NATURAL PRODUCTS/SUPPLEMENTS

what act regulates the safety?

dietary supplement health and education act of 1994

what does the act state?

cannot make a claim that its product is used to “diagnose, treat, cure, or prevent any disease”

adverse events are reported to what part oft he FDA?

safety reporting portal

st. john’s wort is an ___ of CYP family

inducer

avoid st. john’s wort with what?

oral contraceptives, transplant drugs, warfarin

avoid st. john’s wort with what type of serotonin drugs?

MAO-I, linezolid, SSRIs, SNRIs

the 5 g’s

garlic, ginger, ginkgo, ginseng, glucosamine

what risk do the 5 g’s give?

bleeding

what others cause bleeding risk?

vitamin e and fish oils (high dose)

coq10 is inndicated for what?

reduced risk for heart failure, and high BP

avoid coq10 in what?

pregnancy and lactation

there is a risk of what when taking coq10?

bleeding risk for patients taking warfarin

fish oils are a source of what

omega-3 fatty acids

what are fish oils indicated for?

lower triglycerides

side effects of fish oil?

fishy halitosis (bad breath), GI distress

take what type of fish oil capsul with meals or at bedtime?

enteric coated; this avoid “fishy burp” effect

what is a safet risk of fish oils?

bleeding risk if you go higher dose (>4 g/day)

garlic is typically indicated for what?

hyperlipidemia

garlic should be stopped how long before a surgery to avoid bleeding risk?

10-14 days

what natural products are for the cardiovascular system that we went over?

coq10, garlic, fish oil

st. john’s wort is typically used to treat what?

depression, anxiety

you need to be given professional advice for self-treating with st. john’s wort (t/f)

true

you need to avoid st. john’s wort in who?

px with BPD and schizophrenia

potential DDI of st john’s wort

CYP indcucer, p-glycoprotein

what loses efficacy if taken with st. john;s wort

oral contraceptives, translant drugs, warfarin, anti-HIV meds

what causes an increase risk of serotonin syndrome?

st. john’s wort; avoid taking with serotonin medications

st. johns lowers the seizure threshold (t.f)

true

melatonin is indicated for what?

innsomnia

who should avoid melatonin?

pregnant and nursing

valerian is indicated for what?

insomnia, anxiety, depression (basically a combo of st. john’s and melatonin(

side effects of valerian

HA, excitability, paradoxical insomnia

avoid valerian with what due to withdrawal effects?

benzodiazpeines

taking valerian with cns depressants can potentiate effects (t.f)

true

why should you avoid valerian in pregnacncy?

can cause uterine contraction

valerian long term use has been linked to what

hepatotoxicity

what are some medications that are CNS products we went over

st. john’s wort, melatonin, valerian, butterbur (did’t go over)

saw palmetto is indicated for what

men with prostate problems

avoid saw palmetto in what people

px on antithrombotic (anticlotting), androgenic drugs, and pregnant/nursig

what are nautral products for kidnney, urinary tract, and protstate?

saw palmetto, cranberry (didn’t do)

ginger indicated for what

N/V associated with pregnancy, as well as motion sickness

what are some digestive system products we talked about

ginger

ginger should be used in caution with what?

blood thinning drugs

ginger can be used to treat n/v in pregnancy accordig to what

american college of obstetricians and gynecologist

echinacea is indicated for what

prevent and treats cold (other resiratory infection)

when do you take echinacea

at first sign of illness

avoid echinacea in what type of patients

histrory of asthma, those with allergies to ragweed and chrysanthemum

avoid echinacea in what connditios

HIV, AIDS, MS, TB, autoimmune disorders, and those o immunosupresants

glucosamine and chondroitin is indicated for what

osteoarthritis and joint health

glucosamine is derived from what and should therefore be avoided for those with severe allergies

shellfish; you ca use chondroitine as monotherapy

avoid glucoasmine and chondroitin in who

pregnant/nnursing