Depression (Top Drugs)

Brand, Generic, Dosing, MOA, BBW

What is the BBW of depression indicated medications?

Increased suicidal thoughts and actions in children, adolescents, and young adults

Amitriptyline (Brand)

Elavil

Elavil (generic)

Amitriptyline

Elavil (dosing)

10-100mg po in divided doses or at bedtime

Amitriptyline (dosing)

10-100 mg po in divided doses or at bedtime

Amitriptyline (MOA)

SNRI (at presynaptic nerve terminal which increases activity at post synaptic terminals

Bupropion (brand)

Wellbutrin, Wellbutrin SR, Wellbutrin XL, Zyban

Wellbutrin, Zyban (generic)

Bupropion

Bupropion (dosing)

150mg ER qd

Wellbutrin, Zyban (dosing)

150mg ER qd

Bupropion (MOA)

blocks neuronal uptake of norepinephrine and dopamine in the CNS

Citalopram (brand)

Celexa

Celexa (generic)

Citalopram

Citalopram (dosing)

20mg po qd

Celexa (dosing)

20mg po qd

Citalopram/Celexa (MOA)

SSRI in the CNS

Desvenlafaxine (brand)

Pristiq

Pristiq (generic)

Desvenlafaxine

Desvenlafaxine (dosing)

50mg po qd

Pristiq (dosing)

50mg po qd

Desvenlfaxine/Pristiq (MOA)

SNRI

Duloxetine (brand)

Cymbalta

Cymbalta (generic)

Duloxetine

Duloxetine (dosing)

40-60mg po qd

Cymbalta (dosing)

40-60mg po qd

Duloxetine/Cymbalta (MOA)

SNRI

Escitalopram (brand)

Lexapro

Lexapro (generic)

Escitalopram

Escitalopram (Dosing)

10mg po qd

Lexapro (dosing)

10mg po qd

Escitalopram/Lexapro (MOA)

SSRI

Fluoxetine (brand)

Prozac, Sarafem

Prozac, Saracen (generic)

Fluoxetine

FLuoxetine (dosing)

20mg po qd

Prozac, Saracen (dosing)

20mg po qd

Fluoxetine/Prozac (MOA)

SSRI

Mirtazapine (brand)

Remeron

Remeron (generic)

Mirtazapine

Mirtazapine (Dosing)

15mg po qd

Remeron (dosing)

15mg po qd

Mirtazapine/Remeron (MOA)

central pre-synaptic alpha 2 antagonist. Antagonist of 5HT2 and 5HT3 receptors. Inhibitor of histamine H1 receptor and alpha 1 and muscarinic receptors

Nortriptyline (brand)

Pamelor

Pamela (generic)

Nortriptyline

Nortriptyline (dosing)

50mg po qd in single or divided doses

Pamela (dosing)

50mg po qd in single or divided doses

Paroxetine (brand)

Paxil, Paxil XR, Pexeva

Paxil/Pexeva (generic)

Paroxetine

paroxetine (dosing)

20mg po qd

Paxil/Pexeva (dosing)

20mg po qd

Paroxetine/Paxil (pexeva) (MOA)

SSRI

Sertraline (brand)

Zoloft

Zoloft (generic)

Sertraline

Sertraline (dosing)

50mg po qd

Zoloft (dosing)

50mg po qd

Sertraline/Zoloft (MOA)

SSRI

Trazodone (brand)

Desyrel

Desyrel (generic)

Trazodone

trazodone (dosing)

150mg po qd in single or divided doses

Desyrel (dosing)

150mg po qd in single or divided doses

Trazodone/Desyrel (MOA)

inhibits serotonin reuptake by brain synaptosomes

Venlafaxine (brand)

Effexor, Effexor XR

Venlafaxine (dosing)

75mg XR po qd

Effexor (dosing)

75mg XR po qd

Venlafaxine/Effexor (MOA)

SNRI

Vilazodone HCl (brand)

Viibryd

Viibryd (generic)

Vilazodone HCl

Vilazodone (dosing)

40mg po qd with food

Vilazodone HCl/Viibryd (MOA)

selective inhibition of serotonin reuptake in the CNS and partial and partial agonist of 5-HT (1A) receptors

Viibryd (dosing)

40mg po qd with food

Vortioxetine (brand)

Trintellix

Trintellix (generic)

Vortioxetine

Vortioxetine (dosing)

20mg po qd

Trintellix (dosing)

20mg po qd

Vortioxetine/Trintellix (MOA)

inhibits the reuptake of serotonin; antagonizes 5-HT3, 5-HT1D, and 5-HT7 receptors; agonizes 5-HT1A receptors; and is a 5-HT1B receptor partial agonist