Globular proteins

What are properties?

Compact, water soluble and roughly spherical in shape

What does hydrophobic R-groups do?

On amino acids, are kept away from aqueous environments

Where are the hydrophilic R-groups?

Outside of protein, soluble in water

What are examples of globular proteins?

insulin, haemoglobij and catalyse

What is glucose?

Globular protein based hormone involved in the regulation of blood glucose concentration

Why does insulin need to be soluble?

Transported in the bloodstream

Why do hormone shapes need to be precise?

Need to fit into specific receptors on cell surface membranes

What is haemoglobin made from?

4 alpha helix polypeptide chains

Where are the hydrophobic and hydrophilic R groups?

Phobic- inside, philic- outside, water soluble

What are haem groups and what are they attached by?

The prosthetic groups, they carry oxygen. Attached by covalent bonds

What is catalase?

Enzyme

What is the structure of catalase?

Quaternary protein with 4 prosthetic groips

What do iron ions in the prosthetic groups do?

Allow catalase to interact with hydrogen peroxide and speed up its breakdown

What does haemoglobin contain?

Cysteine (sulfur atoms)