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Examples of Anesthetics:
Benzocaine, Lidocaine, and Pramoxine
Anesthetic Frequency
Apply sparingly to up to 3-4x/day
Formulations of Anesthetics
Benzocaine:
Lidocaine HCl:
Pramoxine HCl:
Gel, cream, ointment, and spray
Gel, cream, ointment, and spray
Gel, cream, lotion, spray, liquid
Examples of Topical Antiseptics
Hydrogen Peroxide, Ethyl Alcohol, Isopropyl Alcohol, Iodine/Sodium Iodine, Povidone/Iodine, and Camphorated Phenol
ADEs of Topical Antiseptics
Hydrogen Peroxide:
Ethyl Alcohol:
Isopropyl Alcohol:
Iodine/Sodium Iodine:
Povidone/Iodine:
Camphorated Phenol:
Tissue toxicity
Drying of skin and tissue irritation
More drying of skin than ethyl alcohol and cytotoxic/irritating
Skin irritation, allergic sensitization, and may stain skin
Non-irritating (applied to wound beds), short-term thyroid dysfunction or dysplasia with increased absorption
Cytotoxic
Hydrogen Peroxide: do noy apply when _________, _________ may be preferred
Ethyl Alcohol: _________
Isopropyl Alcohol: more _________
Iodine/Sodium Iodine: Do NOT use _________
Povidone/Iodine: _________ and systemic absorption with increasing amount
Camphorated Phenol: _________
gas cannot escape, soap and water
flammable
bactericidal activity and flammable
Lugol’s Solution and avoid dressing
rapid bactericidal activity
oily and avoid dressing
Frequency of Antispetics:
Apply sparingly 1-3x/day PRN to intact skin
Examples of Antibiotics:
Neomycin, Bacitracin Zinc, and Polymyxin B
Dosing and Brand Name of
Neomycin
Dosing:
Brand Names:
Bacitracin Zinc:
Dosing:
Brand Names:
Polymyxin B:
Dosing:
Brand Names:
3.5 mg/g
Neosporin Ointment, Neosporin + Pain Relief Ointment, and Gold Bond First Aid Antibiotic Ointment
400 U/g (Neosporin and Gold Bond) and 500U/g (Polysporin and Betadine)
Same as Neomycin and additionally Polysporin Ointment/Powder and Betadine First Aid Antibiotics + Moisturizer Ointment
5,000 U/g (Neosporin and Gold Bond) and 10,000 (Polysporin and Betadine)
Polysporin Ointment/Powder and Betadine First Aid Antibiotics + Moisturizer Ointment Ingredients:
Polymyxin B, Bacitracin Zinc, Neomycin, and Pramoxine HCl (10mg/g)
Topical Antibiotic Frequency:
apply sparingly 1-3x/day

KNOW IMAGE
Which fungal infections can Butenafine, Terbinafine, Tolnaftate, and Clotrimazole/Miconazole be used to treat?
Tinea pedis, cruris, and corporis
Dosing and Frequency of Butenafine:
Tinea Pedis:
Tinea Cruris:
Tinea Corporis:
BID x 1 week (not that effective) or QD x 4 weeks (more effective)
QD x 2 weeks
QD x 2 weeks
Dosing and Frequency of Terbinafine:
Tinea Pedis:
Tinea Cruris:
Tinea Corporis:
BID for 1-2 weeks, Between toes x 1 week and Bottom/Sides x 2 weeks
QD x 1 week
QD x 1 week
Dosing and Frequency of Tolnaftate:
Tinea Pedis:
Tinea Cruris:
Tinea Corporis:
BID x 4-6 weeks
BID x 2 weeks
BID x 4-6 weeks
__________ can be used QD for PPX after infection (the only OTC) and has delayed hypersensitivity
Tolnaftate
Dosing and Frequency of Clotrimazole/Miconazole:
Tinea Pedis:
Tinea Cruris:
Tinea Corporis:
BID x 4 weeks
BID x 2 weeks
BID x 4 weeks
How long should you use Salts of Aluminum?
1 week
Which fungal infection medications can be used in pregnant women? Which one is FDA approved?
Clotrimazole (FDA approved)/Miconazole
How long can these medications be used for?
Clotrimazole:
Miconazole:
Tioconazole:
3 days or 7 days
1 day, 3 days, or 7 days
1 day
What are the brand name(s)?
Clotrimazole:
Miconazole:
Tioconazole:
Gyne-Lotrimin
Monistat
Vagistat or Monistat
Clotrimazole (Dosage Form/Frequency):
3-Day:
7-Day
Cream BID PRN
Cream BID PRN or Tablet (combo)
Miconazole (Dosage Form/Frequency):
1-Day:
3-Day:
7-Day:
Cream BID PRN or Suppository (1200 mg)
Cream BID PRN
Cream BID PRN or Suppository (100 mg)
Tioconazole (Dosage Form/Frequency):
1-Day:
Ointment (6.5%)
All creams for VVC treatments are 2%, EXCEPT:
7-Day Gyne-Lotrimin (1%) and 3-Day Monistat
DDI with warfarin → increased risk of _______ (increases _______)
bleeding, warfarin
Other VVC treatments
Benzocaine/resorcinol → _______
Boric acid capsules/ointment → ____Candida albicans + Compounded
Gentian violet → _______ Candida organisms + _______
Hydrocortisone 1% → _______
Povidone/iodine 0.3% → _______
Cornstarch, aloe, mineral oil → May be helpful for _______
Yogurt
Analgesia and Pruritis
Non-
Resistant and will stain
Anti-inflammatory and Pruritis
Antiseptic
Discharge and Pruritis
Least sedating Medications for Allergies:
INCS such as Fluticasone (Flonase/Flonase Sensimist), Budesonide (Rhinocort), Triamcinolone (Nasacort Allergy 24HR), and Mometasone (Nasonex)
Moderately sedating Medications for Allergies:
Loratidine (Claritin), Fexofenadine (Allegra), Levocetirizine (Xyzal), and Cetirizine (Zyrtec)
Juices and citrus products will decrease the efficacy of ______ allergy medication.
Fexofenadine (Allegra)
Most sedating Medications for Allergies:
Diphenhydramine (Benadryl), Doxylamine (Unisom), Chlorpheniramine (Chlor-Trimeton), and Brompheniramine (Dimetapp)
Fluticasone Furoate/FF (Flonase Sensimist) Dosage:
12 y/o and older: 2 sprays in each nostril BID (1st week) and 1-2 sprays in each nostril QD (Week 2+)
2-11 y/o: 1 spray in each nostril QD
Fluticasone Propionate/FP (Flonase/Allergy Relief) Dosage:
12 y/o and older: 2 sprays in each nostril BID (1st week) and 1-2 sprays in each nostril QD (Week 2+)
4-11 y/o: 1 spray in each nostril QD
Budesonide (Rhinocort) Dosage:
12 y/o and older: 2 sprays in each nostril QD
6-11 y/o: 1 spray in each nostril QD
Triamcinolone (Nasacort Allergy 24HR) Dosage:
12 y/o and older: 2 sprays in each nostril QD
2-11 y/o: 1 spray in each nostril QD
Mometasone (Nasonex) Dosage:
12 y/o and older: 1-2 sprays in each nostril QD
Doxylamine (Unisom) Dosing/Frequency:
12 y/o and older: 7.5-12.5 mg q4-6h
6-12 y/o: 3.75-6.25 mg q4-6h
Diphenhydramine (Benadryl) Dosing/Frequency:
12 y/o and older: 25-50 mg q4-6h
6-12 y/o: 12.5-25 mg q4-6h
Fexofenadine (Allegra) Dosing/Frequency:
12 y/o and older: 60 mg BID OR 190 mg QD
2-12 y/o: 30 mg BID
Take ______ with water and avoid concurrent aluminum and magnesium products
Fexofenadine (Allegra)
Loratidine (Claritin) Dosing/Frequency:
6 y/o and older: 10 mg QD
2-6 y/o: 5 mg QD
Brompheniramine (Dimetapp) and Chlorpheniramine Maleate (Chlor-Trimeton) Dosing/Frequency:
12 y/o and older: 4 mg q4-6h
6-12 y/o: 2 mg q4-6h
2-6 y/o: 1 mg q4-6h
Cetirizine (Zyrtec) Dosing/Frequency:
12 y/o and older: 10 mg QD
6-12 y/o: 5-10 mg QD
2-6 y/o: 2.5-5.0 mg QD
Levocetirizine (Xyzal) Dosing/Frequency:
12 y/o and older: 5 mg QD
6-12 y/o: 2.5 mg QD
6 mo.-6 y/o: 1.25 mg QD
Contraindication for ________: end stage renal disease, hemodialysis, children with renal impairment
Levocetirizine (Xyzal)
INCS → _______
2nd Gen AH → _______
1st Gen AH → _______
Intranasal decongestants → _______ (varies), BUT → only _______ max
Cromolyn → _______ (annoying → low adherence)
QD
QD
q4-6h
BID
3-5 days
3-6x/day
Ketotifen Fumarate (OTC) Dosing/Frequency
1 drop in each affected eye BID
Pheniramine + Naphazoline (Combo) Dosing/Frequency
1-2 drops into affected eyes QID (4x)
Olopatadine (Prescription / OTC depending on formulation) Dosing/Frequency
0.2% and 0.7%: One drop in each eye QD
0.1%: One drop in each eye BID dosing
Ketotifen Fumarate (OTC) Used for:
Mild-to-Moderate Allergic Conjunctivitis for 3 y/o or older
Pheniramine + Naphazoline (Combo) Used for:
Allergic Conjunctivitis for 3 y/o or older
Olopatadine (Prescription / OTC depending on formulation) Used for:
Allergic Conjunctivitis for 2 y/o or older
Ketotifen Fumarate (OTC) SEs:
headache, blurred vision, change in taste, and eye irritation
Pheniramine + Naphazoline (Combo) SEs:
blurred vision and eye irritation
Olopatadine (Prescription / OTC depending on formulation) SEs:
headache, blurred vision, change in taste, and eye irritation
Mild intermittent or episodic —> 1st line treatment is:
AH or AH + Decongestant