chapter 11 cardiac pharm

decreases in erthropoietin

- decreases in RBCs

- decreases oxygen carrying capacity (pt tired)

- leads to anemia

- symptoms: fatigue, tachycardia, depression

- labs: LOW abc, hemoglobin, hematocrit (when one is low they're all low)

decrease in immune function

-increase risk of infection

epoetin alfa action

- literally giving erythropoietin

- stimulates RBCs for its action

use of epoetin alfa

- treat anemia

- BLACK BOX WARNING: pts with cancer NOT receiving chemotherapy

- end stage renal disease/ dialysis patients

pharmacokinetics of epotein alfa

SubQ or IV

adverse effects of epoetin alfa

- hypetension

-another BLACK BOX WARNING: should not give this med if hemoglobin is 12 or above OR if they have chronic kidney disease we DONT want it above 11

contraindications of epoetin alfa

uncontrolled hypertension

nursing implications of epoetin alfa

-give at end of dialysis a

action of filgrastim

stimulate WBC + neutrophils to help fight infection better (neutropenia)

use of filgrastim

prevent infections in patients with neutropenia

adverse effects of filgrastim

flu like symptoms