7 - histogenesis of tooth dentin. origin and ocmposition. formation of dentin matrix and dentin mineralisation

0.0(0)
Studied by 0 people
call kaiCall Kai
learnLearn
examPractice Test
spaced repetitionSpaced Repetition
heart puzzleMatch
flashcardsFlashcards
GameKnowt Play
Card Sorting

1/6

encourage image

There's no tags or description

Looks like no tags are added yet.

Last updated 8:37 AM on 5/21/26
Name
Mastery
Learn
Test
Matching
Spaced
Call with Kai

No analytics yet

Send a link to your students to track their progress

7 Terms

1
New cards

Origin of dentin

  • formed by odontoblasts that differentiated from ectomesenchymal cells of the dental papilla

  • Dental papilla is the formative organ of dentin and eventually becomes the pulp

2
New cards

Composition of dentin

  • Inorganic component - 87% hydroxyapatite crystals, carbonate apatite and fluroapatite 

  • Organic component - 13% collagen fibres and small amounts of other proteins (dentin phosphoprotein, dentin matrix protein 1, dentin sialoprotein and other) and water 

3
New cards

when does dentinogenesis begin

  • after the final differentiation of the odontoblasts and subodontoblasts 

4
New cards

Stage 1 (of formation of dentin matrix and mineralisation) - formation of organic matrix 

  • Type 1 collage is key structural component in matrix of dentin 

  • First sign of dentin formation is appearance of Korff’s fibres, they are large diameter collagen fibrils, they originate deep among the odontoblasts and extend towards the inner epithelium 

  • Odontoblasts differentiate in the pre-existing ground substance of dental papilla, the first dentinal collagen synthesised by them is deposited in this ground substance 

5
New cards

Stage 2 (of formation of dentin matrix and mineralisation) - mineralisation

  • Phase first appears within matrix vesicles as single crystals 

  • Crystals grow rapidly and rupture from the confines of the vesicle to spread as a cluster of crystallites that fuse with adjacent crystals and form a continuous layer of mineralised matrix 

  • Globular mineralisation - involves deposition of crystals in several discrete areas of matrix, with continuous crystal enlargement and fusion eventually a single calcified mass is formed

  • Linear mineralisation - in slower depositions of crystals, mineralisation front looks like  general and mineralisation is linear  

6
New cards

what is globular mineralisation?

  • involves deposition of crystals in several discrete areas of matrix, with continuous crystal enlargement and fusion eventually a single calcified mass is formed

7
New cards

what is linear mineralisation?

  • in slower depositions of crystals, mineralisation front looks like  general and mineralisation is linear