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psychosomatic medicine
The study of how psychological and social factors affect physical disorders used to be distinct and somewhat separate from the remainder of psychopathology. Early on, the field was called ____
second revolution in public health
The shift in focus from infectious disease to psychological factors has been called the ___
behavioral medicine
knowledge derived from behavioral science is applied to the prevention, diagnosis, and treatment of medical problems.
behavioral medicine
This is an interdisciplinary field in which psychologists, physicians, and other health professionals work closely together to develop new treatments and preventive strategies
health psychology
not interdisciplinary; Practitioners study psychological factors that are important to the promotion and maintenance of health; they also analyze and recommend improvements in health-care systems and health policy formation within the discipline of psychology
Smoking
the leading preventable cause of death in the United States
sustained stress
Selye theorized that the body goes through several stages in response to ___
alarm
The first phase is a type of ___ response to immediate danger or threat
resistance
With continuing stress, we seem to pass into a stage of ___, in which we mobilize various coping mechanisms to respond to the stress.
exhaustion
Finally, if the stress is too intense or lasts too long, we may enter a stage of ___, in which our bodies suffer permanent damage or death
general adaptation syndrome (GAS)
the idea that chronic stress may inflict permanent bodily damage or contribute to disease has been confirmed and elaborated on in recent years
Hans Selye
proponent for GAS
stress
physiological response of the individual to a stressor.
hypothalamic-pituitary-adrenocortical (HPA) axis
activity of the endocrine system increases when we are stressed, primarily through activation of the ____
corticotropin-releasing factor (CFR)
is secreted by the hypothalamus and stimulates the pituitary gland
cortisol
the pituitary gland (along with the autonomic nervous system) activates the adrenal gland, which secretes, among other things, the hormone
stress hormones
Because of their close relationship to the stress response, cortisol and other related hormones are known as the ___
hippocampus
when stimulated by this hormone during HPA axis activity, the ___helps to turn off the stress response, completing a feedback loop between the limbic system and the various parts of the HPA axis
self-efficacy
a sense of control and confidence that we can cope with stress or challenges
immune system
the effect of stress on susceptibility to infections is mediated through the ______, which protects the body from any foreign materials that may enter it.
antigens
The immune system identifies and eliminates foreign materials, called ___, in the body.
humoral and cellular
The immune system has two main parts:
leukocytes
White blood cells, called ___, do most of the work.
macrophages
one of the body’s first lines of defense: They surround identifiable antigens and destroy them; signal lymphocytes
B cells
operate within the humoral part of the immune system, releasing molecules that seek antigens in blood and other bodily fluids with the purpose of neutralizing them.
immunoglobulins
The B cells produce highly specific molecules called ____that act as antibodies, which combine with the antigens to neutralize them.
memory B cells
After the antigens are neutralized, a subgroup called _____ are created so that the next time that antigen is encountered the immune system response will be even faster.
T cells
lymphocytes that operate in the cellular branch of the immune system; don’t produce antibodies
killer T cells
directly destroys viral infections and cancerous processes
memory T cells
are created to speed future responses to the same antigen.
T4 cells/ helper T cells
they enhance the immune system response by signaling B cells to produce antibodies and telling other T cells to destroy the antigen.
suppressor T cells
suppress the production of antibodies by B cells when they are no longer needed.
autoimmune disease
With too many T4 cells, the immune system is overreactive and may attack the body’s normal cells rather than antigens. When this happens, we have what is called an ____
rheumatoid arthritis
AIDS
examples of autoimmnue diseases
human immunodeficiency virus (HIV)
directly attacks the helper T cells, lymphocytes that are crucial to both humoral and cellular immunity, thereby severely weakening the immune system
psychoneuroimmunology
the object of study is psychological influences on the neurological responding implicated in our immune response.
AIDS-related complex (ARC)
After several months to several years with no symptoms, patients may develop minor health problems such as weight loss, fever, and night sweats—symptoms that make up the condition known as
highly active antiretroviral therapy (HAART)
Clinical scientists have developed powerful new combinations of drugs referred to as ___ that suppress the virus in those infected with HIV, even in advanced cases
psychoncology
the discovery that the development and course of different varieties of cancer are subject to psychosocial influences .This has resulted in a new field of study called
oncology
study of cancer
cardiovascular system
consists of the heart, blood vessels, and complex control mechanisms for regulating their function
cerebral vascular accidents (CVAs) or strokes
are temporary blockages of blood vessels leading to the brain or a rupture of blood vessels in the brain that results in temporary or permanent brain damage and loss of functioning.
Raynaud’s syndrome
lose circulation to peripheral parts of their bodies such as their fingers and toes, suffering some pain and continual sensations of cold in their hands and feet.
hypertension
is a major risk factor not only for stroke and heart disease but also for kidney disease
essential hypertension
hypertension that have no specific verifiable physical cause
160 over 95 mmg
Blood pressure is defined as high by the World Health Organization if it exceed ___
systolic blood pressure
pressure when the heart is pumping blood
diastolic blood pressure
pressure between beats when the heart is at rest
diastolic pressure
Elevations in _____ seem to be more worrisome in terms of risk of disease.
hypertension
has been called the “silent killer” because there are few—if any—symptoms and most people don’t know they have it.
sympathetic branch
When the ____ of the autonomic nervous system becomes active, one consequence is the constriction of blood vessels, which produces greater resistance against circulation; that is, blood pressure is elevated
Sodium and water regulation,
one of the functions of the kidneys, is also important in regulating blood pressure.
Loneliness, depression, and feelings of uncontrollability
are psychological mechanisms that may contribute to the association between hypertension and social support
warm touch
one study with married couples found that practicing a ____ (frequent affectionate touching) as a way of communicating love and support significantly decreased blood pressure
coronary heart disease (CHD)
is a blockage of the arteries supplying blood to the heart muscle
angina pectoris / angina
Chest pain resulting from partial obstruction of the arteries
atherosclerosis
occurs when a fatty substance or plaque builds up inside the arteries and causes an obstruction
ischemia
is the name for deficiency of blood to a body part caused by the narrowing of the arteries by too much plaque.
myocardial infarction / heart attack
is the death of heart tissue when a specific artery becomes clogged with plaque
myocardial stunning
evere stress, as in learning that a family member suddenly died, can lead on rare occasions to a condition called _____, which is basically heart failure
type A behavior pattern
excessive competitive drive, a sense of always being pressured for time, impatience, incredible amounts of energy that may show up in accelerated speech and motor activity, and angry outbursts
type B behavior pattern
more relaxed, less concerned about deadlines, and seldom feels the pressure or, perhaps, the excitement of challenges or overriding ambition
Meyer Friedman and Ray Rosenman
cardiologists who identified the types of behavior patterns
acute pain
typically follows an injury and disappears once the injury heals or is effectively treated, often within a month
chronic pain
, may begin with an acute episode but does not decrease over time, even when the injury has healed or effective treatments have been administered.
pain
the subjective experience reported by the patient
pain behaviors
overt manifestations of this experience,
suffering
emotional component of pain
phantom limb pain
people who have lost an arm or leg feel excruciating pain in the limb that is no longer there.
gate control theory of pain
According to this theory, nerve impulses from painful stimuli make their way to the spinal column and from there to the brain
dorsal horns of the spinal cord
acts as a “gate” and may open and transmit sensations of pain if the stimulation is sufficiently intense
small fibers
A-delta and C fibers
large fibers
A-beta fibers
small fibers
tend to open the gate, thereby increasing the transmission of painful stimuli,
large fibers
close the gate
endogenous opioids/endorphins/enkephalins
are distributed widely throughout the body, they may be implicated in a variety of psychopathological symptoms and conditions, including tolerance and dependence, eating disorders, and stress reactions
endogenous opioids/endorphins/enkephalins
They are commonly associated with the “runner’s high” that occurs after intense (and sometimes painful) physical activity
women
which gender experiences more migraine headaches, arthritis, carpal tunnel syndrome, and temporomandibular joint (TMJ) pain in the jaw?
men
which gender have more cardiac pain and backache
estrogen-dependent neuronal system
The female neurochemistry may be based on an ___ that may have evolved to cope with the pain associated with reproductive activit
neurasthenia
In the mid-19th century, a rapidly growing number of patients suffered from lack of energy, marked fatigue, a variety of aches and pains, and occasionally low-grade fever. No physical pathology could be discovered,; was called ___ meaning lack of nerve strength
chronic fatigue syndrome (CFS)
are almost identical to those of neurasthenia and have been attributed to various causes including viral infection
Epstein-Barr virus and XMRV
viruses associated with CFS
XMRV
a retrovirus with some similarities to HIV
biofeedback
process of making patients aware of specific physiological functions that, ordinarily, they would not notice consciously, such as heart rate, blood pressure, muscle tension in specific areas of the body, electroencephalogram rhythms (brain waves), and patterns of blood flow
progressive muscle relaxation
people purposely tense different muscle groups in a sequential fashion followed by relaxing each specific muscle group.
transcendental meditation
attention is focused solely on a repeated syllable, or the mantra
relaxation response
in which a person silently repeats a mantra to minimize distraction by closing the mind to intruding thoughts.
time-management training
patients are taught to prioritize their activities and pay less attention to nonessential demands
assertiveness training
in which patients learn to stand up for themselves in an appropriate way.
Stanford Three Community Study
One of the best-known and most successful efforts to reduce risk factors for disease in the community
killer T cells
this subgroup targets viral infections within the cells by directly destroying the antigens
macrophages
A type of leukocyte that surrounds identifiable antigens and destroys them.
immunoglobulins
Highly specific molecules that act as antibodies. They combine with antigens to neutralize them
B cells
Lymphocytes that operate within the humoral part of the system and circulate in the blood and bodily fluids.
memory B cells
These are created so that when a specific antigen is encountered in the future, the immune response will be faster
suppressor T cells
These T cells stop the production of antibodies by B cells when they are no longer needed.
c. Cuts, bruises, and other injuries
Which of the following is not considered part of the experience of pain?
a. The subjective impression of pain as reported by the patient
b. Pain behaviors or overt manifestations of pain
c. Cuts, bruises, and other injuries
d. An emotional component called suffering
development
Some evidence shows that psychological factors may contribute to both the course and the ________ of cancer, AIDS, and other diseases, as well as treatment and recovery.
hypertension; coronary heart disease
Psychosocial and biological factors contribute to the development of ________, a potentially deadly condition of high blood pressure, and to the development of ________, the blockage of arteries supplying blood to the heart muscle.