
Marking does not affect survival
How many degrees of freedom to use in Chi squared
phenotypes - 1
Statistical test to see if observed frequencies of phenotypes is different to frequencies expected by Hardy Weinberg
Chi squared
5 Hardy Weinberg Assumptions
no genetic mutations
all genotypes are equally fertile
mating is random
large population
no immigration / emmigration
Hardy Weinberg equillibrium states…
genetic variation in a population iwll remain constant from one generation to the next
Temporal summation
Singular nerve stimulated repeatedly causes enough Na+ to diffuse into axon to reach threshold, causing an action potential
How can the inibition of acetylcholinesterase manage the weakening of muscles (3)
less Ach broken down
Ach can repeatedly rebind to/ stimulate receptors on post-synaptic membrane
Enough Na+ enter to reach threshold
Action potential is produced
3 signs / symptoms that result from a derease in ADH
feeling thirsty
less concentrated urine
frequent urination
What part of the body releases ADH into the blood
Posterior pituitary
Describe the effect of ADH on the collecting duct on the kidneys (3)
Stimulates the addition of channel proteins on membrane
increases premeability to water / more water reabsorbeed
by osmosis
What happens to sacromere when muscle contracts
Decreases in length
Desribe how fast muscle fibres having a higher concentration of glycogen is related to the different properties of these muscle fibres (4)
Fast muscle fibres contract quickly, slow muscle fibres contract slowly
fast fibres mainly use anaerobic respiration, slow muscles use aerobic respiration
fast fibres produce ATP quickly, slow fibres produce ATP slowly
Glycogen is a store of glucose
Describe the myogenic stimulation of the heart and how the regular contraction of the atria and ventricles in coordinated
SAN releases a wave of excitation across atria
causing the atria to contract (atria systole)
after a short delay, the AVN relays the wave of excitation down the
purkyne fibres that form bundles of His
so ventricles contract at the same time from the bottom upwards
Give two reasons why a weightloss programme could be used to treat type 2 diabets but not type 1.
obesirt is a risk factor for type 2 diabetes, not type 1
type 1 diabetes do not produce insulin
describe and explain two precautions required to ensure that the estimate is valid in capture recapture
time delay after release so geckoes spread into population
marking does not effect chances of survival eg is non-toxic. not visible to predators
Describe how to seperate photosynthetic pigments by chromatography (4)
draw line / origin on chromatohraphy paper using pencil and ruler
add chlorophyll solution to origin with tubing / pipette
add solvent below ling / origin
remove stopper before solvent reaches end of chromatography paper
Solvent A seperates 5 pigments. solvent B seperates 6. Explain (2)
two pigments have the same solubility in solvent A
but have different solubiility in solvent B
Ziconotide is a polypeptide that acts on synapses in the spinal cord. why is it injected into the patient’s cerebrospinal fluid? (2)
drug is broken down by enzymes / acid
so drug reaches spinal cord quickly / directly
Z was injected at 3 ng kg-1 h-1 for 8 days into a patient. calculate the total mass in grams of z injected after 8 days into a patient with body mass 82 kg.
1ng = 1×10-9
4.7×10-5 g
In an experiment, why do we sterilise soil? (2)
to remove any pathogens or pest
to ensure no nitrifying / denitrifying bacteria are affecting results
if a gene is sex linked, does sex appear in the phenotype?
Yes
How is orange colour seen when both red-sensitive an green-sensitive photoreceptors are stimulated? (3)
colour vision involves cones
each type of photoreceptor has its own pigment
greater absorbance by red-sensitive cones than green-sensitive cones, therefore more impuulses sent across optic nerve
Why is there a high sensitivity to light in the retina (1)
several photoreceptors connecting to one neurone and spatial summation
V receptors only bind with ADH. Explain why (2)
has specific tertiary structure / 3d shape
structures are complimentary
how does the release of ADH affect blood pressure when blood pressure is decreased
ADH increases reabsorption of water into blood
higher water volume means blood volume increases, increasing blood pressure to normal
Populations of different species form a… (1)
community
how does an increase in glucose and fatty acid transport proteins benefit you when you exercise (4)
more glucose enters muscle cells
glucose / fatty acids enter by facilitated diffusion
fatty acids used in krebs cycle
respiration provides more ATP
how does an incerase in muscle activity increase the heart rate (4)
increased CO2 concentration in blood is detected by chemoreceptors
more impulses are sent to cardiac center by chemoreceptors
more implues are sent along sympathetic pathway / neurones
to SAN
Dengue is a serious disease that is caused by a virus. The virus is carried from one person to another by a mosquito, Aedes aegypti. One method used to try to reduce transmission of this disease is the Sterile Insect Technique (SIT). This involves releasing large numbers of sterile (infertile) male A. aegypti into the habitat. These males have been made infertile by using radiation. 0 2 .
1 Explain how using the SIT could reduce transmission of dengue. [2]
infertile males compete with fetile males for food and resources
decreaing population
The release of radiation-sterilised A. aegypti has not been very successful in controlling the transmission of dengue. Suggest one reason why. [1]
radiation effects courtship behaviours
OR lifespan / survival
name the advantages of aerobic respiration over anaerobic respiration (3)
aerobic respiration happens for longer
aerobic respiration produces more energy
aerobic respiration does not produce lactate / lactic acid
if there are numerical values in the graph you need to…
refer to them in your points
why do you set up a tube of no chloroplasts, but DCPIP, in the light, in the photosynthesis practical (2)
prove that chlorophyll is needed
to prove that DCPIP is not affected by light
The student evaluated the effectiveness of different chemicals as weed-killers by assessing their ability to prevent the decolourisation of DCPIP in chloroplast suspensions.
He added different concentrations of each chemical to illuminated chloroplast suspensions containing DCPIP.
He then determined the IC50 for each chemical. The IC50 is the concentration of chemical which inhibits the decolourisation of DCPIP by 50%.
Explain the advantage of the student using the IC50 in this investigation. (2)
roviudes standard / reference point
Explain why an increase in shoot biomass can be taken as a measurement of net primary productivity.
1. Represents dry mass / mass of carbon;
2. Represents gross production minus respiratory losses;
Give 3 reasons why pancreas transplants are not used for the treatment of type II diabetes.
usually type II produce insulin
receptors less sensitive / responsive to insulin
type 2 treated with diet and exercise
Suggest how transcription factors can reprogramme cells to form iPS cells. [2 marks]
transciption factor binds to promotor region of DNA
stimulating RNA polymerase / transcription
What is meant by the term phenotype? (2)
1. (Expression / appearance / characteristic due to) genetic constitution/genotype/allele(s);
2. (Expression / appearance / characteristic due to) environment;
Any dna in the sample is hydrolysed before mRNA is converted to DNA, before PCR. why? (2)
to remove any DNA present
as this DNA would be amplified
Scientists have used the RT-PCR method to detect the presence of different RNA viruses in patients suffering from respiratory diseases.
The scientists produced a variety of primers for this procedure. Explain why. (2)
base sequence differs
so different complementary primers required
gene pool definition
all alleles in a population
Lord Howe Island in the Tasman Sea possesses two species of palm tree which have arisen via sympatric speciation. The two species diverged from each other after the island was formed 6.5 million years ago. The flowering times of the two species are different.
Using this information, suggest how these two species of palm tree arose by sympatric speciation. (6)
populations in same habitat / area
random mutation produces different flowering times
reproductive isolation, no gene flow
different alleles passed down / change in frequency of alleles
disruptive selection
eventually species cannot interbreed to produce fertile offspring
Yaramul is a town in a historically isolated region of the Andes Mountains. The population of this town has the highest frequency of the E280A mutation in the world.
The origin of the E280A mutation in this population has been traced back to a common ancestor in the 17th century. Natural selection has not reduced the frequency of the E280A mutation in the population. Explain why (2)
small, isolated population so interbreeding
allele inherited from a common ancestor
The age at which the E280A mutation is expressed to cause AD can vary (lines 11–12). Suggest and explain one reason for this. (2)
epigentics / named enviromental factor
methylation
One scientific study which analysed chromosome 14 involved 102 individuals. The scientists recorded a sample size of 204. In this sample they detected 75 E280A mutations but only 74 potential AD cases
WHY (2)
one person had homozygous dominant alleles