T6 Maiden- The Natural History of Infectious Disease I + II: Bacterial Diseases + viral and eukaryotic pathogens

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Last updated 8:26 AM on 6/4/26
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4 Terms

1
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what are koch’s postulates and how have they been modified?

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2
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how do ‘healthy’ bacteria cause disease?

  • in the human microbiota, professional pathogens and opportunistic pathogens are rare

however disease can also be caused by the healthy microbiota:

  • when the bacteria gain virulence factors (eg. diptheria toxin-encoding phage)

  • by ‘accidentalinvasions- failed/dysfunctional host interactions (eg. meningococcus)

  • following host immune suppression (eg. latent tuberculosis), especially post-transplants

  • when they change host biology (eg. autoimmune responses and cancers)

3
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why could smallpox be eradicated and what was the result of this?

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4
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why did we think polio was possible to eradicate and why wasn’t it possible?

  • due to vaccine optimism following smallpox eradication in 1980

<ul><li><p>due to vaccine optimism following smallpox eradication in 1980</p></li></ul><p></p>