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Energy Balance, Obesity, and Weight Management
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energy balance
the balance between energy intake (diet) and energy output (expenditure)
when intake = output → weight management
when intake > output → weight gain
when intake < output → weight loss
energy intake
calories consumed from foods and beverages, including carbohydrates, protein, fats, alcohol
energy expenditure
the amount of energy (calories) the body uses
what are the 3 main components of energy expenditure?
Basal Metabolic Rate, Thermic Effect of Food, and Physical Activity
Basal Metabolic Rate (BMR)
the minimal amount of energy the body uses to stay alive, including maintaining body temperature, breathing, and pumping blood; varies based on age, sex, and body composition
makes up 60% to 80% of total energy expenditure
what factors impact a person’s BMR?
more muscle, growth, stress/illness → increase BMR
aging, starvation, low thyroid hormones → decrease BMR
Thermic Effect of Food (TEF)
the energy cost of digesting, absorbing, and processing food
makes up 8% to 16% of total energy expenditure
Physical Activity
any bodily movement produced by skeletal muscles that results in energy expenditure; varies considerably between individuals and across time
makes up 15% to 30% of total energy expenditure
Body Mass Index (BMI)
measure used to estimate whether a person is underweight, normal weight, overweight, or obese; risk increases
weight (kg) ÷ height (m2)
What are the BMI categories?
Underweight → < 18.5 BMI
Healthy → 18.5 – 25.9 BMI
Overweight → 25.0 – 29.9 BMI
Obese → ≥ 30.0 BMI
what BMI range is linked to lowest risk of death?
between 20 and 25
risk increases when BMI rises and declines
what has been the trend in the prevalence of obesity in the US in recent years?
prevalence of obesity has increased over time
about ¾ of US adults are overweight or obese
about 1/3 of US children are overweight or obese
what are limitations of using BMI to assess health status?
doesn’t take into account muscle mass vs. body fat
doesn’t take into account location of body fat
varies naturally by age (muscle declines with age)
doesn’t account for variations in body fat with sex, race, and ethnicity
different races and ethnicities have have different cutoffs for health risks
what is an alternative method we can use to assess health risks associated with weight or body composition?
Percent Body Fat → considers variation in cutoffs from different sources
percent body fat
proportion of a person’s total body weight that is made up of fat tissue, used to asses health and disease risk
what are the body fat % ranges (based on percent body fat)?
Men → 18% to 25% is average, above 25% is unhealthy
women → 25% to 31% is average, above 32% is unhealthy
what are the health risks of obesity?
higher risk for chronic diseases (type 2 diabetes, CVD, high blood pressure, stroke, cancers), liver disease, infertility, and reduced overall health
what are the social and psychological consequences of obesity?
stereotyped as lazy and lacking self control
stigma and bias → judged on appearance, not character
feelings of rejection, shame, and depression
ineffective treatments can lead to a sense of failure
what are the health risks of being underweight?
decreased immune function, infertility, higher risk of CVD and stroke
visceral fat
fat stored deep in the abdomen around internal organs (liver, pancreas, intestines); high health risk, especially for CVD
increases risk of metabolic syndrome → higher inflammation, insulin resistance
subcutaneous fat
fat stored directly under the skin; most visible type of body fat and is less harmful than visceral fat
central (android) obesity
body fat is stored primarily in the upper body and abdomen, leading to an apple-shaped figure; associated with higher risk of obesity-related diseases
gynoid obesity
body fat stored primarily in the lower body, leading to a pear-shaped figure
what are some physiological (inside-the-body) theories about the cause of obesity?
genetics, epigenetics, and obesity → genes and gene-environment impact our ability to gain or lose weight
gut microbiome and dysbiosis → imbalance of gut bacteria may affect energy balance and promote weight gain
thermogenesis and BAT → differences in energy expenditure through heat production (brown adipose tissue) may influence weight gain
epigenetics
how environment and behaviors affect gene function
can influence tendency to gain weight or stay lean, though our genes haven’t changed
dysbiosis
maintenance of normal gut bacteria
imbalance may lead to obesity risk
what is the difference in white adipose tissue and brown adipose tissue?
white → energy storage
brown → energy storage and maintenance of body temperature
heat generating tissue, which may protect against obesity
what are some environmental (outside-the-body) theories about the cause of obesity?
external cues to overeating → available foods and larger portions override satiation
food supply
physical activity → high screen time and sedentary jobs increase risk
built environment → driving instead of walking, food deserts
food desert
areas where people have limited access to affordable, healthy foods
what are 3 lifestyle components of a successful weight management program?
dietary strategies, physical activity, and behavior modification
when this isn’t enough, there are medical treatment options, such as drugs and bariatric surgery
what are dietary strategies for managing weight?
control portion sizes
eat low energy-density foods (more nutrients/volume, less kcals)
avoid empty calories
follow a food guide, ex. MyPlate or keep a food record
ensure adequate calorie intake (maintain BMR)
eat high fiber and lean proteins (more satiating)
what are behavior modification strategies for weight management?
shopping after eating, from a list/app, shop around the perimeter for fresh foods, and read food labels to make educated choices
planning meals in advance, keep healthy foods at the ready, more activity and less snacking, eat at scheduled times without skipping meals, and drink lots of water
reduce triggers by storing food out of sight, eating in dining areas, avoiding buffets, and keeping dishes off the table
Glucagon-like peptide receptor agonists (GLP-1s)
weight loss medications designed to mimic the effects of a natural hormone that helps regulate blood sugar and reduce appetite
recommended in combination with lifestyle strategies
How do GLP-1 drugs differ from older weight loss drugs?
older drugs broadly suppressed appetite and metabolism
new drugs act as a natural hormone
what are the limitations of GLP-1 drugs?
high cost
limited supply
unequal access