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These flashcards cover the key concepts, applications, and concerns regarding nanoparticles in the food sector as discussed in the lecture.
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What applications of nanoparticles in the food sector ?
food preservation, packaging, nutrient delivery systems, and smart packaging.
What are the potential health concerns associated with nanoparticles?
accumulation in the body,
potential risks for cancer
inflammatory diseases
concerns over nanotoxicity.
What is the length scale of nanomaterials?
from 1 to 100 nm
What is the significance of the change in resolution when using electron microscopy? (SEM/TEM)
Electron microscopy can visualize structures at resolutions between 0.5 to 4 nm, which allows for detailed imaging of nanoparticles.
What are amyloid fibrils and their relevance in the lecture?
Amyloid fibrils are protein aggregates linked to diseases (Parkinson, Alzheimer) and can interact with metallic nanoparticles for applications such as catalysis.
What is nanotoxicity?
Nanotoxicity refers to the potential harmful effects of nanoparticles on health and the environment.
How does the particle size affect bioavailability according to the lecture?
Smaller particle sizes can greatly enhance the bioavailability of certain nutrients but may also increase the uptake of undesirable substances.
Tell the range for the AFM (atomic force microscopy) and how it work
1nm, a tip is very close to the sample and mesure every changes on the structure (peaks)
Explain how metallic nanoparticles are used with amyloid fibril
from protein (ex. beta-lactoglobulin from bovine), liked with AuCl4-, and use for reduction of potential polluants (filtration process for water purification)
name some polluants in water
mercury, radioactive compounds
what is nanoencapsulation
nano capsule for oral intake which contains vitamins or active compounds trapped (nano emulsion)
what are the + of nano encapsulation
-higher stability
-improve bioavailability
-controlled release
what could be the - of nano encapsulation
-high surface area = high reactivity
-ex : excess of vit.E could be problematic soi boosting bioavailability could be harmful
-imagine the intake of pesticides or hormones = could be bad
Explain iron fortification in rice
reverse engineering
-Increase vit A absorption in the small intestine
-minimization of inhibitors
name a risk component for nanoparticules
TiO2 (inorganic component) : application in cosmetics, food industry, ceramics, color and pigments, sunscreen
Potential toxicity (DNA damage=genotoxicity)
How metallic nanoparticles can be use as a food tracer
Gold (Au) and Silver (Ag) nanoparticles have specific antibodies or DNA aptamers to detect food contaminants and allergens with high precision. These sensors detect chemical changes signaling fraud, such as in wine or oil testing.
Name a natural nanoparticule in food
Casein micelles in milk