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Thalamus
relay to the cortex and its nuclei
Hypothalamus
the infundibulum, the mammillary bodies, functional homeostasis
Epithalamus
pineal gland, and habenula
Thalamus functions
Neural mediation to/from the cortex (sensory, motor, also limbic)
Hypothalamus functions
Regulates homeostasis (functional connections with autonomic, limbic system)
• Direct relay with pituitary= through infundibulum
• Indirect relay with pituitary= through hormones into Hypothalamohypophyseal portal venous system (HHPV)
Pituitary functions
• Hormone secretion for growth, metabolism, reproductive, and other endocrine functions
• Melatonin (sleep and circadian rhythm)
Thalamus Structural features
2 ovoid-shaped structures, joined by a midline bridge = massa intermedia
The spinal sensory tracts terminate in the ____, then ____ order neurons to the cortex via the ___
thalamus, 3 rd or 4th, internal capsule
Descending motor tracts (____) pass ____ through the internal capsule
corticospinal, corticobulbar, corticopontine; lateral to thalamus
Thalamus is located between the_____to the brainstem
hemispheres, adjacent to 3rd ventricle and superior
“diencephalon” Latin =
in the midst/between the brains
Thalamus nuclei is divided by
Subdivided into dorsal or ventral portions, AND anterior or posterior
Anterior nuclei=
relays within the limbic system, (emotions, memory, and learning)
The medial nuclei=
sensory and emotional integration
Lateral thalamus nucleus has many specific nuclei for
sensory, motor, and integrative information.
Thalamic Pain Syndrome
More frequently leads to the sensation of excruciating pain
VPM and VPL (ventral posterior medial and lateral nuclei) thalamus nuclei
hypo esthesisas from the head and body on the contralateral side.
Hypothalamus Nuclei distributed by “quadrants” in this orientation:
Medial-lateral and Rostro-caudal
Rostral nuclei =
by proximity to optic chiasm
Pre-optic=
reproductive function (engage with hormone release from anterior pituitary, sexually dimorphic)
Supra chiasmatic=
regulate circadian rhythms
Anterior hypothalamic =
heat dissipation
Paraventricular and supraoptic (water conservation) =
production of these hormones=oxytocin and anti-diuretic hormone ADH)
Caudal nuclei =
regulate sympathetic function and heat conservation
Tuberal region with 3 nuclei:
dorsomedial, ventromedial, lateral (food intake by satiety/hunger)
Tuberal region Lateral =
regulates hunger
Tuberal region Medial=
regulates satiety
Fornix (white matter tract) connects to
hippocampus (limbic system)
Arcuate=
energy/metabolism, endocrine functions, (input from insulin for glucose uptake or from leptin for fat utilization)