Substance Use Disorder 2

ataxia is a sign of cocaine

OD

what is the MOA of methamphetamines

increases NE and DA and reduces reuptake of both

seizures and HTN crises are signs of MDMA

OD

what is the chemical name for PCP

phenylcyclohexylpiperidine

being impervious to pain is a physical sign of

PCP intoxication

paranoia and bizzare behavior are severe effects of PCP

intoxication

PCP blocks glutamate receptors which means that

it blocks pain receptors

what are some potential treatments for ketamine

medical support for HTN and respiratory distress

synethesia and distorted space/time is a sign of

hallucinogen intoxication

what are the short acting CNS stimulants

cocaine and crack

what are long acting CNS stimulants

amphetamines and methamphetamines

what is the MOA of cocaine

increases DA and NE

how is powder cocaine taken

snorted and IV

how is cocaine base (rock) taken

smoked/freebasing

euphoria is a symptom of cocaine

intoxication

dilated pupils are a sign of cocaine

intoxication

elevated BP and HR are a sign of cocaine

intoxication

N/V and insomnia are signs of cocaine

intoxication

grandiosity is a sign of cocaine

intoxication

impaired judgement is a sign of cocaine

intoxication

respiratory distress is a sign of cocaine

OD

hyperpyrexia is a sign of cocaine

OD

convulsions are a sign of cocaine

OD

hemorrhagic stroke is a sign of cocaine

OD

ventricular dysrhythmias are a sign of cocaine

OD

MI is a sign of cocaine

OD

coma and death are signs of cocaine

OD

fatigue, lethargy, and sleepiness are signs of cocaine

withdrawal

anxiety, agitation, and insomnia are signs of cocaine

withdrawal

disorientation is a sign of cocaine

withdrawal

apathy and cravings are signs of cocaine

withdrawal

depression and suicidal ideation are signs of cocaine

withdrawal

what are long term use AE of cocaine

atrophy of nasal mucosa, permanent loss of smell, injury to lungs (smoking)

what are AE of cocaine use during pregnancy

- can result in: placental abruption, early delivery, smaller head, decreased birth length and low birth weight

- long term: attention, memory, and language development deficits

methamphetamines _______ in liquid

dissolve easily

methamphetamines taste very _______ so they are not easily used for date rape drugs

bitter

dilated pupils are a sign of short term methamphetamine

intoxication

increased energy is a sign of short term methamphetamine

intoxication

increased respirations are a sign of short term methamphetamine

intoxication

hyperthermia and euphora are a sign of short term methamphetamine

intoxication

paranoia and delusions are a signs of long term methamphetamine

intoxication

hallucinations and anxiety are signs of long term methamphetamine

intoxication

potential for violence is a sign of long term methamphetamine

intoxication

respiratory distress is a sign of meth

OD

ataxia is a sign of meth

OD

hyperpyrexia and convulsions are signs of meth

OD

hemorrhagic stroke is a sign of meth

OD

ventricular dysrhythmias is a sign of meth

OD

MI is a sign of meth

OD

coma and death is a sign of meth

OD

fatigue, lethargy, and sleepiness is a sign of meth

withdrawal

anxiety, agitation, and hypersomnia is a sign of meth

withdrawal

disorientation is a sign of meth

withdrawal

apathy and cravings are signs of meth

withdrawal

depression and suicidal ideation is a sign of meth

withdrawal

what are some long term AE of meth

- parkinsonian symptoms

- cracked teeth

- skin infections

- HTN

- stroke

- angina

- dysrythmias

- respiratory damange

- renal and hepatic damage

what are some AE of meth during pregnancy

- preterm birth

- HTN

- placental abruption

- IUGR

- neonatal death

what are the priority actions for CNS OD treatment

- maintain ABCs

- provide O2

- benzos (sedation and seizure prevention)

- cooling measures

- IV antihypertensives

what is the CNS stimulant withdrawal treatment

- modafinil for excessive lethargy

- diphenhydramine and trazodone for sleepiness and agitation

- analgesics for minor pain

- benzos for sedatives short term

what is the chemical name for MDMA or ecstasy

methylenedioxymethamphetamine

eurphoria is a sign of MDMA

intoxication

disinhibition is a sign of MDMA

intoxication

increased sensuality, empathy, closeness is a sign of MDMA

intoxication

hyperthermia is a sign of MDMA

OD

cardiac dysrhythmias are signs of MDMA

OD

serotonin syndrome is a sign of MDMA

OD

confusion, delirium, and paranoia are neuro effects of MDMA

OD

what is the most common COD with MDMA

dehydration

profound depression is a sign of MDMA

withdrawal

confusion, cravings, anxiety and sleep problems are signs of MDMA

withdrawal

gamma-hydroxybutyrate (GHB) and flunitrazepam (rohypnol) are

date rape drugs

drowsiness and sedation are signs of GHB

intoxication

muscle relaxation is a sign of GHB

intoxication

slurred speech is a sign of GHB

intoxication

poor coordination is a sign of GHB

intoxication

amnesia (blackouts) is a sign of GHB

intoxication

disinhibition/risky behavior is a sign of GHB

intoxication

respiratory depression is a sign of GHB

intoxication

cheyne-stokes respirations are signs of GHB

OD

seizures are signs of GHB

OD

bradypnea and bradycardia are signs of GHB

OD

hypothermia is a sign of GHB

OD

coma and death are signs of GHB

OD

insomnia is a sign of GHB

withdrawal

tremors and sweating are signs of GHB

withdrawal

N/V are signs of GHB

withdrawal

elevates HR and BP are signs of GHB

withdrawal

psychosis or hallucinations are signs of GHB

withdrawal

risk of seizures with GHB are signs of

withdrawal

is there an antidote for ecstasy or GHB

no

what is the antidote for rohypnol

flumazenil

what are the two kinds of dissociative drugs

PCP and ketamine

having elevated VS is a physical sign of

PCP intoxication

having ataxia is a physical sign of PCP

intoxication

being assaultive is a physical sign of

PCP intoxication

being impulsive and having impaired judgement is a physical sign of PCP

intoxication

hallucinations are severe effects of

PCP intoxication

regressive or violent behavior are severe effects of PCP

intoxication

labile emotions are severe effects of PCP

intoxication

psychosis is a sign of PCP

OD