Pharmaceutical Analysis 1

These flashcards cover key concepts and terminology from the Pharmaceutical Analysis 1 lecture notes.

Analytical Chemistry

A division of chemistry that provides information relative to the composition of matter, its quantity, and quality.

Assay

The process of determining how much of a given sample is the material indicated by its name.

Qualitative Analysis

Involves the identification, composition determination, and ascertainment of impurities present in a given sample.

Quantitative Analysis

Involves the determination of the quantity or proportion of components in a given sample.

Proximate Analysis

Determination of the total amount of a class/group of active principles in a given sample.

Ultimate Analysis

Determination of a specific component in a sample containing a group of constituents or active principles.

Titrimetric Methods

Analytical methods in which the volume of a solution of known concentration consumed during an analysis is used to determine the amount of an active constituent.

Gravimetric Method

Determination of the mass of the analyte or some compound chemically related to it.

Standardization

Determination of the exact concentration of a solution.

Indicator

A complex, organic substance that shows when the end point of a reaction has been reached, either by a change in color, evolution of a gas, or formation of a precipitate.

Primary Standard Grade

A chemical of such purity that it can be weighed out and used to standardize a solution to a very high degree of accuracy.

Volumetric Flask

Manufactured with capacities ranging from 5 mL to 5L and calibrated to contain a specified volume when filled to a line etched on the neck.

Sources of Error in Volumetric Apparatus

Include issues such as rinse water adhering to walls, grease films, drainage after flow, and variations in temperature.

Buret

Graduated glass tube used for the measurement of variable quantities of liquid, closed at the bottom by a stopcock to control outflow.

Complete Analysis

An analysis where the amount of each constituent of the sample is determined quantitatively.