L20 - Receptor Theory

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Last updated 10:01 PM on 4/7/26
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8 Terms

1
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Obj. 1

List an overview of the sequence of events relating to receptor occupation theory (binding and response effect).

2
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Obj. 2

Define the three categories of agonists and the shape of their dose-response curves.

  1. Full agonist

  2. Partial agonist

  3. Inverse agonist

3
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Obj. 3

Define the various ways of antagonism mediated by receptors (competitive vs non-competitive) or without (functional, chemical, pharmacokinetic).

4
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Obj. 4

Compare and contrast the dose-response curves of drugs based on potency and efficacy parameters.

5
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Obj. 5

Define therapeutic index of a drug.

6
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Obj. 6

Define and differentiate between affinity, efficacy, potency of a drug

7
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Obj. 7

Analyze and anticipate changes in a dose-response curve of one drug upon pretreatment with another drug.

8
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Obj. 8

Recognize the mechanisms for drug tolerance by pharmacotherapeutic agents.