oswald avery

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Last updated 2:53 PM on 3/3/25
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11 Terms

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Transformation Principle

The concept that DNA is the material responsible for genetic transformation in bacteria.

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Oswald Avery

A Canadian-born American bacteriologist who discovered the transforming principle was DNA.

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Fredrick Griffith

A scientist whose work with bacterial strains led to the discovery of the transformation principle.

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Virulent

A strain of bacteria that is capable of causing disease.

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Nonvirulent

A strain of bacteria that does not cause disease.

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Avery-MacLeod-McCarty Experiment

An experiment that demonstrated DNA is the transforming principle.

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Heat-killed S Cells

Bacterial cells that were killed by heat but used in transformation experiments to show the transfer of DNA.

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DNAse

An enzyme that breaks down DNA, used in the transformation experiments to confirm DNA as the transforming principle.

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Hypothesis

A proposed explanation based on limited evidence as a starting point for further investigation, in this case, that DNA is the transforming principle.

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Inheritance

The transmission of genetic characteristics from one generation to another.

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Polysaccharide Capsule

A protective layer surrounding some bacteria that makes them virulent.