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Hormone
a regulatory substance produced in an organism and transported in tissue fluids such as blood to stimulate specific cells or tissues into action
endocrine
secrete hormones into bloodstream
exocrine
secrete hormones/substances into ducts/organs/surface of the body
trophic hormone and example
hormones that are released after being stimulated by another hormone
ACTH → stimulates adrenal cortex
PRL → stimulates milk, feel good
TSH → stimulates thyroid gland to release T3/T4
GH → stimulates cell division, protein synthesis
biogenic
water-soluble (except thyroid hormone), derived from amino avid that is modiste ( e.g. tyrosine) → norepinephrine, melatonin
protein
water-soluble, consists of amino acids chains, three subgroups (small peptides, large polypeptides, glycopeptides) → antidiuretic hormone, insulin, glucagon
steroid
lipid soluble formed from cholesterol → estrogen, progesterone
thyroid stimulating hormone
released from anterior, stimulates development of thyroid gland and secretion of thyroid hormones
follicle stimulating hormone
anterior, one of two gonadotropins, stimulate testes and ovaries to produce testosterone and estrogen
luteinizing hormone
anterior, one of two gonadotropins, stimulate male and female gonades, released by GnRH
adrenocorticotropic hormone
, anterior, acts on the adrenal cortex to cause release of corticosteroids (cortisol)
growth hormone
anterior, regualtes and controls growth
prolactin
anterior, produced by lactorophs, production of breast milk
oxytocin
posterior, stretching of uterus, milk production
antidiuretic hormone
posterior, no pee
thyroid hormone
t3 and t4, set basal metabolic rate, thermogreulation, growth and development, synergism with SNS, → made from follicle cells and stimulated from TSH
calcitonin
parafollicular cells, stimulated by increased CA and secrets calcium ion
parathyroid hormone
parathyroid hormone, chief cells , increase concentration of calcium ions in the blood
mineralocorticoids: aldosterone
zona glomerulosa, maintains concentrations of extracellular sodium and potassium with in range
Glucocorticoids: Cortisol
zona fasciculata, metabolic homeostasis,
Gonadocorticoids: Androgens
zona recticularis: hormones same as sex hormones on small scale
Catecholamines: Norepi and epi
adrenal medulla, simulations from preganglionic sympathetic neurons and ACTH, increase rate and force of hear contractions
insulin
beta cells , lowers level of glucose in blood
glucagon
alpha cells, increase levels of glucose in the blood
estrogen
ovaries; stimulates production of secondary sex hormones
progesterone
varies; prepare body for pregnancy
testosterone
testes; bone growth and secondary sex characteristics
inhabiting
Acromegaly
enlarged hands, feet, sweating, fatigue, weak, limited mability
elevate levels of insulin like growth factor
addisons disease
tireless, salt cravings, weight loss
low sodium, high potassium, high ACTH, low, cortisol in the blood
cushing syndrome
backache, anxiety, muscle weakness, extra fat deposit on the back of the next and upper back, irregular mental cycle
too much cortisol
hypoglycemia
low glucose levels
abnormally low blood sugar levels following 72 hrs fasting
diabetes insipidus
very thirsty, large amounts of pale urine,
normal blood glucose level, no glucose in the urine, low ADH level in blood
hyperparathyroidism
excessive thrust, weak or broken bones, fatigue, nausea
too much parathyroid hormone
hypoparathyroidism
neural excitability with tenting (muscle spasms) and convulsions
not enough parathyroid hormone
hyperthyroidism
elevated body temp, extreme sweating, nervousness, rapid heart rate, weight loss, irregular mental cycle in females
high thyrozine and low TSH in the blood
hypothyroidism
tiredness, sensitive to cold, dry skin, weight gain, puffy hair,
low thyroxine and high TSH in the blood
Gigantism
large body stature with increased height compare to peers; muscles and organs may be enlarged as well
high GH levels and high insulin like growth factors
Grave’s disease
elevated metabolic rate, eating, irregular hear rate, weight loss, protrusion of the eyeball and nervousness
too much thyroid hormone
Pituitary Dwarfism
large forehead, smaller body parts
-hypo secretion of growth hormone, lowered GF levels in the blood
PCOS
acne, unwanted hair growth, weight gain, fatigue, infertility, mood changes, sleep problems
elevated levels of testosterone and LH, low levels of RSH in blood
Type I diabetes Mellitus
frequent unirations, excessive thirst
glucose in urine, elevated blood glucose, islet cell in the blood
Type 2 Diabetes Mellitus
request urinations, excessive thrist
glucose in urine, elevated glucose levels, no islet cell antibody in the blood