M6: Microbiology, Parasitology, and Public Health - Virology - Part 3.3 - Antiviral agents

Anti HSV agents:

I. Acyclovir

II. Valacyclovir

III. Famciclovir

IV. Penciclovir

V. Docosanol

VI. Trifluridine

VII. Valomaciclovir

a. I, II, III, IV, V, VI, VII

b. I, II, III, IV, V

c. III, IV, V, VI, VII

d. I, II, III, VII

e. I, II, III, IV

a. I, II, III, IV, V, VI, VII

DOC for HSV.

a. Acyclovir

b. Valacyclovir

c. Famciclovir

d. Trifluridine

e. Valomaciclovir

a. Acyclovir

Anti-HSV prodrug.

a. Acyclovir

b. Valacyclovir

c. Famciclovir

d. Trifluridine

e. Valomaciclovir

c. Famciclovir

Eye drop anti-HSV.

a. Acyclovir

b. Valacyclovir

c. Famciclovir

d. Trifluridine

e. Valomaciclovir

d. Trifluridine

Primary treatment EBV.

a. Acyclovir

b. Valacyclovir

c. Famciclovir

d. Trifluridine

e. Valomaciclovir

e. Valomaciclovir

Anti CMV except:

a. Ganciclovir

b. Valganciclovir

c. Cidofovir

d. Foacarnet

e. None

e. None

DOC for CMV.

a. Ganciclovir

b. Valganciclovir

c. Cidofovir

d. Foacarnet

e. None

a. Ganciclovir

Blocker of host kinase.

a. Trifluridine

b. Cidofovir

c. Foscarnet

d. a and b

e. All

d. a and b

Block conversion of diphosphate to triphosphate.

a. Trifluridine

b. Cidofovir

c. Foscarnet

d. a and b

e. All

c. Foscarnet

Anti-retroviral agents except:

a. NRTI/NNRTI

b. Entry inhibitor

c. Fusion inhibitor

d. Protease inhibitor

e. Integrase inhibitor

f. None

f. None

All of the following are nucleoside reverse transcriptase inhibitors (NRTI)

Didanosine

Adefovir

Zidovudine

Zalcitabine

Lamivudine

Emtricitabine

Stavudine

Tenofovir

a. True

b. False

a. True

"DAZZLEST"

Aka Abacavir.

a. Didanosine

b. Adefovir

c. Zidovudine

d. Zalcitabine

e. Lamivudine

b. Adefovir

Non nucleoside reverse transcriptase inhibitor except:

a. Efavirenz

b. Delavirdine

c. Nevirapine

d. Etravirine

e. Enfuvirtide

f. None

e. Enfuvirtide - this is fusion inhibitor.

Which is fusion inhibitor?

a. Efavirenz

b. Delavirdine

c. Nevirapine

d. Etravirine

e. Enfuvirtide

e. Enfuvirtide

Protease inhibitor:

a. Indinavir

b. Enfuvirtide

c. Maraviroc

d. Raltegravir

e. a and b

f. b and c

a. Indinavir - "-navirs"

Entry inhibitor:

a. Indinavir

b. Enfuvirtide

c. Maraviroc

d. Raltegravir

e. a and b

f. b and c

f. b and c

Enfuvirtide

Maraviroc

Entry inhibitor specifically by blocking fusion through gp41.

a. Indinavir

b. Enfuvirtide

c. Maraviroc

d. Raltegravir

e. a and b

f. b and c

b. Enfuvirtide

Entry inhibitor specifically by blocking CCR5 receptor which is a receptor on the surface of CD4 cells that attaches to gp120.

a. Indinavir

b. Enfuvirtide

c. Maraviroc

d. Raltegravir

e. a and b

f. b and c

c. Maraviroc

Integrase inhibitor:

a. Indinavir

b. Enfuvirtide

c. Maraviroc

d. Raltegravir

e. a and b

f. b and c

d. Raltegravir - "-gravirs"

Used as anti-HBV and anti-HCV specifically by activating antiviral cytokines leading to immunomodulation.

a. Interferon-a

b. Ribavirin

c. Adefovir

d. Entecavir

a. Interferon-a

Anti-HBV inhibits viral DNA synthesis. This include the following except:

a. Lamivudine

b. Telbivudine

c. Clevudine

d. Adefovir

e. Entecavir

f. None

f. None

Anti-HCV:

a. Ribavirin

b. Telaprevir

c. Boceprevir

d. a and b

e. b and c

f. All

f. All

Anti-HCV that inhibits RNA-dependent RNA polymerase:

a. Ribavirin

b. Telaprevir

c. Boceprevir

d. a and b

e. b and c

f. All

a. Ribavirin

Anti-HCV that are protease inhibitor.

a. Ribavirin

b. Telaprevir

c. Boceprevir

d. a and b

e. b and c

f. All

e. b and c

Telaprevir

Boceprevir

Anti-influenza agents except:

a. Amantadine

b. Rimantadine

c. Oseltamivir

d. Zanamivir

e. None

e. None

Anti-influenza agents that inhibits viral uncoating and used for Influenza A:

a. Amantadine

b. Rimantadine

c. Oseltamivir

d. Zanamivir

e. a and b

f. c and d

e. a and b

Anti-influenza that has anti parkinsonism activity.

a. Amantadine

b. Rimantadine

c. Oseltamivir

d. Zanamivir

e. a and b

f. c and d

a. Amantadine

Symmetrel

a. Amantadine

b. Rimantadine

c. Oseltamivir

d. Zanamivir

a. Amantadine

Anti-influenza agents that are neuraminidase inhibitor and used for influenza A and B.

a. Amantadine

b. Rimantadine

c. Oseltamivir

d. Zanamivir

e. a and b

f. c and d

f. c and d - "-mivirs"

DOC for influenza.

a. Amantadine

b. Rimantadine

c. Oseltamivir

d. Zanamivir

c. Oseltamivir