short answer psych

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Last updated 4:16 AM on 4/9/26
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4 Terms

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Opioids and reward circuitry

Opioids - reinforcing by affirming dopamine and GABA neurotransmission

  • bind to mu receptors on GABA neurons in the VTA and Nucleus accumbens

2
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Place preference study

Siegel et al. 1982

Rats are given drug - in black room

Given saline - in yellow room

Given fatal dose - 37% died in usual room - twice as many died in the different room

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Siegel et al 1982

Tolerance develops to most of the effects of opioids

Occurs at different rates for different effects

  • develops more rapidly to negative effects compared to euphoric effects

4
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Med use - marijuana

Glaucoma, increased appetite, autoimmune diseases, dronabinol