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benazepril
avoid pregnancy, side effect: dry cough, may cause dizziness, use K supplements under medical supervision, seek medical attention with any facial swelling
enalapril
avoid pregnancy, side effect: dry cough, may cause dizziness, use K supplements under medical supervision, seek medical attention with any facial swelling
lisinopril
avoid pregnancy, side effect: dry cough, may cause dizziness, use K supplements under medical supervision, seek medical attention with any facial swelling
clonidine
avoid alcohol and CNS depressants, caution with driving, swallow ER tablet whole, apply patch to hairless area and rotate locations, avoid abrupt discontinuation
carvedilol
avoid abrupt discontinuation, diabetic patients should monitor blood sugar levels
valsartan
avoid pregnancy and sudden discontinuation, use K supplements under medical supervision
losartan
avoid pregnancy and sudden discontinuation, use K supplements under medical supervision
atenolol
avoid abrupt discontinuation, diabetic patients should monitor blood sugar levels
metoprolol
avoid abrupt discontinuation, diabetic patients should monitor blood sugar levels
propranolol
avoid abrupt discontinuation, diabetic patients should monitor blood sugar levels
amlodipine
report signs of peripheral edema, fatigue, hypotension, or hepatic dysfunction
diltiazem
follow administration instructions specific to prescribed brand, some products can be opened and sprinkled on applesauce
nifedipine
take on an empty stomach, avoid sudden discontinuation and grapefruit juice, may see tablet/shell of doasge form in stool
verapamil
do not crush/chew ER products, contents of ER capsules may be sprinkled on food, avoid sudden discontinuation, rise slowly from sitting/lying position to avoid dizziness, avoid alcohol and grapefruit juice
potassium chloride (oral)
take w food, take powder/granule/oral liquid after mixing in 4 oz of water, capsules may be sprinkled on food, completely dissolve effervescent tablets in liquid
furosemide
avoid alcohol and NSAIDs, increased risk of sun-sensitivity
hydralalzine
avoid abrupt discontinuation, report chest pain
triamterene with hydrochlorothiazide
may cause dizziness, avoid foods that are high in K, avoid NSAIDs, may cause photosensitivity, caution in patients with sulfonamide allergy
spironolactone
may cause dizziness, report signs of hyperkalemia and hyponatremia, avoid K supplements and NSAIDs
chlorothalidone
take in am w food, avoid alcohol and NSAIDs, may cause dizziness
hydrochlorothiazide
take early in the day to avoid nocturia, report signs of hypotension and dizziness, avoid NSAIDs
amiodarone
use sunscreen, report signs of cardiac arrhythmias, has multiple drug interactions, take consistently w regard to meals but avoid taking w grapefruit juice
colchicine
instruct patient on appropriate dosing strategy for gout flares
rivaroxaban
educate patient on signs of bleed and interactions w other anticoagulant medications, warn of risks of epidural anesthesia, doses greater than 15 mg should be taken w food, take w evening meals for nonvalvular atrial fibrillation
warfarin
report signs of hemorrhage, avoid situations where injury is likely to occur, has many drug interactions, avoid alcohol, cranberry, and changes in vitamin K consumption
digoxin
take after am meals, report signs of bradycardia, avoid abrupt discontinuation
apixaban
educate patient on signs of bleeding, take w or w/o food, should be interrupted before dental/surgical procedures, avoid NSAIDs and aspirin
isosorbide mononitrate
take on empty stomach, swallow ER tablet whole, can cause headaches and dizziness, avoid driving and operating machinery, stand up slowly, avoid abrupt discontinuation, avoid concurrent use of PDEEs, IR dose should be taken at least 7 hrs apart
nitroglycerin (sublingual and injectable)
sit prior to administration, tablet should be dissolved under tongue, do not eat or drink after placement of tablets, rise slowly, avoid use of alcohol and CNS depressants, ointment may stain clothing
sacubatril/valsartan
avoid abrupt discontinuation, use K supplements under medical supervision, may cause dizziness, avoid driving and operating machinery, avoid NSAIDs
clopidogrel
report signs of bleeding, avoid abrupt discontinuation
cyanocobalamin (vitamin B12)
may require several weeks for effect, take ER products w food, avoid alcohol
fenofibrate
report signs of rhabdomyolysis, do not use if you have severe kidney or liver disease
gemfibrozil
take 30 min before breakfast and dinner, report signs of rhabdomyolysis, do not use if you have severe kidney or liver disease
ezetimibe
take w or w/o food, may be taken at the same time as a concurrent statin
atorvastatin
avoid alcohol and grapefruit juice, notify prescriber if muscle tenderness or weakness occurs
pravastatin
take in evening, avoid alcohol and grapefruit juice, notify prescriber if muscle tenderness or weakness occurs
rosuvastatin
avoid alcohol, notify prescriber if muscle tenderness or weakness occurs
simvastatin
avoid alcohol, notify prescriber if muscle tenderness or weakness occurs
buspirone
avoid activities requiring mental alertness, avoid abrupt discontinuation, avoid alcohol and grapefruit juice
alprazolam
may cause drowsiness, avoid alcohol, do not crush, do not self-increase or discontinue abruptly
clonazepam
may cause drowsiness, avoid alcohol, allow disintegrating tablet to dissolve under tongue
diazepam
may cause drowsiness, avoid alcohol
lorazepam
may cause drowsiness, avoid alcohol
temazepam
may cause drowsiness, avoid alcohol, take 30 min prior to bed
zolpidem
take on empty stomach, may cause drowsiness, avoid alcohol, take before bed, avoid alcohol and CNS depressants, monitor respiration at night
vareniciline
take after meal w glass of water, may be used w other nicotine replacement products, limit alcohol use
desvenlafaxine
take w or w/o food, avoid alcohol, avoid abrupt discontinuation, avoid activities requiring mental alertness
duloxetine
report withdrawal symptoms and worsening depression, avoid alcohol, taper dose slowly
venlafaxine
take w food, avoid alcohol, swallow ER capsules/tablets whole, avoid abrupt discontinuation, avoid activities requiring mental alertness, may cause dizziness
citalopram
avoid activities requiring mental alertness, report worsening depression, avoid abrupt discontinuation, avoid alcohol, NSAIDs, and aspirin
escitalopram
avoid activities requiring mental alertness, report worsening depression, avoid alcohol, NSAIDs, and aspirin
fluoxetine
take w/o meals in the morning, avoid activities requiring mental alertness, report worsening depression, avoid alcohol, NSAIDs, and aspirin
paroxetine
do not chew/crush, avoid activities requiring mental alertness, avoid abrupt discontinuation and alcohol, caution with NSAIDs and aspirin
sertraline
avoid activities requiring mental alertness, avoid abrupt discontinuation, alcohol, NSAIDs, and aspirin
amitriptyline
avoid activities requiring mental alertness, avoid abrupt discontinuation, report worsening depression
buproprion
avoid alcohol, CNS depressants, and activities requiring mental alertness, take at the same time each day, ER tablet shell may be visible in stool
trazadone
avoid driving and other activities requiring mental alertness, avoid abrupt discontinuation, avoid alcohol, barbiturates, and CNS depressants
mirtazapine
open pack with dry hands, avoid activities requiring mental alertness, report worsening depression, avoid alcohol, take in pm
prazosin
avoid activities requiring mental alertness, rise slowly, avoid abrupt discontinuation and alcohol
lithium
swallow ER tablets whole, avoid activities requiring mental alertness, report signs of toxicity, maintain adequate fluid intake
lisdexamfetamine
take in am w or w/o food, monitor growth in children, report psychiatric problems and chest pain
dextroamphetamine
avoid taking in afternoon or evening, avoid GI alkalizing agents and alcohol, report chest pain or seizures
methylphenidate
avoid taking in pm, swallow ER capsule whole, avoid abrupt discontinuation, apply patch at same time each day alternating hips
carbamazepine
may decrease effectiveness of oral contraceptives, avoid activities requiring mental alertness, take w food, avoid alcohol, grapefruit juice, and abrupt discontinuation
divalproex (includes valproate or valproic acid VPA)
avoid activities requiring mental alertness, take w food, avoid alcohol and abrupt discontinuation
gabapentin
first dose should be taken at pm, ER dose should be taken w pm meal, avoid activities requiring mental alertness, report worsening depression, avoid abrupt discontinuation, wait 2 hrs after antacid before taking
lamotrigine
seek medical attention if rash occurs, slow titration necessary, avoid alcohol, place disintegrating tablet on tongue and allow to dissolve
levetiracetam
swallow ER tablet whole, avoid activities requiring mental alertness, report mood swings, avoid abrupt discontinuation
phenytoin
shake suspension before administration, don't crush ER capsules, avoid activities requiring mental alertness, avoid alcohol, has many drug interactions
pregabalin
solution must be used w/i 45 days of opening, avoid activities requiring mental alertness and abrupt discontinuation
topiramate
avoid activities requiring mental alertness and abrupt discontinuation, maintain adequate fluid intake, decreases effectiveness of oral contraceptives, take a missed dose ASAP
carbidopa with levodopa
place disintegrating tablet on top of tongue
donepezil
take at pm w or w/o food, allow disintegrating tablet to dissolve on tongue, report signs of GI bleeding
ropinirole
take w food, avoid activities requiring mental alertness, abrupt discontinuation, alcohol, and CNS depressants
pramipexole
take w food, avoid activities requiring mental alertness, abrupt discontinuation, alcohol, and CNS depressants
memantine
may be taken w or w/o food, use packaged device for administration
atomoxetine
avoid activities requiring mental alertness, monitor growth in children, do not open capsules
aripiprazole
avoid activities requiring mental alertness, may impair heat regulation, report worsening depression and increased seizure activity, avoid abrupt discontinuation and alcohol
lurasidone
take w food, avoid activities requiring mental alertness, report worsening depression, avoid abrupt discontinuation and alcohol
olanzapine
avoid activities requiring mental alertness, may impair heat regulation, rise slowly, report symptoms of tardive dyskinesia, diabetic patients should monitor for hyperglycemia, avoid alcohol
quetiapine
take w food, avoid alcohol, avoid activities requiring mental alertness, rise slowly
clozapine
avoid alcohol, call healthcare if dose is missed, avoid abrupt discontinuation, report signs of infection, educate patients on drug-induced constipation
risperidone
take w food, avoid alcohol and CNS stimulants, avoid activities requiring mental alertness, keep tablet in blister pack until use, oral solution may be mixed w water but shouldn't be mixed w cola or tea