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SN = Strong Nucleophile; WN = Weak Nucleophile; SB = Strong Base; WB = Weak Base
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SN/WB
methyl = Sn2
1°= Sn2
2° = Sn2
3° = Sn1 depends on sovlent
SN/SB
methyl = Sn2
1° = Sn2 + E2 (polar protic solvent + heat)
2° = Sn2 + E2 (polar protic solvent + heat)
3° = E2
strong, sterically hindered base
methyl = no rxn
1° = E2
2° = E2
3° = E2
WN/WB
methyl = no rxn
1° = no rxn
2° = Sn1 + E1 (if heat applied)
3° = Sn1 + E1 (if heat applied)