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increase, excessive
the bottom line of HD is that there is decreased inhibition of the thalamus causing a/n (decr/incr) activation of the cortex and ________ motor ability
genetically inherited
HD is generally ________________ and rarely spontaneous
T
T/F: HD is neurodegenerative
CAG, earlier
HD is based on genetic _____ repeats, and the more repeats there are, the ______ the onset
40
____ or more CAG repeats is considered HD
family history
genetic testing
neuroimaging
presence of motor disability, chorea, cognitive decline
diagnosis process for HD:
15-20
the prognosis for HD is death within ___-___ years of onset of symptoms
suicide
there is a high risk of _______ for people with HD
UHDRS unified HD rating scale
the _________ is an outcome measure for HD with lots of adls, and a higher score means less disability
chorea, voluntary
the primary motor impairment of HD is _______, and overall difficulty with _______ movement
slowed thought processes
difficulty learning new information
primary cognitive impairments with HD are ___________ and ______________
duh
HD has a lot of psychosocial and overall life impacts