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diffusion
the net movement of particles from an area of high concentration to an area of low concentration
plasma
liquid part of blood that carries the blood cells around the body
white blood cell
cell created in bone marrow to destroy microorganisms, produce antibodies and give immunity
red blood cell
(erythrocyte) to transport oxygen via haemoglobin
platelets
cell fragments that release chemicals to make blood clot
heart septum
separates left and right sides of the heart; separates oxygenated and deoxygenated blood, making the heart efficient
pulmonary
to do with lungs
hepatic
to do with liver
renal
to do with kidneys
single circulatory system
blood is pumped from the heart to the gas exchange organ and then directly to the rest of the body
double circulatory system
blood is pumped from the heart to the gas exchange organ, back to the heart and then to the rest of the body
oxygen debt
the volume of oxygen needed to completely oxidise the lactate that builds up during anaerobic respiration
arteries
carry oxygenated blood away from the heart to the organs of the body
veins
carry deoxygenated blood from organs back towards the heart
capillaries
carry blood through organs, bringing the blood close to every cell in the organ
coronary artery
how blood reaches the cardiac muscle and it carries blood to capillaries that supply the heart muscle with oxygen and nutrients
coronary vein
returns blood to the right atrium
phagocytes
perform phagocytosis (ingest microorganisms)
lymphocytes
produce antibodies which stick to surface antigens and destroy the pathogen
primary immune response
the production of antibodies following the first exposure to a foreign antigen
immunity
when the pathogen is quickly dealt with due to memory cells reproducin and producing antibodies
memory cells
lymphocytes that do not immediately get involved in killing microorganisms
fibrinogen
soluble plasma protein
fibrin
insoluble fibres that trap RBCs
secondary immune response
faster and more effective response where the number of antibodies in the blood quickly rises, killing microorganisms before there are enough to cause disease
phagocytosis
phagocytes ingesting microorganisms
pseudopodia
extensions of phagocyte cytoplasm to enclose microorganisms
antigens
chemical markers on the surfaces of pathogens
cardiac muscle
can contract and relax continuously without becoming fatigued; has its own blood supply (coronary blood vessels)
valves
to prevent the backflow of blood
Why don’t unicellular organisms have a transport system?
High SA:V; materials can easily move around the cell
Why do multicellular organisms have a transport system?
Low SA:V; materials cannot reach all parts of the organism
Organs in human circulatory system
heart
blood vessels
blood
What two circulations are in a double circulatory system?
Pulmonary circulation
Systemic circulation
Why do humans have a double circulatory system?
To maintain high blood pressure so blood can pump against gravity and blood can travel quickly to all the organs
Composition of blood
plasma; WBC; RBC; platelets
When does heart rate increase?
Exercise
Adrenaline (stressed/angry/afraid)
When does heart rate decrease?
Sleep
Medulla
part of brain that receives and sends impulses to change heart rate
Veins qualities
blood is under lower pressure than arteries
contain valves
large lumen
thinner walls
Lumen
central cavity in veins/arteries
Capillaries qualities
thin wall to allow for transfer of substances between blood and cell
Arteries qualities
blood is under high pressure
walls can stretch and recoil
small lumen
thick wall
Risk factors of CHD
heredity
high blood pressure
diet
smoking
stress
lack of exercise
Why is the wall of the LV thicker than the right?
blood from the LV is pumped to the rest of the body, so it needs higher pressure; blood from RV is just pumped to lungs
Why are the walls of atria thin?
allows them to stretch as they receive blood; only a small force needed to move blood from atria to ventricles
What do antibodies do when attached to antigens?
cause pathogens to stick together
act as labels
cause pathogens to burst open
neutralise toxins
artificial immunity
becoming immune to a disease without actually contracting the disease
Plasma function
carries dissolved nutrients; hormones; CO2; urea
distributes heat around the body
Adaptations of RBCs
contain haemoglobin
no nucleus
biconcave shape
high SA:V
thin shape
What does clotting do?
prevents further blood loss
prevents entry of microorganisms
Agents in vaccines
weakened strain of microorg
dead microorg
antigen
genetically engineered harmless bacteria