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What are the two types of gastritis?
Erosive
Non-erosive
What is the term for gastritis that lasts a short time and comes on abruptly?
Acute gastritis
What is the term for gastritis with insidious onset and long history?
Chronic gastritis
What is the term for gastiritis that causes erosion into the submucosa?
Ulcerative gastritis
What is the term for gastritis that causes erosion that does not penetrate to the submucosa?
Erosive gastritis
What is the term for gastritis that is inflammatory, but doesn’t produce an erosion. There is no blood.
non-erosive gastritis
What are the risk factors for gastritis?
NSAIDS
caffeine
nicotine
alcohol
cocaine
radiation therapy
H. pylori
What is the major risk factor for gastritis?
H.pylori
What % of acute gastritis can be accounted by critical illness (e.g. large burn, heart attack, stroke)?
5%
What are the symptoms of gastritis?
May have no symptoms
What is the primary vitamin deficiency caused by erosive gastritis?
B12
What symptoms can result from bleeding in erosive gastritis?
Hematemesis
Melena
What exam finding of the skin can accompany hematemesis and melena?
Pallor
What are the exam findings of gastritis?
Tenderness or pain during palpation or percussion over epigastric region
What are the special tests for gastritis?
Upper GI endoscopic exam
Barium X-ray
Blood test
Stool
What are the endoscopic findings of gastritis?
Inflammation or erosions of the stomach
What is the finding of erosive gastritis on barium x-ray?
Disrupted contour of the stomach
What are the possible blood test findings of gastritis?
Anemia
H. pylori antibodies
reduced number of WBC
What are the possible stool findings of gastritis?
H. Pylori antigen
Blood
What foods are good to eat with gastritis?
Green tea
Ginger
Yogurt
Tumeric
Slippery elm
Peppermint and garlic
What layer does an erosion have to reach to be considered an ulcer?
Submucosa or deeper
What part of the GI tract is most common for peptic ulcers?
Duodenum
Stomach
What are the risk factors for peptic ulcers?
NSAIDS
H. pylori
Zollinger Ellison syndrome
What is Zollinger Ellison syndrome?
Gastrin-producing tumor (tumor of G cell)
What age group is most affected by peptic ulcers?
Over 40 yo
What are the common symptoms of peptic ulcers?
Pain and burning (may be relieved by antacids)
Bloating
Nausea
Fullness
peritonitis
If symptoms of a peptic ulcer increases in the morning before eating, are relieved by eating, and reemerge after a period of not eating, where is the ulcer likely to be?
Duodenum*
What are the exam findings of peptic ulcer?
distress
Tenderness to palpation or percussion over epigastric region
Pallor (if hematemesis or melena is present)
decreased bowel sounds
rock hard abs
loss of weight
What special tests are used for gastric ulcers?
Upper GI endoscopic exam
Gastric secretion studies
Testing for H. pylori
X ray
Why would a gastric secretion study be performed with a gastric ulcer?
To see if it is caused by Zollinger Ellison syndrome
What is the most dangerous complication of peptide ulcers?
Perforation of the GI
What demographic is most affected by gastric tumors?
Men over 50 yo (outside the U.S.)
What are the risk factors for gastric tumors?
H. pylori
Damage to the stomach
Polyps (peutz-jegher's)
Family history of cancer
smoking
Diet (nitrates and nitrites)
What foods contain nitrates and nitrites?
Pickled and smoked foods
What type of cancer are 95% of gastric tumors?
Adenocarcinoma
What are the 4 classifications of gastric tumors?
Protruding
Penetrating
Superficial spreading
Linitis plastica
What is a protruding tumor?
Polyp-like
What is a penetrating tumor?
Ulcerating tumor
What is linitis plastica tumor
tumor with serious fibrous reaction - looks synthetic
What are the symptoms of gastric cancer?
Asymptomatic until late in course of disease
Late symptoms:
Loss of appetite, abdominal discomfort or fullness
Bloating, nausea, vomiting, bleeding (anemia), unexplained weight loss
What causes the symptoms of gastric tumors?
Dysfunction of the stomach
What are the exam findings of gastric tumors?
Rigid abdomen palpation
mass in the abdomen
painful palpation
unexplained weight loss
bloated abdomen
What are the special tests for gastric tumors?
Upper GI endoscopic exam
Barium swallow x-ray
CT scan
Biopsy
Blood test - for anemia
What are the 3 types of hiatal hernia?
Sliding
Rolling
Mixed
What is the most common type of hiatal hernia?
Sliding (95%)
What is the term for the cardia of the stomach and LES rising superior through the diaphragm?
Sliding hiatal hernia
What is the term for when the fundus of the stomach is superior to the diaphragm?
Rolling hiatal hernia
What is the term for when the fundus and LES have moved through the diaphragm?
Mixed hiatal hernia
What are the risk factors for hiatal hernia?
Smoking
Hereditary
Obesity
Pregnancy
Heavy lifting
Hard coughing/sneezing
People over 50
What are the symptoms of hiatal hernia?
Usually asymptomatic
large hiatal hernias only have symptoms due to associated GERD
What are the exam findings of Hiatal Hernia?
If symptoms exist, exam findings would be from GERD
(lesions of oral mucosa and demineralization of teeth)
What are the special tests for hiatal hernia?
Upper GI series
Upper GI endoscopy
Barium swallow
What is the endoscopic finding of Hiatal hernia?
Hourglass-shaped esophagus
(first constriction is the LES, second constriction is the diaphragm around the stomach)
What is an upper GI series?
X-ray
What are the findings of Upper GI series with a hiatal hernia?
Larger air pocket above diaphragm
What is the term for a laceration of the distal esophagus and/or proximal stomach?
Mallory weiss tear
What causes mallory weiss tears?
Severe retching
Vomiting
Prolonged hiccups
Where do mallory weiss tears occur?
Gastro-esophageal junction
What is the peak age of mallory weiss tears?
40-60 yo
Who is mallory weiss tear associated with?
Alcoholics and eating disorders
What % of all upper GI bleeds are caused by mallory weiss tears?
5%
What are the symptoms of mallory weiss tears?
Hematemsis
Coffee-gorund emesis
What is the term for black flecks in vomit due to hardened blood?
Coffee ground emesis
What are the special tests for mallory weiss tears?
Endoscopic exam
Arteriography
CBC
What is the CBC finding of mallory weiss tears?
Decreased hematocrit (RBC count)
What part of the intestines does IBS affect?
Large intestine
What % of the population is affected by IBS?
15%
What age group is most commonly affected by IBS?
Teens and 20s
T or F: IBS diagnosis requires diarrhea
False (can have constipation, or diarrhea)
What are the risk factors for IBS?
Severe enteric infection
Stressful life event
family history
What is IBSC?
IBS with constipation
What is IBSD?
IBS with loose stools, diarrhea
What is IBSM?
Mixed IBS with both constipation and diarrhea
What IBS is deranged
IBSD
What IBS is paralytic
IBS C
What is the Rome criteria used for?
Diagnosis of IBS
What is the Rome criteria?
3 month history where you have:
1. Complain of abdominal/discomfort (which could be relieved by defecation)
2. Presence of disturbed defecation (changes in pressure and consistency)
3. defecation involved in at least 2:
altered stool freq
altered stool form
straining and pushing, but nothing comes out
passage of mucus
What are the symptoms of IBS?
Abdominal pain
Bloating
Cramping
Diarrhea
Constipation
Whitish mucous in stool
What are the exam findings of IBS?
Swollen or bloated abdomen
Palpable sigmoid
Tender abdomen on plaption
Abnormal bowel sounds (borborygmi)
What are the special tests for IBS?
Blood test to rule out infection or inflammation
Stool test to rule out infection or blood
Colonoscopy to rule out pathology
Barium x-ray
CT to rule out other pathological process
T or F: There are no specific special tests for IBS, it is diagnosed if all special tests come back negative
True
What is the special diet for IBS?
FODMAP
What is the purpose of the FODMAP diet?
By eating less sugars, there is less product for intestinal bacteria to ferment and produce gas
What part of the large intestine does the appendix come off of?
Cecum
What are the potential causes of appendicitis?
Lymphoid hyperplasia (most common)
Fecolith - hard piece of stool
Foreign object
Worm infection
What is the most common cause of appendicitis?
Lymphoid hypertrophy/metaplasia
What age group is most commonly affected by appendicitis?
Teens - 20s
What % of the population develops appendicitis?
over 7-9%
What are the symptoms of appendicitis?
Epigastric or periumbilical pain
Nausea and vomiting
After a few hours, pain shifts to lower right quadrant
What are the signs for appendicitis?
Blumberg sign
Rovsing's sign
Psoas sign
Obturator sign
Kosher's sign
Low grade fever
What is the term for appendicitis pain moving to the lower right quadrant?
Kosher's sign
What is a positive blumberg sign?
Increase in discomfort as the doctor presses in sharp pain as pressure is released (+ rebound tenderness at mcburney’s point)
What is a positive rovsing's sign?
Pain in the right lower quadrant when pressing into the left lower quadrant
What is a positive psoas sign?
Extension of the right hip increases pain in RLQ
What is a positive obturator sign?
Passive internal rotation of the flexed right thigh causes pain in the RLQ
What special test is typically used to diagnose appendicitis?
History
What special test is used to diagnose appendicitis with atypical presentation?
Contrast-enhanced CT
US
Blood test
What is a finding of appendicitis on blood tests?
Leukocytosis
What is the AKA of bilaiary cholangitis?
primary sclerosing cholangitis
What other condition is associated with Biliary cholangitis?
Inflammatory bowel disease