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malaria epidemiology
all ages, males, pregnant women, persons who have sickle cell anemia, war,.migration and tourism may expose people
agriculture such as harvesting may >ncrease nighttime exposure
sleeping outdoors
presence of malaria depends mainly on climate factors , tropical and subtropical areas, africa south of sahara
malaria reservoir, MOT, IP
himan reservoirs harbor the sexual forms
vector transmission, blood transfusion and congenital malaria
IP 7-30 DAYS
prevention and control of malaria
health education especially for travellers
environmental sanitation
specific measures:
mefloquine: for chloroquine-resistant strains, weekly dosage, begin 1-2 weeks before travel and 4 weeks after leaving
or Doxycycline
chloeoquine during pregnancy
malaria vaccine
Control: Notify, isolate, disinfect, treat
listinf of all sharing blood
international measures: disinsectization of aircraft before departure and upon arrival
LF epidemiology , reservoir, MOT, IP and prevention
disease of the poor, usually acquired during childhood, endemic in eight governorates
humans
bite of culex pipiens
IP 8-16 months
prevention: health education, vector control and preventive chemotherapy via Mass drug administration
visceral leishmaniasis reservoir, MOT, IP, POC
humans, wild foxes and domestic dogs
MOT: Phlebotomine sandflies, person to person teansmission reported in leishmania/HIV co-infected
IP: 2-6 MONTHS range of 10 days to years
POC: rarely transmitted p2p but infectious to sandflies as long as parasites persist in circulating blood or skin
cutaneous leishmaniasis epidemiology, reservoir, MOT, IP, POC
egypt children,
Locally variable humans wild rodents and domestic dogs
bites of infected female phlebotomine sandflies
at least a week up to many months
not directly transmitted from p2p
prevention and control of leishmaniasis
Prevention: No vaccine; early treatment, vector/dog/rodent control, avoid sandflies, use repellents & protective clothes.
Control: Notification not mandatory in Egypt; isolation precautions in visceral cases; investigate contacts/source/transmission.
Treatment: Pentavalent antimonials (sodium stibogluconate/meglumine antimonate); resistant cases → amphotericin B or pentamidine (toxic).
plague epidemiology and reservoir
common in africa, asia and south america, more common in lower social class
enzootic:low mortality of rodents keeps fleas on them
epizootic: high rodent mortality, fleas attack humans
plage MOT and IP
vector: fleas
droplet: pneumonic case during cough
IP: 1-7 days, a few days longer in immunised, shorter in primary plague pneumonia 1-4 days
plague prevention and control
Prevention (general): Rodent and flea control; fumigation (e.g., hydrogen cyanide); de‑ratting certificates for ships every 6 months; rat‑proof buildings; surveillance of rodent population; combined flea + rodent control during outbreaks; safe food storage; proper refuse disposal; reporting dead rodents.
Prevention (specific): Vaccines → live attenuated (single SC) and killed (2 SC); efficacy doubtful; for travelers, residents of endemic areas, and lab/field workers; not useful for immediate outbreak protection.
Control (cases): Notify health authorities → WHO; isolation; treatment with streptomycin (DOC) or gentamicin; disinfection of sputum, pus, and contaminated items; terminal cleaning; strict precautions for handling dead bodies.
Control (contacts): Chemoprophylaxis with tetracycline or chloramphenicol for 7–10 days; isolation; quarantine of household/close (face‑to‑face) contacts.
Control (environment): Eliminate source → rodent and flea control; sanitation; monitoring during epizootics; concurrent flea + rodent control programs.
yellow fever epidemiology qnd reservoirs
africa, everyone is affected but males more, transient immunity from mother persists for 6 months
depends on season of vector
man in cities, monkeys in forest
yellow fever MOT, IP AND POC
Bite of infected mosquito
6 days IP
not communicable by contact or common vehicles
yellow fever prevention
Prevention: Live attenuated YF 17D vaccine (single SC); lifelong immunity; valid after 10 days; for jungle workers, residents, travelers.
Control (general): Vector control; aircraft disinfection; monkey quarantine; airport spraying.
Travel rules: No certificate → isolate 6 days; vaccinated on arrival → isolate until valid (≤6 days).
yellow fever control
Control (cases): Isolation 3–5 days (blood/body fluids); prevent mosquito access (nets, screening, insecticide); notify health authorities/WHO; no disinfection; symptomatic treatment.
Control (contacts): Vaccinate non‑immune contacts.
Control (environment): Source search; trace travel 3–6 days pre‑onset.
Epidemic measures: Define infected area; restrict movement (forests); assess vectors & breeding sites; community survey; repellents; identify animal reservoirs.
zika virus epidemiology, MOT, IP and prevention and control
africa and asia
through mosquitos, p2p is possible sexually
reservoir is proimates
IP not known but mostly few days to one week
prevention and control:
no vaccine, vector control and safe sex with condoms
rest, fluids, NO ASPIRIN OR NSAIDS, prevent mosquito bites
rift valley fever MOT, reservoir, IP, POC
bite of infected mosquito, contact with infected animals
sheep and cattle
3-12 days
no direct p2p
rift valley fever prevention and control
control mosquitos precautions in handling of infected animals
specific: anime vaccination, inactivated vaccine for men
control: notify, no treatment
control contacts: search for undiagnosed cases
control environment:mosquitos animal control
west nile virus MOT, reservoir, IP, POC
bites of infected mosquitos from infected birds
transplanted organs and blood transfusion (not from birds)
birds reservoir
3-12 days
no p2p transmission
west nile virus prevention and control
no vaccine available
survey for WNV in mosquitos, birds and animals
appropraite mosquito control
reduce contact with mosquitos