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where does thoracic lymph drain on the left?
thoracic duct (at the junction of L internal jugular vein and L subclavian vein)
where does thoracic lymph drain on the right?
right lymphatic duct (R internal jugular vein and R subclavian vein)
Where does lymph drain in the abdomen?
cisterna chyli
Innate or acquired immunity?
Ag independent
innate
Innate or acquired immunity?
Immediate and triggered by microbial structure
innate
Innate or acquired immunity?
phagocytosis by neutrophils and macrophages destroys organisms
innate
Innate or acquired immunity?
complement system can be activated by microbial surfaces (alternative and lectin pathways) and immune complexes (classical pathway)
innate
Innate or acquired immunity?
Ag dependent
acquired
Innate or acquired immunity?
antigenic specificity: able to discriminate subtle molecular differences among molecules
acquired
Innate or acquired immunity?
diversity: ability to recognize and respond to a vast number of different antigens
acquired
Innate or acquired immunity?
ability to remember prior encounter witha. specific Ag
acquired
Innate or acquired immunity?
self and non-self recognition
acquired
Innate or acquired immunity?
cell-mediated immune response by T lymphocytes
acquired
Innate or acquired immunity?
humoral immune response by antibody expression on surface
acquired
primary immune organs
bone marrow and thymus
secondary immune organs
LNs, spleen, MALT
where does myeloma begin?
blood plasma cells
which layer of skin?
outer protective layer, keratinized stratified squamous epithelium derived from embryonic ectoderm
epidermis
which layer of skin?
dense connective tissue layer, gives skin thickness and support, derived from embryonic mesoderm
dermis
which layer of skin?
adipose tissue (superficial fascia)
hypodermis
List some of the epidermal derivatives of the skin?
hair follicles, hair, sebaceous glands, mammary glands, sweat glands, nails
Which layer of epidermis?
dead keratinized cells
stratum corneum
Which layer of epidermis?
limited to the thick skin only, considered a subdivision of the stratum corneum
stratum lucidum
which layer of epidermis?
contains numerous intensely staining granules
stratum granulosum
which layer of epidermis?
spinous layer, light microscopic appearance of short processes extending cell to cell
stratum spinosum
which layer of epidermis?
mitotically active cells, stem cells of epidermis
stratum basale
What kind of epidermal cell?
highly specialized epithelial cells producing keratin
keratinocytes
What kind of epidermal cell?
dendritic cells involved in immune signlaing
langerhans cells
What kind of epidermal cell?
associated with sensory nerve endings
merkel cells
What kind of epidermal cell?
pigment producing cells of the epidermis
melanocytes
how is melanin produced?
oxidation of tyrosine to DOPA by tyrosinase in the stratum basale
In lighter skin, is melanin degraded more rapidly or more slowly than in dark skin?
more rapidly
which layer of dermis?
superficial, consists of loose connective tissue (collagen I and III) that contain blood, lymphatic vessels, and sensory nerve endings
papillary layer
which layer of dermis?
deeper layer, composted of dense irregular tissue containing collagen type I, elastic fibers, and larger blood vessels
reticular layer
what part of the skin has dermal papillae that correspond to epidermal ridges?
epidermal-dermal junction
What do dermal papillae contain in the epidermal-dermal junction?
nerve endings and a network of blood and lymphatic capillaries
How is vitamin D produced in the body?
UV light reacts w 7-dehydrocholesterol in the skin, creating pre-vitamin D which rearranges its structure to form vitamin D
What structures are involved with sebaceous glands, hair matrix, and erector pili muscle?
hair and hair follicles
errector pili
Muscle fiber that is responsible for "hair standing on edge"
mechanism for psoriasis
increased mitotic turnover causing chronic inflammatory disease of the skin
What kind of burn?
involves the epidermis
first degree
What kind of burn?
involves the epidermis and the dermis
2nd degree
What kind of burn?
involves the SC epidermis, dermis, and SC tissue
third degree
what is the most probable cause of cyanosis?
cardiac malformation or congenital heart disease
which cranial nerve function?
smell
olfactory nerve (I)
which cranial nerve function?
vision only
optic nerve (II)
which cranial nerve function?
pupil constriction, accommodation, moves eye up, down, medially, opens eyelids
oculomotor (III)
which cranial nerve function?
supplies superior oblique muscle; moves eye down and inwards
trochlear (IV)
which cranial nerve function?
sensation to face, muscles of mastication
trigeminal (V)
which cranial nerve function?
supplies lateral rectus, moves eye laterally
abducens nerve (VI)
which cranial nerve function?
supplies muscles of facial expression, taste (anterior 2/3 of tongue), closes eyelids, lacrimla, nose, palate glands, submandibular and sublingual salivary glands
facial (VII)
which cranial nerve function?
hearing, regulates balance
vestibulocochlear (VIII)
which cranial nerve function?
sensation and taste to posterior 1/3 of tongue, posterior pharynx, swallowing, and parotid gland salivation
glossopharyngeal (IX)
which cranial nerve function?
parasympathetic supply to eye, heart, gut, lungs, larynx (sensation to airway, motor to vocal cords)
vagus (X)
which cranial nerve function?
supplies SCM (rotates head) and trapezius (lifts shoulders)
accessory nerve (XI)
which cranial nerve function?
supplies tongue muscles motor movement
hypoglossal nerve (XII)
Describe branches of trigeminal nerve?
V1:
V2:
V3:
V1: ophthalmic (sensory) --> gives nasociliary, frontal, and lingual nerves
V2: maxillary (sensory)
V3: mandibular (sensory and motor) --> gives inferior alveolar nerve
Which layer of the scalp?
connective tissue, forms thick, dense, richly vascularized SC layer, well supplied with cutaneous nerves
skin layer (S)
Which layer of the scalp?
wound gaping occurs because this layer is dense
deep connective tissue (C)
Which layer of the scalp?
strong, tendinous sheath that covers calvaria, attachment for frontal and occipital bellies of occipitofrontalis muscle
aponeurosis layer (A)
Which layer of the scalp?
sponge-like layer, danger area of the scalp because pus or blood spread easily in it and infection in this layer can pass to cranial cavity through emissary veins
loose connective tissue (L)
Which layer of the scalp?
dense layer of connective tissue, last layer of scalp
Pericranium (P)
Which extraocular muscle?
abducts, depresses, medially rotates eyeball
superior oblique
Which extraocular muscle?
abducts, elevates, and laterally rotates eyeball
inferior oblique
Which extraocular muscle?
elevates superior eyelied
levator palpebrae superioris
Which extraocular muscle?
elevates, adducts, rotates eyeball medially
superior rectus
Which extraocular muscle?
depresses, adducts, and rotates eyeball laterally
inferior rectus
Which extraocular muscle?
adducts eyeball
medial rectus
Which extraocular muscle?
abducts eyeball
lateral rectus
Which muscle is paralyzed in Horner's syndrome, causing ptosis to develop?
superior tarsal muscle
which part of the eye?
outer white fibrous layer of the eyeball, continuous anteriorly with the transparent cornea
sclera
which part of the eye?
transparent part of outer layer, very sensitive to pain
cornea
which part of the eye?
Vascular middle layer of the eyeball. Continuous anteriorly with the ciliary body, ciliary process, and iris. Provides O2 and nutrients to underlying retina
choroid
which part of the eye?
vascular and muscular extension of choroid anteriorly
ciliary body
which part of the eye?
radiating pigmented ridge on ciliary body; secretes aqueous humor that fills posterior and anterior chambers
ciliary process
which part of the eye?
contractile diaphragm with central aperture (pupil)
iris
which part of the eye gives color
iris
which part of the eye?
transparent, support in capsule by zonular fibers
lens
What is included in the refractive media of eye?
1. Cornea
2. Aqueous humor
3. Lens
4. Vitreous humor
focuses light rays
which part of the eye?
inner layer that is optically receptive part of optic nerve; contains rods (dim light vision) and cones (color vision)
retina
which part of the eye?
yellowish region of retina lateral to optic disc that contains the fovea centralis
macula lutea
which part of the eye?
area of macula with most acute vision; contains only cones
fovea centralis
which part of the eye?
nonreceptive area (blind spot) where retinal ganglion cell nerve axons leave the retina in the optic nerve and pass to the brain
optic disc
lacrimal apparatus
lacrimal glands --> lacrimal ducts --> canaliculi --> sacs --> nasolacrimal ducts
What structure conveys tears from the lacrimal sac to the inferior meatus of nasal cavity?
nasolacrimal ducts
Parts + actions of obicularis oculi muscle?
palpebral: closes eye gently
orbital: closes eye forcefully
lacrimal: drainage of tears
parts + actions of occipitofrontalis muscle?
frontal belly: wrinkles forehead, raises eyebrows
occipital belly: draws the scalp backwards
actions of zygomaticus major
draws the corner of the mouth up and laterally (smile)
actions of obicularis oris
closes and protrudes lips (kissy)
actions of buccinator
presses cheek against teeth, compresses distended cheek (fishy)
where can the facial pulse be palpated?
where the facial artery crosses the inferior border of the mandible immediately anterior to the masseter
facial artery is a branch of which artery?
external carotid artery
facial vein joins with which vein and drains into the internal jugular vein?
retromandibular vein
Which two veins have connections that can lead to ophthalmic infections that can spread into the cavernous sinus? (dangerous)
facial vein and ophthalmic vein
which nerve provides motor innervation to the muscles of facial expression and the platysma?
facial nerve
Where does the main trunk of facial nerve run through?
stylomastoid foramen
which gland is largest of the 3 pair salivary glands?
parotid
Parotid gland
-What kind of salivary gland
-innervated by what nerve
-how does it secrete
-serous gland
-innervated by CN IX (glossopharyngeal)
-secretes via stenson's duct
submandibular gland
-What kind of salivary gland
-innervated by what nerve
-how does it secrete
-seromucous gland
-innervated by CNVII (facial)
-secretes via wharton's duct
sublingual gland
-What kind of salivary gland
-innervated by what nerve
-how does it secrete
-largely mucous gland
-innervated by CNVII (facial)
-secretes via many small ducts in sublingual fold