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What is isovolumetric contraction?
period during ventricular systole when the ventricles contract with no volume change because all heart valves are closed
What is isovolumetric relaxation?
period during ventricular diastole when the ventricles relax with no volume change because all heart valves are closed
What is the end-diastole volume?
filled volume of the ventricle before contraction
What is end-systolic volume?
residual volume of blood remaining in the ventricle after ejection
What is preload?
degree of stretch of the cardiac muscle fibers at the end of diastole
What is afterload?
resistance the ventricles must overcome to eject blood during systole
What is phonocardiography?
recording of heart sounds and murmurs using a sensitive microphone and recording device
What guarantees blood flow through the heart?
pressure gradient
What kind of process is diastole?
passive process but still needs ATP
What phase has semilunar valves closed?
diastole
What phase has AV valves closed?
systole
What are the phases of the cardiac cycle during diastole?
5-2
What are the phases of the cardiac cycle during systole?
3-4
What is phase 5 of the cardiac cycle?
isovolumetric ventricular relaxation
What is phase 1 of the cardiac cycle?
ventricular filling
What is phase 2 of the cardiac cycle?
atrial contraction or atrial systole
What is phase 3 of the cardiac cycle?
isovolumetric ventricular contraction
What is phase 4 of the cardiac cyle?
ventricular ejection or systole
What phase is S2 associated with?
phase 5; associated with closure of the semilunar valves
What phase is S3 associated with?
ventricular filling
What phase is S4 associated with?
atrial contraction
What animal is it normal to hear the S3 and S4?
horses
What phase is associated with S1?
phase 3; associated with the AV valves closing
When does the pulse occur?
just after S1
What is the pressure-volume loop?
graph of left ventricular pressure against left ventricular volume to explore the intricacies of the heart's function
What is another term for left ventricular end-diastolic pressure (LVEDP)?
preload
What is another term for systemic vascular resistance (SVR)?
afterload
When is preload increased?
during hypervolemia and regurgitation of cardiac values
When is afterload increased?
during hypertension and vasoconstriction
What is the Frank-Starling Mechanism?
preload leads to stronger contraction and greater stroke volumes; ventricular filling is increased which stretches the fibers and troponin C becomes more sensitive to Ca leading to more force
What happens to cardiac output with increased preload?
increases cardiac output
3 multiple choice options
What happens to cardiac output with increased contractility?
increases cardiac output
3 multiple choice options
What causes decreased cardiac ouput?
increased afterload
3 multiple choice options
What generates heart sounds?
generated by the oscillation of blood and vibrations of muscles and valves
What are heart murmurs?
abnormal heart noises; generally S1 or S2
What causes heart murmurs?
altered valves, abnormal openings, anemia
Where do you listen for the mitral valve?
left side 5th intercostal space; S1 louder
Where do you listen for the aortic valve?
left 4th intercostal space dorsal to MV; S2 heard better
What valve can be heard from the left 3rd intercostal space at the sternal border?
pulmonic valve
What valve can be heart from the right 3rd and 4th intercostal space?
tricuspid valve
What are heart murmurs graded out of?
6
How are heart murmurs graded?
by their intensity
What is a 1/6 heart murmur?
nearly imperceptible; need careful auscultation with quiet environment; always focal
What is a 2/6 heart murmur?
heard readily but soft; always focal
What is a 3/6 heart murmur?
heard readily, moderate intensity; usually regional
What is a 4/6 heart murmur?
heard readily, loud, and usually radiates widely but without a palpable thrill
What is a 5/6 heart murmur?
heard readily, loud, and associated with a precordial thrill, but the murmur is not heard with the stethoscope lifted off the surface of the thorax
What is a 6/6 heart murmur?
heard readily, loud, associated with a precordial thrill, murmur remains audible with the stethoscope lifted 1 cm off the surface of the thorax
What is stenosis?
acquired or congenitally undersized valve or blood vessel; hear the murmur when the valve opens
What is insufficiency?
leakage of a valve during its closure; hear the murmur when the valves close
What valves will produce a stenosis murmur during systole?
semilunar valves
What valves will produce an insufficiency murmur during systole?
atrioventricular valves
What kind of murmur is it when it is heard while the atrioventricular valves are opening?
diastole stenosis
What kind of murmur is it when it is heard while the semilunar valves are closing?
diastole insufficiency
What part of the ECG occurs during a mitral valve insufficiency murmur?
begins during the QRS complex and ends during the T wave
What are the shunts in circulation during fetal development?
ductus arteriosus and foramen ovale
What causes blood to flow through the ductus arteriosus?
high pressure in collapsed lungs and low pressure in placenta causes a gradient for the blood to flow from pulmonary trunk to aorta
What is one of the most common congenital heart defects identified in dogs?
patent ductus arteriosus
How does the ductus arteriosus normally close?
at birth lung expansion occurs and there is higher oxygen tension which it is sensitive to; it contracts and the smooth muscle undergoes degeneration
What kind of murmur does the patent ductus arteriosus cause?
machinery/continuous murmurs during systolic and diastolic; has a combination of stenosis and insufficiency