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Which opioids are classified as weak
Codeine and tramadol
Which opioids are classified as strong
Morphine
Oxycodone
Fentanyl
Methadone
What is the WHO analgesic ladder used for
Stepwise management of pain, mainly in palliative care, cancer and acute px
Why is the WHO analgesic ladder not suitable for chronic non-cancer pain?
Does not account for long term risks such as dependence and tolerance
Name the three steps of the WHO analgesic ladder
1.
2.
3.
Paracetamol or NSAIDs
Add a weak opioid
Replace with a strong opioid
What is the mechanism of action of opioids
They bind to the opioid receptors in the CNS mimicking endogenous opioids.
Which endogenous neurotransmitters do opioids mimic
Endorphins, enkephalins and dynorphins
What is primary insomnia
Insomnia that is not caused by another medical, psychiatric, or substance-related condition.
What is secondary insomnia
Insomnia caused by another condition
What are common caused of secondary insomnia
Anxiety, medical conditions and medications